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Upgrades from a previous device compared to de novo cardiac resynchronization therapy in the European Society of Cardiology CRT Survey II
CM. Linde, C. Normand, N. Bogale, A. Auricchio, M. Sterlinski, G. Marinskis, C. Sticherling, A. Bulava, ÓC. Pérez, AH. Maass, KK. Witte, R. Rekvava, S. Abdelali, K. Dickstein,
Language English Country England, Great Britain
Document type Comparative Study, Journal Article, Multicenter Study
NLK
Medline Complete (EBSCOhost)
from 2000-03-01 to 1 year ago
Wiley Free Content
from 1999 to 1 year ago
PubMed
29806208
DOI
10.1002/ejhf.1235
Knihovny.cz E-resources
- MeSH
- Cardiology * MeSH
- Middle Aged MeSH
- Humans MeSH
- Survival Rate trends MeSH
- Prevalence MeSH
- Cardiac Resynchronization Therapy Devices statistics & numerical data MeSH
- Surveys and Questionnaires * MeSH
- Retrospective Studies MeSH
- Risk Factors MeSH
- Aged MeSH
- Societies, Medical * MeSH
- Heart Failure epidemiology therapy MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Comparative Study MeSH
- Geographicals
- Europe MeSH
BACKGROUND: To date, there are no data from randomized controlled studies on the benefit of cardiac resynchronization therapy (CRT) when implanted as an upgrade in patients with a previous device as compared to de novo CRT. In the CRT Survey II we compared the baseline data of patients upgraded to CRT (CRT-P/CRT-D) from a previous pacemaker (PM) or implantable cardioverter-defibrillator (ICD) to de novo CRT implantation. METHODS AND RESULTS: In the European CRT Survey II, clinical practice data of patients undergoing CRT and/or ICD implantation across 42 European Society of Cardiology (ESC) countries were collected between October 2015 and December 2016. Out of a total of 11 088 patients, 2396 (23.2%) were upgraded from a previous PM or ICD and 7933 (76.8%) underwent de novo implantation. Compared to de novo implantations, upgraded patients were older, more often male, more frequently had ischaemic heart failure aetiology, atrial fibrillation, reduced renal function, worse heart failure symptoms, and higher N-terminal pro-B-type natriuretic peptide levels. Upgraded patients were more often PM-dependent and less frequently received CRT-D. Total peri-procedural, in-hospital complications and length of hospital stay were similar. Upgraded patients were less frequently treated with heart failure medication at discharge. CONCLUSION: Despite a lack of evidenced-based data, close to one quarter of all CRT implantations across 42 ESC countries were upgrades from a previous PM or ICD. Despite older age and worse symptoms, the CRT implantation procedures in upgraded patients were equally frequently successful and complications similar to de novo implantations. These results call for more studies.
Clinic of Heart Diseases Vilnius University Lithuania
Clinical Electrophysiology Unit Fondazione Cardiocentro Ticino Lugano Switzerland
Clinique Belvedere Rabat Morocco
Department of Cardiology Stavanger Norway
Faculty of Health and Social Sciences University of South Bohemia Ceske Budejovice Czech Republic
Heart and Vascular Theme Karolinska University Hospital and Karolinska Institutet Stockholm Sweden
Heart Rhythm Department Institute of Cardiology Warsaw Poland
Research Institute of Cardiology and Internal Diseases Almaty Kazakhstan
Unidad de Arritmias Hospital Universitari 1 Politècnic La Fe Valencia Spain
References provided by Crossref.org
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- $a BACKGROUND: To date, there are no data from randomized controlled studies on the benefit of cardiac resynchronization therapy (CRT) when implanted as an upgrade in patients with a previous device as compared to de novo CRT. In the CRT Survey II we compared the baseline data of patients upgraded to CRT (CRT-P/CRT-D) from a previous pacemaker (PM) or implantable cardioverter-defibrillator (ICD) to de novo CRT implantation. METHODS AND RESULTS: In the European CRT Survey II, clinical practice data of patients undergoing CRT and/or ICD implantation across 42 European Society of Cardiology (ESC) countries were collected between October 2015 and December 2016. Out of a total of 11 088 patients, 2396 (23.2%) were upgraded from a previous PM or ICD and 7933 (76.8%) underwent de novo implantation. Compared to de novo implantations, upgraded patients were older, more often male, more frequently had ischaemic heart failure aetiology, atrial fibrillation, reduced renal function, worse heart failure symptoms, and higher N-terminal pro-B-type natriuretic peptide levels. Upgraded patients were more often PM-dependent and less frequently received CRT-D. Total peri-procedural, in-hospital complications and length of hospital stay were similar. Upgraded patients were less frequently treated with heart failure medication at discharge. CONCLUSION: Despite a lack of evidenced-based data, close to one quarter of all CRT implantations across 42 ESC countries were upgrades from a previous PM or ICD. Despite older age and worse symptoms, the CRT implantation procedures in upgraded patients were equally frequently successful and complications similar to de novo implantations. These results call for more studies.
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