Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Repetitive transcranial magnetic stimulation (rTMS) modulates hippocampal structural synaptic plasticity in rats

Yue Li, Lulu Li, Weidong Pan

. 2019 ; 68 (1) : 99-105. [pub] 20181023

Jazyk angličtina Země Česko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc19024853

Repetitive transcranial magnetic stimulation (rTMS) was shown to have therapeutic potential for some neurological and psychiatric disorders. Previous studies reported that low-frequency rTMS (

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19024853
003      
CZ-PrNML
005      
20190805125505.0
007      
ta
008      
190704s2019 xr da f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.933772 $2 doi
035    __
$a (PubMed)30433805
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Li, Yue $u Beijing Key Laboratory of Bioelectromagnetics, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China
245    10
$a Repetitive transcranial magnetic stimulation (rTMS) modulates hippocampal structural synaptic plasticity in rats / $c Yue Li, Lulu Li, Weidong Pan
520    9_
$a Repetitive transcranial magnetic stimulation (rTMS) was shown to have therapeutic potential for some neurological and psychiatric disorders. Previous studies reported that low-frequency rTMS (</=1 Hz) affected synaptic plasticity in rats, however, there were few investigations to examine the possible effects of rTMS on structural synaptic plasticity changes in rats, which included the effects on synaptic morphology in the hippocampus, synaptic protein markers and Ca(2+)/calmodulin-dependent protein II (CaMKII). Sprague-Dawley rats were subject to 500 pulses of 0.5 Hz rTMS for 15 days, or sham stimulation. After last stimulation, transmission electron microscope (TEM) and real-time PCR were used to determine the effects of rTMS on synaptic plasticity. Results showed that rTMS could cause the change of structural synaptic plasticity, increase the expression of synaptic protein markers: synaptophysin (SYN) and increase the expression of CaMKII, relative to normal rats. suggesting a modulatory effect of chronic rTMS on synaptic plasticity that may be attributed to the increased expression of CaMKII in rats.
650    _2
$a zvířata $7 D000818
650    _2
$a proteinkinasa závislá na vápníku a kalmodulinu typ 2 $x metabolismus $7 D054732
650    _2
$a hipokampus $x metabolismus $x ultrastruktura $7 D006624
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a neuroplasticita $x fyziologie $7 D009473
650    _2
$a náhodné rozdělení $7 D011897
650    _2
$a krysa rodu Rattus $7 D051381
650    _2
$a potkani Sprague-Dawley $7 D017207
650    _2
$a transkraniální magnetická stimulace $x metody $7 D050781
655    _2
$a časopisecké články $7 D016428
700    1_
$a Li, Lulu $u Beijing Key Laboratory of Bioelectromagnetics, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China
700    1_
$a Pan, Weidong $u Beijing Key Laboratory of Bioelectromagnetics, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 68, č. 1 (2019), s. 99-105
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30433805 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y 4 $z 0
990    __
$a 20190704 $b ABA008
991    __
$a 20190730135437 $b ABA008
999    __
$a ok $b bmc $g 1429476 $s 1063271
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2019 $b 68 $c 1 $d 99-105 $e 20181023 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
LZP    __
$b NLK111 $a Pubmed-20190704

Najít záznam

Citační ukazatele

Možnosti archivace