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High hydrostatic pressure in cancer immunotherapy and biomedicine
I. Adkins, N. Hradilova, O. Palata, L. Sadilkova, L. Palova-Jelinkova, R. Spisek,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
- MeSH
- biotechnologie přístrojové vybavení metody MeSH
- dendritické buňky imunologie MeSH
- eukaryotické buňky MeSH
- hydrostatický tlak * MeSH
- imunoterapie metody MeSH
- inaktivace viru MeSH
- lidé MeSH
- nádory patologie terapie MeSH
- ortopedické výkony metody MeSH
- vakcíny imunologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
High hydrostatic pressure (HHP) has been known to affect biological systems for >100 years. In this review, we describe the technology of HHP and its effect macromolecules and physiology of eukaryotic cells. We discuss the use of HHP in cancer immunotherapy to kill tumor cells for generation of whole cell and dendritic cell-based vaccines. We further summarize the current use and perspectives of HHP application in biomedicine, specifically in orthopedic surgery and for the viral, microbial and protozoan inactivation to develop vaccines against infectious diseases.
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- $a 10.1016/j.biotechadv.2018.01.015 $2 doi
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- $a Adkins, Irena $u Sotio a.s, Prague, Czech Republic; Department of Immunology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic. Electronic address: adkins@sotio.com.
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- $a High hydrostatic pressure (HHP) has been known to affect biological systems for >100 years. In this review, we describe the technology of HHP and its effect macromolecules and physiology of eukaryotic cells. We discuss the use of HHP in cancer immunotherapy to kill tumor cells for generation of whole cell and dendritic cell-based vaccines. We further summarize the current use and perspectives of HHP application in biomedicine, specifically in orthopedic surgery and for the viral, microbial and protozoan inactivation to develop vaccines against infectious diseases.
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- $a Hradilova, Nada $u Sotio a.s, Prague, Czech Republic; Department of Immunology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
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- $a Palata, Ondrej $u Sotio a.s, Prague, Czech Republic; Department of Immunology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
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- $a Sadilkova, Lenka $u Sotio a.s, Prague, Czech Republic.
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- $a Palova-Jelinkova, Lenka $u Department of Immunology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
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- $a Spisek, Radek $u Sotio a.s, Prague, Czech Republic; Department of Immunology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
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