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Subsequent Event Risk in Individuals With Established Coronary Heart Disease
RS. Patel, V. Tragante, AF. Schmidt, RO. McCubrey, MV. Holmes, LJ. Howe, K. Direk, A. Åkerblom, K. Leander, SS. Virani, KA. Kaminski, JD. Muehlschlegel, H. Allayee, P. Almgren, M. Alver, EV. Baranova, H. Behloui, B. Boeckx, PS. Braund, LP....
Language English Country United States
Document type Journal Article, Meta-Analysis, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
Grant support
PG/18/50/33837
British Heart Foundation - United Kingdom
PG/18/5033837
British Heart Foundation - United Kingdom
U01 GM074492
NIGMS NIH HHS - United States
Department of Health - United Kingdom
085475/B/08/Z
Wellcome Trust - United Kingdom
R56 HL126558
NHLBI NIH HHS - United States
084727/Z/08/Z
Wellcome Trust - United Kingdom
Medical Research Council - United Kingdom
P50 HL077113
NHLBI NIH HHS - United States
335122
European Research Council - International
RG/14/5/30893
British Heart Foundation - United Kingdom
R01 ES025786
NIEHS NIH HHS - United States
072960/Z/03/Z
Wellcome Trust - United Kingdom
085475/Z/08/Z
Wellcome Trust - United Kingdom
R01 NR013396
NINR NIH HHS - United States
FS/14/76/30933
British Heart Foundation - United Kingdom
084726/Z/08/Z
Wellcome Trust - United Kingdom
P01 ES022845
NIEHS NIH HHS - United States
FS/18/23/33512
British Heart Foundation - United Kingdom
PCL 17/07
Chief Scientist Office - United Kingdom
P01 HL101398
NHLBI NIH HHS - United States
P01 HL076491
NHLBI NIH HHS - United States
PCL/17/07
Chief Scientist Office - United Kingdom
R01 HL074730
NHLBI NIH HHS - United States
CIHR - Canada
R01 HL133169
NHLBI NIH HHS - United States
- MeSH
- Adult MeSH
- Coronary Disease pathology MeSH
- Smoking MeSH
- Middle Aged MeSH
- Humans MeSH
- Prognosis MeSH
- Proportional Hazards Models MeSH
- Risk Factors MeSH
- Aged MeSH
- Sex Factors MeSH
- Age Factors MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Meta-Analysis MeSH
- Research Support, Non-U.S. Gov't MeSH
- Research Support, N.I.H., Extramural MeSH
BACKGROUND: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD. METHODS: The consortium currently includes 57 studies from 18 countries, recruiting 185 614 participants with either acute coronary syndrome, stable CHD, or a mixture of both at baseline. All studies collected biological samples and followed-up study participants prospectively for subsequent events. RESULTS: Enrollment into the individual studies took place between 1985 to present day with a duration of follow-up ranging from 9 months to 15 years. Within each study, participants with CHD are predominantly of self-reported European descent (38%-100%), mostly male (44%-91%) with mean ages at recruitment ranging from 40 to 75 years. Initial feasibility analyses, using a federated analysis approach, yielded expected associations between age (hazard ratio, 1.15; 95% CI, 1.14-1.16) per 5-year increase, male sex (hazard ratio, 1.17; 95% CI, 1.13-1.21) and smoking (hazard ratio, 1.43; 95% CI, 1.35-1.51) with risk of subsequent CHD death or myocardial infarction and differing associations with other individual and composite cardiovascular endpoints. CONCLUSIONS: GENIUS-CHD is a global collaboration seeking to elucidate genetic and nongenetic determinants of subsequent event risk in individuals with established CHD, to improve residual risk prediction and identify novel drug targets for secondary prevention. Initial analyses demonstrate the feasibility and reliability of a federated analysis approach. The consortium now plans to initiate and test novel hypotheses as well as supporting replication and validation analyses for other investigators.
