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Characterization of KPC-Encoding Plasmids from Enterobacteriaceae Isolated in a Czech Hospital

R. Kukla, K. Chudejova, CC. Papagiannitsis, M. Medvecky, K. Habalova, L. Hobzova, R. Bolehovska, L. Pliskova, J. Hrabak, H. Zemlickova,

. 2018 ; 62 (3) : . [pub] 20180223

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc19028660

Grantová podpora
NV15-28663A MZ0 CEP - Centrální evidence projektů
NV17-29239A MZ0 CEP - Centrální evidence projektů

Ten Enterobacteriaceae isolates collected in a Czech hospital carried blaKPC-positive plasmids of different sizes (∼30, ∼45, and ∼80 kb). Sequencing revealed three types of plasmids (A to C) with the Tn4401a transposon. Type A plasmids comprised an IncR backbone and a KPC-2-encoding multidrug resistance (MDR) region. Type B plasmids were derivatives of type A plasmids carrying an IncN3-like segment, while type C plasmids were IncP6 plasmids sharing the same KPC-2-encoding MDR region with type A and B plasmids.

Citace poskytuje Crossref.org

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$a Ten Enterobacteriaceae isolates collected in a Czech hospital carried blaKPC-positive plasmids of different sizes (∼30, ∼45, and ∼80 kb). Sequencing revealed three types of plasmids (A to C) with the Tn4401a transposon. Type A plasmids comprised an IncR backbone and a KPC-2-encoding multidrug resistance (MDR) region. Type B plasmids were derivatives of type A plasmids carrying an IncN3-like segment, while type C plasmids were IncP6 plasmids sharing the same KPC-2-encoding MDR region with type A and B plasmids.
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$a Chudejova, Katerina $u Department of Microbiology, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic. Biomedical Center, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
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$a Medvecky, Matej $u Veterinary Research Institute, Brno, Czech Republic. National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno, Czech Republic.
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$a Habalova, Katerina $u Department of Clinical Microbiology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
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$a Pliskova, Lenka $u Department of Clinical Biochemistry and Diagnostics, University Hospital, Hradec Kralove, Czech Republic.
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$a Hrabak, Jaroslav $u Department of Microbiology, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic. Biomedical Center, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
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$a Zemlickova, Helena $u Department of Clinical Microbiology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic. National Reference Laboratory for Antibiotics, National Institute of Public Health, Prague, Czech Republic.
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