-
Something wrong with this record ?
Genetic diversity of PRRSV 1 in Central Eastern Europe in 1994-2014: origin and evolution of the virus in the region
G. Balka, K. Podgórska, MS. Brar, Á. Bálint, D. Cadar, V. Celer, L. Dénes, Z. Dirbakova, A. Jedryczko, L. Márton, D. Novosel, T. Petrović, I. Sirakov, D. Szalay, I. Toplak, FC. Leung, T. Stadejek,
Language English Country Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
Directory of Open Access Journals
from 2011
Free Medical Journals
from 2011
PubMed Central
from 2011
Europe PubMed Central
from 2011
ProQuest Central
from 2011-01-01 to 2019-12-31
Open Access Digital Library
from 2011-01-01
Open Access Digital Library
from 2011-01-01
Health & Medicine (ProQuest)
from 2011-01-01 to 2019-12-31
ROAD: Directory of Open Access Scholarly Resources
from 2011
Springer Nature OA/Free Journals
from 2011-12-01
Springer Nature - nature.com Journals - Fully Open Access
from 2011-12-01
- MeSH
- DNA, Viral chemistry MeSH
- Phylogeny MeSH
- Phylogeography MeSH
- Genetic Variation MeSH
- Evolution, Molecular MeSH
- Porcine respiratory and reproductive syndrome virus genetics MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Europe, Eastern MeSH
More than 20 years after the first outbreaks, the phylogenetic picture of PRRSV is still incomplete and full of gaps, especially in regards of PRRSV 1. Due to the exceptional diversity observed at the eastern borders of Europe and the low number of available sequences from Central Eastern European countries, the authors collected and analyzed both recent as well as already submitted sequences comparing them to a large backbone set of available ORF5 sequences representing the full spectrum of PRRSV 1 Subtype 1 diversity to conduct a systematic phylogenetic analysis and reclassification elucidating the diversity of the virus in these countries. Moreover, further analyses of the EUROSTAT data regarding the live pig movement trends revealed their influence of virus diversity and evolution. The results indicate that besides the effect of local, isolated divergent evolution and the use of modified live vaccines, the most important factor influencing a given country's virus diversity is the transboundary movement of live, infected animals.
Department of Pathology University of Veterinary Medicine István Str 2 H 1076 Budapest Hungary
National Veterinary Research Institute Partyzantów 57 24 100 Pulawy Poland
Scientific Veterinary Institute ''Novi Sad Rumenački put 20 21000 Novi Sad Serbia
The University of Hong Kong 5N 12 Kadoorie Biological Science Building Hong Kong China
Veterinary Diagnostic Laboratory Ostródzka 11 036 Gietrzwałd Poland
Veterinary Institute Zvolen Pod Drahami 918 960 86 Zvolen Slovak Republic
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19045454
- 003
- CZ-PrNML
- 005
- 20200113082233.0
- 007
- ta
- 008
- 200109s2018 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1038/s41598-018-26036-w $2 doi
- 035 __
- $a (PubMed)29773820
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a Balka, Gyula $u Department of Pathology, University of Veterinary Medicine, István Str. 2, H-1076, Budapest, Hungary. balka.gyula@univet.hu.
- 245 10
- $a Genetic diversity of PRRSV 1 in Central Eastern Europe in 1994-2014: origin and evolution of the virus in the region / $c G. Balka, K. Podgórska, MS. Brar, Á. Bálint, D. Cadar, V. Celer, L. Dénes, Z. Dirbakova, A. Jedryczko, L. Márton, D. Novosel, T. Petrović, I. Sirakov, D. Szalay, I. Toplak, FC. Leung, T. Stadejek,
- 520 9_
- $a More than 20 years after the first outbreaks, the phylogenetic picture of PRRSV is still incomplete and full of gaps, especially in regards of PRRSV 1. Due to the exceptional diversity observed at the eastern borders of Europe and the low number of available sequences from Central Eastern European countries, the authors collected and analyzed both recent as well as already submitted sequences comparing them to a large backbone set of available ORF5 sequences representing the full spectrum of PRRSV 1 Subtype 1 diversity to conduct a systematic phylogenetic analysis and reclassification elucidating the diversity of the virus in these countries. Moreover, further analyses of the EUROSTAT data regarding the live pig movement trends revealed their influence of virus diversity and evolution. The results indicate that besides the effect of local, isolated divergent evolution and the use of modified live vaccines, the most important factor influencing a given country's virus diversity is the transboundary movement of live, infected animals.