5th Department of Medicine Medical Faculty Mannheim Heidelberg University Germany
Amsterdam UMC University of Amsterdam Clinical Epidemiology and Biostatistics The Netherlands
Assistance Publique Hôpitaux de Paris
ATS Sardegna ASL 3 Nuoro Nuoro Italy
Cardiology Centre Institute for Clinical and Experimental Medicine Prague Czech Republic
Cardiology Department Parma University Hospital Italy
Centre de recherche de l'Institut Universitaire de cardiologie et de pneumologie de Québec Canada
Centro de Pesquisa Clinica Hospital Universitario Universidade de Sao Paulo São Paulo Brazil
Clinica Mediterranea Naples Italy
CNR Institute of Clinical Physiology Pisa
Department of Anesthesiology Perioperative and Pain Medicine Brigham and Women's Hospital Boston MA
Department of Biostatistics and Epidemiology Texas Heart Institute Houston
Department of Cardio Thoracic Surgery University of Tampere Finland
Department of Cardiology and Internal Diseases Military Institute of Medicine Warsaw Poland
Department of Cardiology Clinical Sciences Lund University Skåne University Hospital
Department of Cardiology Erasmus MC Thoraxcenter
Department of Cardiology Herlev and Gentofte Hospital Hellerup Denmark
Department of Cardiology Medical University of Bialystok Poland
Department of Cardiology Tampere University Hospital Finland
Department of Cardiology The Heart Centre Copenhagen University Hospital Rigshospitalet
Department of Cardiology Uppsala Clinical Research Centre Uppsala University Sweden
Department of Cardiovascular Medicine Humanitas Clinical and Research Centre Milan Italy
Department of Cardiovascular Medicine University of Münster Germany
Department of Cardiovascular Sciences Katholieke Universiteit Leuven Belgium
Department of Cellular and Molecular Medicine Lerner Research Institute Cleveland Clinic OH
Department of Clinical Biochemistry Copenhagen University Hospital Gentofte
Department of Clinical Chemistry
Department of Clinical Chemistry and Hematology UMC Utrecht the Netherlands
Department of Clinical Chemistry UMC Utrecht the Netherlands
Department of Clinical Physiology Tampere University Hospital Finland
Department of Clinical Sciences Lund University Malmö Sweden
Department of Forensic Medicine
Department of Health Sciences University of Leicester United Kingdom
Department of Internal Medicine Jagiellonian University Medical College Kraków Poland
Department of Medical Genetics Medical University of Warsaw Poland
Department of Medicine University of Verona Italy
Department of Pathology and Molecular Medicine McMaster University
Department of Vascular Medicine Academic Medical Centre Amsterdam
Department of Vascular Medicine UMC Utrecht Utrecht University the Netherlands
Division Heart and Lungs Department of Cardiology UMC Utrecht University of Utrecht the Netherlands
Division of Cardiovascular Medicine College of Medicine University of Florida Gainesville
Division of Clinical Epidemiology and Aging Research German Cancer Research Center
Division of Heart and Lungs Department of Cardiology UMC Utrecht the Netherlands
Division of Pharmacoepidemiology and Clinical Pharmacology Utrecht University the Netherlands
first Chair and Department of Cardiology Medical University of Warsaw Poland
Harvard Medical School Boston MA
Heart and Lung Centre Helsinki University Hospital and University of Helsinki Finland
Heart Health Research Group University of Auckland New Zealand
Heart Institute University of Sao Paulo Brazil
Institute for Genetic Medicine Keck School of Medicine of USC Los Angeles CA
Institute for Medical Informatics Statistics and Epidemiology University of Leipzig Germany
Institute of Cardiovascular and Medical Sciences University of Glasgow United Kingdom
Institute of Cardiovascular Science
Institute of Cardiovascular Science UMC Utrecht the Netherlands
Institute of Environmental Medicine Karolinska Institute Stockholm Sweden
Institute of Health Informatics
Intermountain Heart Institute Intermountain Medical Center Salt Lake City UT
Julius Center for Health Sciences and Primary Care UMC Utrecht Utrecht University the Netherlands
Laboratory for Translational Genetics Department of Human Genetics
Laboratory of Experimental Cardiology UMC Utrecht the Netherlands
Laval University Institute universitaire de cardiologie et de pneumologie de Québec Canada
LIFE Research Centre for Civilization Diseases
Medical University of Bialystok
