Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Evidence for verbal memory enhancement with electrical brain stimulation in the lateral temporal cortex

MT. Kucewicz, BM. Berry, LR. Miller, F. Khadjevand, Y. Ezzyat, JM. Stein, V. Kremen, BH. Brinkmann, P. Wanda, MR. Sperling, R. Gorniak, KA. Davis, BC. Jobst, RE. Gross, B. Lega, J. Van Gompel, SM. Stead, DS. Rizzuto, MJ. Kahana, GA. Worrell,

. 2018 ; 141 (4) : 971-978. [pub] 20180401

Language English Country England, Great Britain

Document type Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Video-Audio Media

Persistent link   https://www.medvik.cz/link/bmc19028626

Direct electrical stimulation of the human brain can elicit sensory and motor perceptions as well as recall of memories. Stimulating higher order association areas of the lateral temporal cortex in particular was reported to activate visual and auditory memory representations of past experiences (Penfield and Perot, 1963). We hypothesized that this effect could be used to modulate memory processing. Recent attempts at memory enhancement in the human brain have been focused on the hippocampus and other mesial temporal lobe structures, with a few reports of memory improvement in small studies of individual brain regions. Here, we investigated the effect of stimulation in four brain regions known to support declarative memory: hippocampus, parahippocampal neocortex, prefrontal cortex and temporal cortex. Intracranial electrode recordings with stimulation were used to assess verbal memory performance in a group of 22 patients (nine males). We show enhanced performance with electrical stimulation in the lateral temporal cortex (paired t-test, P = 0.0067), but not in the other brain regions tested. This selective enhancement was observed both on the group level, and for two of the four individual subjects stimulated in the temporal cortex. This study shows that electrical stimulation in specific brain areas can enhance verbal memory performance in humans.awx373media15704855796001.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19028626
003      
CZ-PrNML
005      
20190822084847.0
007      
ta
008      
190813s2018 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1093/brain/awx373 $2 doi
035    __
$a (PubMed)29324988
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Kucewicz, Michal T $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
245    10
$a Evidence for verbal memory enhancement with electrical brain stimulation in the lateral temporal cortex / $c MT. Kucewicz, BM. Berry, LR. Miller, F. Khadjevand, Y. Ezzyat, JM. Stein, V. Kremen, BH. Brinkmann, P. Wanda, MR. Sperling, R. Gorniak, KA. Davis, BC. Jobst, RE. Gross, B. Lega, J. Van Gompel, SM. Stead, DS. Rizzuto, MJ. Kahana, GA. Worrell,
520    9_
$a Direct electrical stimulation of the human brain can elicit sensory and motor perceptions as well as recall of memories. Stimulating higher order association areas of the lateral temporal cortex in particular was reported to activate visual and auditory memory representations of past experiences (Penfield and Perot, 1963). We hypothesized that this effect could be used to modulate memory processing. Recent attempts at memory enhancement in the human brain have been focused on the hippocampus and other mesial temporal lobe structures, with a few reports of memory improvement in small studies of individual brain regions. Here, we investigated the effect of stimulation in four brain regions known to support declarative memory: hippocampus, parahippocampal neocortex, prefrontal cortex and temporal cortex. Intracranial electrode recordings with stimulation were used to assess verbal memory performance in a group of 22 patients (nine males). We show enhanced performance with electrical stimulation in the lateral temporal cortex (paired t-test, P = 0.0067), but not in the other brain regions tested. This selective enhancement was observed both on the group level, and for two of the four individual subjects stimulated in the temporal cortex. This study shows that electrical stimulation in specific brain areas can enhance verbal memory performance in humans.awx373media15704855796001.
650    _2
$a dospělí $7 D000328
650    _2
$a mapování mozku $7 D001931
650    _2
$a hluboká mozková stimulace $x metody $7 D046690
650    _2
$a epilepsie $x komplikace $7 D004827
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a poruchy paměti $x etiologie $x terapie $7 D008569
650    _2
$a lidé středního věku $7 D008875
650    _2
$a spánkový lalok $x fyziologie $7 D013702
650    _2
$a časové faktory $7 D013997
650    _2
$a verbální učení $x fyziologie $7 D014706
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
655    _2
$a Research Support, U.S. Gov't, Non-P.H.S. $7 D013486
655    _2
$a audiovizuální média $7 D059040
700    1_
$a Berry, Brent M $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
700    1_
$a Miller, Laura R $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
700    1_
$a Khadjevand, Fatemeh $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
700    1_
$a Ezzyat, Youssef $u University of Pennsylvania, Department of Psychology, Philadelphia PA, USA.
700    1_
$a Stein, Joel M $u University of Pennsylvania Hospital, Department of Radiology, Philadelphia PA, USA.
700    1_
$a Kremen, Vaclav $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA. Czech Technical University, Czech Institute of Informatics, Robotics and Cybernetics, Prague, Czech Republic.
700    1_
$a Brinkmann, Benjamin H $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
700    1_
$a Wanda, Paul $u University of Pennsylvania, Department of Psychology, Philadelphia PA, USA.
700    1_
$a Sperling, Michael R $u Thomas Jefferson University Hospital, Department of Neurology, Philadelphia PA, USA.
700    1_
$a Gorniak, Richard $u Thomas Jefferson University Hospital, Department of Radiology, Philadelphia PA, USA.
700    1_
$a Davis, Kathryn A $u University of Pennsylvania Hospital, Department of Neurology, Philadelphia PA, USA.
700    1_
$a Jobst, Barbara C $u Dartmouth-Hitchcock Medical Center, Department of Neurology, Lebanon NH, USA.
700    1_
$a Gross, Robert E $u Emory University, Department of Neurosurgery, Atlanta GA, USA.
700    1_
$a Lega, Bradley $u UT Southwestern Medical Center, Department of Neurosurgery, Dallas TX, USA.
700    1_
$a Van Gompel, Jamie $u Mayo Clinic, Department of Neurosurgery, Rochester MN, USA.
700    1_
$a Stead, S Matt $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
700    1_
$a Rizzuto, Daniel S $u University of Pennsylvania, Department of Psychology, Philadelphia PA, USA.
700    1_
$a Kahana, Michael J $u University of Pennsylvania, Department of Psychology, Philadelphia PA, USA.
700    1_
$a Worrell, Gregory A $u Mayo Clinic, Department of Neurology, Rochester MN, USA. Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester MN, USA.
773    0_
$w MED00009356 $t Brain : a journal of neurology $x 1460-2156 $g Roč. 141, č. 4 (2018), s. 971-978
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29324988 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20190813 $b ABA008
991    __
$a 20190822085125 $b ABA008
999    __
$a ok $b bmc $g 1433775 $s 1067086
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 141 $c 4 $d 971-978 $e 20180401 $i 1460-2156 $m Brain $n Brain $x MED00009356
LZP    __
$a Pubmed-20190813

Find record

Citation metrics

Archiving options