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Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

Z. Kahounová, E. Slabáková, L. Binó, J. Remšík, R. Fedr, J. Bouchal, D. Kurfűrstová, R. Vrtěl, V. Študent, L. Jurečková, V. Porokh, A. Hampl, K. Souček,

. 2018 ; 33 (-) : 255-259. [pub] 20181116

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu kazuistiky, časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc19034883

Grantová podpora
NV15-28628A MZ0 CEP - Centrální evidence projektů

A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5TM Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.

Citace poskytuje Crossref.org

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$a Slabáková, Eva $u Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic.
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