Montreal Heart Institute OC Canada
QMRI Cardiovascular Sciences University of Edinburgh United Kingdom
Research Institute of the McGill University Health Centre Montreal QC Canada
Respiratory Oncology Unit Department of Respiratory Medicine University Hospitals KU Leuven Belgium
Robertson Centre for Biostatistics University of Glasgow United Kingdom
Saint Luke's Mid America Heart Institute University of Missouri Kansas City
Section of Cardiology Michael E DeBakey Veterans Affairs Medical Center Houston TX
Section of Cardiovascular Research Department of Medicine Baylor College of Medicine Houston TX
St Antonius Hospital Department Cardiology Nieuwegein the Netherlands
The Christchurch Heart Institute University of Otago Christchurch New Zealand
The University of Edinburgh United Kingdom
Transplantation Laboratory Helsinki University Hospital and University of Helsinki Finland
University Medical Centre University of Groningen the Netherlands
University of Texas School of Public Health Houston
Uppsala Clinical Research Center Sweden
Uppsala Clinical Research Center Sweden Uppsala University Sweden
Vorarlberg Institute for Vascular Investigation and Treatment
References provided by Crossref.org
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- 520 9_
- $a BACKGROUND: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD. METHODS: The consortium currently includes 57 studies from 18 countries, recruiting 185 614 participants with either acute coronary syndrome, stable CHD, or a mixture of both at baseline. All studies collected biological samples and followed-up study participants prospectively for subsequent events. RESULTS: Enrollment into the individual studies took place between 1985 to present day with a duration of follow-up ranging from 9 months to 15 years. Within each study, participants with CHD are predominantly of self-reported European descent (38%-100%), mostly male (44%-91%) with mean ages at recruitment ranging from 40 to 75 years. Initial feasibility analyses, using a federated analysis approach, yielded expected associations between age (hazard ratio, 1.15; 95% CI, 1.14-1.16) per 5-year increase, male sex (hazard ratio, 1.17; 95% CI, 1.13-1.21) and smoking (hazard ratio, 1.43; 95% CI, 1.35-1.51) with risk of subsequent CHD death or myocardial infarction and differing associations with other individual and composite cardiovascular endpoints. CONCLUSIONS: GENIUS-CHD is a global collaboration seeking to elucidate genetic and nongenetic determinants of subsequent event risk in individuals with established CHD, to improve residual risk prediction and identify novel drug targets for secondary prevention. Initial analyses demonstrate the feasibility and reliability of a federated analysis approach. The consortium now plans to initiate and test novel hypotheses as well as supporting replication and validation analyses for other investigators.
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- 700 1_
- $a Tragante, Vinicius $u Division of Heart and Lungs, Department of Cardiology (V.T., A.F.S.,D.K.,F.W.A.), UMC Utrecht, the Netherlands.
- 700 1_
- $a Schmidt, Amand F $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom. Division of Heart and Lungs, Department of Cardiology (V.T., A.F.S.,D.K.,F.W.A.), UMC Utrecht, the Netherlands.
- 700 1_
- $a McCubrey, Raymond O $u Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (R.O.M., J.F.C., J.B.M., J.L.A., B.D.H).
- 700 1_
- $a Holmes, Michael V $u Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Medical Research Council Population Health Research Unit, University of Oxford, United Kingdom (M.V.H). National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital, United Kingdom (M.V.H.).
- 700 1_
- $a Howe, Laurence J $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom.
- 700 1_
- $a Direk, Kenan $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom.
- 700 1_
- $a Åkerblom, Axel $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Cardiology, Department of Medical Sciences (A. Åkerblom, C.H., D. Lindholm, S.J., B.L., L.W.), Uppsala University, Sweden.
- 700 1_
- $a Leander, Karin $u Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden (K.L., B.G., U.d.F.).
- 700 1_
- $a Virani, Salim S $u Section of Cardiology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX (S.S.V.). Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX (S.S.V., C.M.B.).
