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Dermoscopy features of atypical fibroxanthoma: A multicenter study of the International Dermoscopy Society
E. Moscarella, S. Piana, F. Specchio, A. Kyrgidis, G. Nazzaro, ML. Eliceche, F. Savoia, L. Bugatti, G. Filosa, I. Zalaudek, F. Scarfi, M. Inskip, C. Rosendahl, JH. Pyne, G. Siggs, AK. Toğral, H. Cabo, L. Drlik, A. Lallas, C. Longo, G. Argenziano,
Jazyk angličtina Země Austrálie
Typ dokumentu srovnávací studie, časopisecké články, multicentrická studie
PubMed
29569417
DOI
10.1111/ajd.12802
Knihovny.cz E-zdroje
- MeSH
- bazocelulární karcinom diagnostické zobrazování MeSH
- dermatoskopie * MeSH
- fibrom diagnostické zobrazování patologie MeSH
- lidé MeSH
- nádory hlavy a krku diagnostické zobrazování patologie MeSH
- nádory kůže diagnostické zobrazování MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- spinocelulární karcinom diagnostické zobrazování MeSH
- společnosti lékařské MeSH
- studie případů a kontrol MeSH
- xantomatóza diagnostické zobrazování patologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- srovnávací studie MeSH
BACKGROUND/OBJECTIVES: Little is known about the dermoscopic features of atypical fibroxanthoma. METHODS: This was a case-control study. Atypical fibroxanthoma lesions were compared with a control group with non-melanoma skin cancer. RESULTS: Altogether 40 atypical fibroxanthoma were collected. Most developed in men (93%), appearing mainly as nodular (63%), amelanotic (93%) and ulcerated (78%) lesions. Most lesions were located on the scalp (55%) and the ears (13%). Dermoscopically, most atypical fibroxanthoma displayed red (83%) and white (70%) structureless areas and irregular linear vessels (43%). A series of features achieved statistical significance when comparing atypical fibroxanthoma with non-melanoma skin cancer. The presence of red and white structureless areas and white lines, and the absence of yellowish-white opaque scales, hairpin vessels and arborising vessels were predictive of atypical fibroxanthoma in univariate analysis. However, when squamous cell carcinoma was excluded from the analysis, none of the criteria achieved statistical significance. When basal cell carcinoma was excluded, three variables achieved statistical significance in predicting atypical fibroxanthoma: red, structureless areas, the absence of opaque yellowish-white scales and absence of white circles. CONCLUSIONS: Atypical fibroxanthomas seem to be barely distinguishable from basal cell carcinoma dermoscopically, but they are more easily distinguishable from a well to moderately differentiated squamous cell carcinoma. A histopathological examination is needed for the final diagnosis.
1st Department of Dermatology Aristotle University Thessaloniki Greece
Department of Dermatology Šumperk Hospital Šumperk Czech Republic
Dermatology and Skin Cancer Unit Arcispedale Santa Maria Nuova IRCCS Reggio Emilia Italy
Dermatology Clinic University of Trieste Hospital Maggiore Trieste Italy
Dermatology Unit 'Carlo Urbani' Hospital Jesi Italy
Dermatology Unit Italian Hospital of Buenos Aires Buenos Aires Argentina
Dermatology Unit School of Medicine University of Buenos Aires Buenos Aires Argentina
Dermatology Unit University of Campania Luigi Vanvitelli Naples Italy
Dermatology Unit University of Florence Florence Italy
Faculty of Medicine Department of Dermatology Başkent University Ankara Turkey
Pathology Unit Arcispedale Santa Maria Nuova IRCCS Reggio Emilia Italy
School of Medicine University of Queensland Brisbane Queensland Australia
Skin Patrol Skin Cancer Clinic Melbourne Victoria Australia
SunDoctors Skin Cancer Clinic Adelaide South Australia Australia
Citace poskytuje Crossref.org
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- $a BACKGROUND/OBJECTIVES: Little is known about the dermoscopic features of atypical fibroxanthoma. METHODS: This was a case-control study. Atypical fibroxanthoma lesions were compared with a control group with non-melanoma skin cancer. RESULTS: Altogether 40 atypical fibroxanthoma were collected. Most developed in men (93%), appearing mainly as nodular (63%), amelanotic (93%) and ulcerated (78%) lesions. Most lesions were located on the scalp (55%) and the ears (13%). Dermoscopically, most atypical fibroxanthoma displayed red (83%) and white (70%) structureless areas and irregular linear vessels (43%). A series of features achieved statistical significance when comparing atypical fibroxanthoma with non-melanoma skin cancer. The presence of red and white structureless areas and white lines, and the absence of yellowish-white opaque scales, hairpin vessels and arborising vessels were predictive of atypical fibroxanthoma in univariate analysis. However, when squamous cell carcinoma was excluded from the analysis, none of the criteria achieved statistical significance. When basal cell carcinoma was excluded, three variables achieved statistical significance in predicting atypical fibroxanthoma: red, structureless areas, the absence of opaque yellowish-white scales and absence of white circles. CONCLUSIONS: Atypical fibroxanthomas seem to be barely distinguishable from basal cell carcinoma dermoscopically, but they are more easily distinguishable from a well to moderately differentiated squamous cell carcinoma. A histopathological examination is needed for the final diagnosis.
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