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Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries
AM. Vicedo-Cabrera, F. Sera, C. Liu, B. Armstrong, A. Milojevic, Y. Guo, S. Tong, E. Lavigne, J. Kyselý, A. Urban, H. Orru, E. Indermitte, M. Pascal, V. Huber, A. Schneider, K. Katsouyanni, E. Samoli, M. Stafoggia, M. Scortichini, M. Hashizume,...
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, multicentrická studie, práce podpořená grantem
Grantová podpora
MR/M022625/1
Medical Research Council - United Kingdom
MR/R013349/1
Medical Research Council - United Kingdom
NLK
Europe PubMed Central
od 1981
ProQuest Central
od 1996-01-01
Nursing & Allied Health Database (ProQuest)
od 1996-01-01
Health & Medicine (ProQuest)
od 1996-01-01
PubMed
32041707
DOI
10.1136/bmj.m108
Knihovny.cz E-zdroje
- MeSH
- celosvětové zdraví statistika a číselné údaje MeSH
- environmentální politika MeSH
- klimatické změny mortalita MeSH
- lidé MeSH
- mezinárodní spolupráce MeSH
- mortalita * MeSH
- ozon škodlivé účinky analýza MeSH
- roční období MeSH
- velkoměsta MeSH
- vystavení vlivu životního prostředí škodlivé účinky normy MeSH
- znečištění ovzduší škodlivé účinky analýza MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- velkoměsta MeSH
OBJECTIVE: To assess short term mortality risks and excess mortality associated with exposure to ozone in several cities worldwide. DESIGN: Two stage time series analysis. SETTING: 406 cities in 20 countries, with overlapping periods between 1985 and 2015, collected from the database of Multi-City Multi-Country Collaborative Research Network. POPULATION: Deaths for all causes or for external causes only registered in each city within the study period. MAIN OUTCOME MEASURES: Daily total mortality (all or non-external causes only). RESULTS: A total of 45 165 171 deaths were analysed in the 406 cities. On average, a 10 µg/m3 increase in ozone during the current and previous day was associated with an overall relative risk of mortality of 1.0018 (95% confidence interval 1.0012 to 1.0024). Some heterogeneity was found across countries, with estimates ranging from greater than 1.0020 in the United Kingdom, South Africa, Estonia, and Canada to less than 1.0008 in Mexico and Spain. Short term excess mortality in association with exposure to ozone higher than maximum background levels (70 µg/m3) was 0.26% (95% confidence interval 0.24% to 0.28%), corresponding to 8203 annual excess deaths (95% confidence interval 3525 to 12 840) across the 406 cities studied. The excess remained at 0.20% (0.18% to 0.22%) when restricting to days above the WHO guideline (100 µg/m3), corresponding to 6262 annual excess deaths (1413 to 11 065). Above more lenient thresholds for air quality standards in Europe, America, and China, excess mortality was 0.14%, 0.09%, and 0.05%, respectively. CONCLUSIONS: Results suggest that ozone related mortality could be potentially reduced under stricter air quality standards. These findings have relevance for the implementation of efficient clean air interventions and mitigation strategies designed within national and international climate policies.
Department of Environmental Health Harvard T H Chan School of Public Health Boston MA USA
Department of Environmental Health National Institute of Public Health Cuernavaca Morelos Mexico
Department of Environmental Health Rollins School of Public Health Emory University Atlanta USA
Department of Epidemiology Instituto Nacional de Saúde Dr Ricardo Jorge Lisbon Portugal
Department of Epidemiology Lazio Regional Health Service ASL Roma 1 Rome Italy
Department of Public Health and Clinical Medicine Umeå University Umeå Sweden
Environmental and Occupational Medicine National Taiwan University and NTU Hospital Taiwan
Faculty of Health and Sport Sciences University of Tsukuba Tsukuba Japan
Institute of Atmospheric Physics Czech Academy of Sciences Prague Czech Republic
Institute of Family Medicine and Public Health University of Tartu Tartu Estonia
Santé Publique France French National Public Health Agency Saint Maurice France
School of Forestry and Environmental Studies Yale University New Haven CT USA
School of Tropical Medicine and Global Health Nagasaki University Nagasaki Japan
Swiss Tropical and Public Health Institute Basel Switzerland University of Basel Basel Switzerland
Citace poskytuje Crossref.org
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- $a Vicedo-Cabrera, Ana M $u Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London WC1H 9SH, UK ana.vicedo-cabrera@lshtm.ac.uk. Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland. Oeschger Centre for Climate Change Research, University of Bern, Bern, Switzerland.
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- $a Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries / $c AM. Vicedo-Cabrera, F. Sera, C. Liu, B. Armstrong, A. Milojevic, Y. Guo, S. Tong, E. Lavigne, J. Kyselý, A. Urban, H. Orru, E. Indermitte, M. Pascal, V. Huber, A. Schneider, K. Katsouyanni, E. Samoli, M. Stafoggia, M. Scortichini, M. Hashizume, Y. Honda, CFS. Ng, M. Hurtado-Diaz, J. Cruz, S. Silva, J. Madureira, N. Scovronick, RM. Garland, H. Kim, A. Tobias, C. Íñiguez, B. Forsberg, C. Åström, MS. Ragettli, M. Röösli, YL. Guo, BY. Chen, A. Zanobetti, J. Schwartz, ML. Bell, H. Kan, A. Gasparrini,
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- $a OBJECTIVE: To assess short term mortality risks and excess mortality associated with exposure to ozone in several cities worldwide. DESIGN: Two stage time series analysis. SETTING: 406 cities in 20 countries, with overlapping periods between 1985 and 2015, collected from the database of Multi-City Multi-Country Collaborative Research Network. POPULATION: Deaths for all causes or for external causes only registered in each city within the study period. MAIN OUTCOME MEASURES: Daily total mortality (all or non-external causes only). RESULTS: A total of 45 165 171 deaths were analysed in the 406 cities. On average, a 10 µg/m3 increase in ozone during the current and previous day was associated with an overall relative risk of mortality of 1.0018 (95% confidence interval 1.0012 to 1.0024). Some heterogeneity was found across countries, with estimates ranging from greater than 1.0020 in the United Kingdom, South Africa, Estonia, and Canada to less than 1.0008 in Mexico and Spain. Short term excess mortality in association with exposure to ozone higher than maximum background levels (70 µg/m3) was 0.26% (95% confidence interval 0.24% to 0.28%), corresponding to 8203 annual excess deaths (95% confidence interval 3525 to 12 840) across the 406 cities studied. The excess remained at 0.20% (0.18% to 0.22%) when restricting to days above the WHO guideline (100 µg/m3), corresponding to 6262 annual excess deaths (1413 to 11 065). Above more lenient thresholds for air quality standards in Europe, America, and China, excess mortality was 0.14%, 0.09%, and 0.05%, respectively. CONCLUSIONS: Results suggest that ozone related mortality could be potentially reduced under stricter air quality standards. These findings have relevance for the implementation of efficient clean air interventions and mitigation strategies designed within national and international climate policies.
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- $a Lavigne, Eric $u Air Health Science Division, Health Canada, Ottawa, Canada. School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.
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