- 700 1_
- $a Kaminski, Karol A $u Department of Population Medicine and Civilization Disease Prevention (K.A.K.), Medical University of Bialystok, Poland. Department of Cardiology (K.A.K., A. Szpakowicz), Medical University of Bialystok, Poland.
- 700 1_
- $a Muehlschlegel, Jochen D $u Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA (J.D.M., M.H.). Harvard Medical School, Boston, MA (J.D.M., M.H., S.C.B).
- 700 1_
- $a Allayee, Hooman $u Departments of Preventive Medicine and Biochemistry and Molecular Medicine (H.A., J.H.), Keck School of Medicine of USC, Los Angeles, CA.
- 700 1_
- $a Almgren, Peter $u Department of Clinical Sciences, Lund University, Malmö, Sweden (P.A., O.M.).
- 700 1_
- $a Alver, Maris $u Estonian Genome Centre, Department of Biotechnology, Institute of Genomics, Institute of Molecular and Cell Biology, University of Tartu, Estonia (M.A., A.M.).
- 700 1_
- $a Baranova, Ekaterina V $u Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, the Netherlands (E.V.B., O.H.K., A.H.M.-v.d.Z.).
- 700 1_
- $a Behloui, Hassan $u Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada (H.B., L.D., L.P., G.T., J.M.B.).
- 700 1_
- $a Boeckx, Bram $u Laboratory for Translational Genetics, Department of Human Genetics (B.B., D. Lambrechts), Katholieke Universiteit Leuven, Belgium. Laboratory for Translational Genetics, VIB Center for Cancer Biology, Belgium (B.B., D. Lambrechts).
- 700 1_
- $a Braund, Peter S $u Department of Cardiovascular Sciences, BHF Cardiovascular Research Centre, University of Leicester, United Kingdom (P.S.B., C.P.N., N.J.S.). NIHR Leicester Biomedical Research Centre, Glenfield Hospital, United Kingdom (P.S.B., C.P.N., N.J.S.).
- 700 1_
- $a Breitling, Lutz P $u Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg (L.P.B., U.M.).
- 700 1_
- $a Delgado, Graciela $u Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (G.D., M. Kleber, W.M.).
- 700 1_
- $a Duarte, Nubia E $u Heart Institute, University of Sao Paulo, Brazil (N.E.D., A.C.P.).
- 700 1_
- $a Dubé, Marie-Pierre $u Montreal Heart Institute, OC, Canada (M.-P.D., J.-C.T.). Faculty of Medicine, Université de Montréal, QC, Canada (M.-P.D., J.-C.T.).
- 700 1_
- $a Dufresne, Line $u Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada (H.B., L.D., L.P., G.T., J.M.B.). Preventive and Genomic Cardiology, McGill University Health Centre, Montreal, QC, Canada (L.D., J.C.E., G.T.).
- 700 1_
- $a Eriksson, Niclas $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.).
- 700 1_
- $a Foco, Luisa $u Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, Italy (L.F.).
- 700 1_
- $a Scholz, Markus $u Institute for Medical Informatics, Statistics, and Epidemiology (M.S.), University of Leipzig, Germany. LIFE Research Centre for Civilization Diseases (M.S., A. Teren, R.B., J.T.), University of Leipzig, Germany.
- 700 1_
- $a Gijsberts, Crystel M $u Laboratory of Experimental Cardiology (C.M.G.), UMC Utrecht, the Netherlands.
- 700 1_
- $a Glinge, Charlotte $u Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet (C.G., T.E., R.J.). Amsterdam UMC, University of Amsterdam, Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, AMC Heart Center, the Netherlands (C.G., A.A.M.W., C.R.B.).
- 700 1_
- $a Gong, Yan $u Department of Pharmacotherapy and Translational Research, Centre for Pharmacogenomics (Y.G., R.M.C.-D., J.A.J.), University of Florida, Gainesville.
- 700 1_
- $a Hartiala, Jaana $u Institute for Genetic Medicine (J.H.), Keck School of Medicine of USC, Los Angeles, CA.
- 700 1_
- $a Heydarpour, Mahyar $u Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA (J.D.M., M.H.). Harvard Medical School, Boston, MA (J.D.M., M.H., S.C.B).
