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Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS

S. Pataridis, O. Romanov, I. Mikšík,

. 2019 ; 42 (4) : 797-808. [pub] 20190121

Jazyk angličtina Země Německo

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc19034849

Grantová podpora
17-10832S Czech Science Foundation
RVO: 67985823 Czech Academy of Sciences

Saiga horn extracts were analyzed with the goal of obtaining new information about compounds present in it. The purpose of this study is to find synthetic alternatives to Saiga horn extract, which is used in traditional Chinese medicine, by identifying potentially biologically active compounds in the extracts. Using high-performance liquid chromatography coupled with high-resolution mass spectrometry, we have been able to identify a series of short-chain polyhydroxybutyrates in alcoholic extracts of Saiga horn. Optimized high-performance liquid chromatography coupled with tandem mass spectrometry methods for analysis of short-chain poly-3-hydroxybutyrates were developed and subsequently applied to investigate Saiga horn extract for the presence of these compounds, which might explain its biological actions, particularly for its antipyretic and procoagulant properties.

Citace poskytuje Crossref.org

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