This manuscript is an accompanying resource of the original research article entitled "Child development at 6 years after maternal cancer diagnosis and treatment during pregnancy" and present data that compare the outcome of 6-year-old-children born to women diagnosed with cancer during pregnancy (with or without treatment during pregnancy) (study group) with children born after an uncomplicated pregnancy (control group). Oncological, obstetrical and neonatal data were collected. Neurodevelopment was examined by clinical evaluation and neuropsychological testing (including intelligence, attention and memory tests) and by general health and behavior questionnaires. Cardiac evaluation included electro- and echocardiography. Univariate analyses of covariance were used to investigate between-group differences. A subgroup analysis was performed in chemotherapy-exposed children versus controls and anthracycline-exposed versus controls. Additionally, the incidence of behaviour problems was compared to matched controls for children whose mothers died and for those with surviving mothers.

Center for Gynecologic Oncology Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam the Netherlands Department of Oncology KU Leuven Leuven Belgium Department of Obstetrics and Gynecology Amsterdam UMC Location Amsterdam Medical Center and University of Amsterdam the Netherlands

Center for Gynecologic Oncology Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam the Netherlands Princess Máxima Center for pediatric oncology Utrecht the Netherlands

Clinic of Obstetrics and Gynecology University of Milan Bicocca and San Gerardo Hospital Monza Italy

Department of Cardiology The Hospital for Sick Children University of Toronto Toronto ON Canada

Department of Cardiology University Hospitals Leuven Leuven Belgium

Department of Internal Medicine Radboud UMC Nijmegen the Netherlands

Department of Neonatology University Hospitals Leuven Leuven Belgium

Department of Obstetrics and Gynecology 3rd Medical Faculty Charles University Faculty Hospital Kralovske Vinohrady Prague Czech Republic

Department of Obstetrics and Gynecology Amsterdam UMC Location VU University Medical Center the Netherlands

Department of Obstetrics and Gynecology University Hospitals Leuven Department of Development and Regeneration KU Leuven Leuven Belgium

Department of Obstetrics and Gynecology University Hospitals Leuven Department of Oncology KU Leuven Leuven Belgium

Department of Obstetrics Cliniques Universitaires St Luc Brussels Belgium

Department of Pediatrics University Hospitals Leuven Leuven Belgium

Department of Public Health and Primary Care Faculty of Medicine KU Leuven Leuven and Data Scientist Knowledge Center SD Worx Antwerp Belgium

Faculty of Psychology and Educational Sciences KU Leuven Leuven Belgium

Neonatal Intensive Care Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Department of Clinical Sciences and Community Health University of Milan Milan Italy

Princess Máxima Center for pediatric oncology Utrecht the Netherlands

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