- 700 1_
- $a Hubacek, Jaroslav A $u Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic (J.A.H., J.P.).
- 700 1_
- $a Kleber, Marcus $u Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (G.D., M. Kleber, W.M.).
- 700 1_
- $a Kofink, Daniel $u Division of Heart and Lungs, Department of Cardiology (V.T., A.F.S.,D.K.,F.W.A.), UMC Utrecht, the Netherlands.
- 700 1_
- $a Kotti, Salma $u Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Clinical Pharmacology, Platform of Clinical Research of East Paris (URCEST-CRCEST-CRB HUEP-UPMC), France (S.K.).
- 700 1_
- $a Kuukasjärvi, Pekka $u Department of Cardio-Thoracic Surgery (P.K.), University of Tampere, Finland.
- 700 1_
- $a Lee, Vei-Vei $u Department of Biostatistics and Epidemiology, Texas Heart Institute, Houston (V.-V.L.).
- 700 1_
- $a Leiherer, Andreas $u Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria (A. Leiherer, C.H.S., H.D.). Private University of the Principality of Liechtenstein, Triesen (A. Leiherer, C.H.S., H.D.). Medical Central Laboratories, Feldkirch, Austria (A. Leiherer).
- 700 1_
- $a Lenzini, Petra A $u Statistical Genomics Division, Department of Genetics (P.A. Lenzini, S.C.), Washington University School of Medicine, Saint Louis, MO.
- 700 1_
- $a Levin, Daniel $u Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Scotland, United Kingdom (D. Levin, I.R.M., C.C.L.).
- 700 1_
- $a Lyytikäinen, Leo-Pekka $u Department of Clinical Chemistry (L.-P.L., T.L.), University of Tampere, Finland. Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., T.L.).
- 700 1_
- $a Martinelli, Nicola $u Department of Medicine, University of Verona, Italy (N.M., D.G., O.O.).
- 700 1_
- $a Mons, Ute $u Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg (L.P.B., U.M.).
- 700 1_
- $a Nelson, Christopher P $u Department of Cardiovascular Sciences, BHF Cardiovascular Research Centre, University of Leicester, United Kingdom (P.S.B., C.P.N., N.J.S.). NIHR Leicester Biomedical Research Centre, Glenfield Hospital, United Kingdom (P.S.B., C.P.N., N.J.S.).
- 700 1_
- $a Nikus, Kjell $u Department of Cardiology (K.N.), University of Tampere, Finland. Department of Cardiology, Heart Center (K.N.), Tampere University Hospital, Finland.
- 700 1_
- $a Pilbrow, Anna P $u The Christchurch Heart Institute, University of Otago Christchurch, New Zealand (A.P.P., A.M.R., V.A.C.).
- 700 1_
- $a Ploski, Rafal $u Department of Medical Genetics (R. Ploski), Medical University of Warsaw, Poland.
- 700 1_
- $a Sun, Yan V $u Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA (Y.V.S.). Department of Biomedical Informatics (Y.V.S.), Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA.
- 700 1_
- $a Tanck, Michael W T $u Amsterdam UMC, University of Amsterdam, Clinical Epidemiology and Biostatistics, The Netherlands (M.W.T.T.).
- 700 1_
- $a Tang, W H Wilson $u Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, OH (W.H.W.T., S.L.H.). Department of Cardiovascular Medicine, Heart and Vascular Institute, and Centre for Clinical Genomics, Cleveland Clinic, OH (W.H.W.T.).
- 700 1_
- $a Trompet, Stella $u Section of Gerontology and Geriatrics, Department of Internal Medicine (S.T.), Leiden University Medical Centre, the Netherlands. Department of Cardiology (S.T., J.W.J.), Leiden University Medical Centre, the Netherlands.
- 700 1_
- $a van der Laan, Sander W $u Division Laboratories, Pharmacy, and Biomedical Genetics, Laboratory of Clinical Chemistry and Hematology (S.W.v.d.L.), UMC Utrecht, Utrecht University, the Netherlands.
- 700 1_
- $a Van Setten, Jessica $u Division Heart and Lungs, Department of Cardiology, UMC Utrecht, University of Utrecht, the Netherlands (J.V.S.).