- 650 _2
- $a DNA virů $x chemie $7 D004279
- 650 _2
- $a molekulární evoluce $7 D019143
- 650 _2
- $a genetická variace $7 D014644
- 650 _2
- $a fylogeneze $7 D010802
- 650 _2
- $a fylogeografie $7 D058974
- 650 _2
- $a virus reprodukčního a respiračního syndromu prasat $x genetika $7 D019316
- 651 _2
- $a východní Evropa $7 D005061
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Podgórska, Katarzyna $u National Veterinary Research Institute, Partyzantów 57, 24-100, Pulawy, Poland.
- 700 1_
- $a Brar, Manreetpal Singh $u The University of Hong Kong, 5N-12, Kadoorie Biological Science Building, Hong Kong, China.
- 700 1_
- $a Bálint, Ádám $u National Food Chain Safety Office Veterinary Diagnostic Directorate, Tábornok Str. 2, H-1149, Budapest, Hungary.
- 700 1_
- $a Cadar, Daniel $u Arbovirology, Bernhard Nocht Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research National Reference Centre for Tropical Infectious Diseases, Bernhard Nocht Strasse 74, 20359, Hamburg, Germany.
- 700 1_
- $a Celer, Vladimir $u Faculty of Veterinary Medicine, Institute of Infectious Diseases and Microbiology, University of Veterinary and Pharmaceutical Sciences Brno, 612 42, Brno, Czech Republic.
- 700 1_
- $a Dénes, Lilla $u Department of Pathology, University of Veterinary Medicine, István Str. 2, H-1076, Budapest, Hungary.
- 700 1_
- $a Dirbakova, Zuzana $u Veterinary Institute Zvolen, Pod Drahami 918, 960 86, Zvolen, Slovak Republic.
- 700 1_
- $a Jedryczko, Anna $u Veterinary Diagnostic Laboratory, Ostródzka, 11-036, Gietrzwałd, Poland.
- 700 1_
- $a Márton, Lázár $u National Food Chain Safety Office Animal Health and Animal Welfare Directorate, Keleti Károly Str. 24, H-1024, Budapest, Hungary.
- 700 1_
- $a Novosel, Dinko $u University of Zagreb, Faculty of Agriculture, Department of Animal Science, Svetošimunska cesta 25, 10000, Zagreb, Croatia.
- 700 1_
- $a Petrović, Tamaš $u Scientific Veterinary Institute ''Novi Sad" Rumenački put 20, 21000, Novi Sad, Serbia.
- 700 1_
- $a Sirakov, Ivo $u Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia, Zdrave Str. 2, 1431, Sofia, Bulgaria.
- 700 1_
- $a Szalay, Dóra $u National Food Chain Safety Office Veterinary Diagnostic Directorate, Tábornok Str. 2, H-1149, Budapest, Hungary.
- 700 1_
- $a Toplak, Ivan $u University of Ljubljana, Veterinary Faculty, National Veterinary Institute Gerbičeva, 60, 1000, Ljubljana, Slovenia.
- 700 1_
- $a Leung, Frederick Chi-Ching $u The University of Hong Kong, 5N-12, Kadoorie Biological Science Building, Hong Kong, China.
- 700 1_
- $a Stadejek, Tomasz $u Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, ul. Nowoursynowska 159c, 02-776, Warsaw, Poland.
- 773 0_
- $w MED00182195 $t Scientific reports $x 2045-2322 $g Roč. 8, č. 1 (2018), s. 7811
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/29773820 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20200109 $b ABA008
- 991 __
- $a 20200113082604 $b ABA008
- 999 __
- $a ok $b bmc $g 1483723 $s 1084127
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2018 $b 8 $c 1 $d 7811 $e 20180517 $i 2045-2322 $m Scientific reports $n Sci Rep $x MED00182195
- LZP __
- $a Pubmed-20200109