- 700 1_
- $a Vilmundarson, Ragnar O $u Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, ON, Canada (R.O.V., R.M., A.F.R.S.). Department of Biochemistry, Microbiology and Immunology (R.O.V., A.F.R.S.), University of Ottawa, ON, Canada.
- 700 1_
- $a Viviani Anselmi, Chiara $u Department of Cardiovascular Medicine, Humanitas Clinical and Research Centre, Milan, Italy (C.V.A., G.C.).
- 700 1_
- $a Vlachopoulou, Efthymia $u Transplantation Laboratory (E.V., M.-L.L.), Helsinki University Hospital and University of Helsinki, Finland.
- 700 1_
- $a Al Ali, Lawien $u University Medical Centre, University of Groningen, the Netherlands (L.A.A., P.V.d.H.).
- 700 1_
- $a Boerwinkle, Eric $u University of Texas School of Public Health, Houston(E.B.).
- 700 1_
- $a Briguori, Carlo $u Clinica Mediterranea, Naples, Italy (C.B.).
- 700 1_
- $a Carlquist, John F $u Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (R.O.M., J.F.C., J.B.M., J.L.A., B.D.H). Cardiology Division, Department of Internal Medicine (J.F.C., J.B.M., J.L.A.), University of Utah, Salt Lake City.
- 700 1_
- $a Carruthers, Kathryn F $u QMRI, Cardiovascular Sciences, University of Edinburgh, United Kingdom (K.F.C.).
- 700 1_
- $a Casu, Gavino $u Department of Cardiovascular Medicine, Humanitas Clinical and Research Centre, Milan, Italy (C.V.A., G.C.). ATS Sardegna, ASSL Nuoro-Ospedale San Francesco, Nuoro, Italy (G.C.). Department of Biomedical Sciences, Humanitas University, Milan, Italy (G.C.).
- 700 1_
- $a Deanfield, John $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom. Bart's Heart Centre, St Bartholomew's Hospital, London (R.S.P., J.D., A. Timmis).
- 700 1_
- $a Deloukas, Panos $u William Harvey Research Institute, Barts and the London Medical School (P.D), Queen Mary University of London, United Kingdom. Centre for Genomic Health (P.D.), Queen Mary University of London, United Kingdom.
- 700 1_
- $a Dudbridge, Frank $u Department of Health Sciences, University of Leicester, United Kingdom (F.D.).
- 700 1_
- $a Engstrøm, Thomas $u Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet (C.G., T.E., R.J.). Department of Cardiology, University of Lund, Sweden (T.E.).
- 700 1_
- $a Fitzpatrick, Natalie $u Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.
- 700 1_
- $a Fox, Kim $u National Heart and Lung Institute, Imperial College and Institute of Cardiovascular Medicine and Science, Royal Brompton Hospital, London, United Kingdom (K.F.).
- 700 1_
- $a Gigante, Bruna $u Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden (K.L., B.G., U.d.F.).
- 700 1_
- $a James, Stefan $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Cardiology, Department of Medical Sciences (A. Åkerblom, C.H., D. Lindholm, S.J., B.L., L.W.), Uppsala University, Sweden.
- 700 1_
- $a Lokki, Marja-Liisa $u Transplantation Laboratory (E.V., M.-L.L.), Helsinki University Hospital and University of Helsinki, Finland.
- 700 1_
- $a Lotufo, Paulo A $u Centro de Pesquisa Clinica, Hospital Universitario, Universidade de Sao Paulo, São Paulo, Brazil (P.A. Lotufo, ).
- 700 1_
- $a Marziliano, Nicola $u ATS Sardegna, ASL 3 Nuoro, Nuoro, Italy (N. Marziliano).
- 700 1_
- $a Mordi, Ify R $u Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Scotland, United Kingdom (D. Levin, I.R.M., C.C.L.).
- 700 1_
- $a Muhlestein, Joseph B $u Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (R.O.M., J.F.C., J.B.M., J.L.A., B.D.H). Cardiology Division, Department of Internal Medicine (J.F.C., J.B.M., J.L.A.), University of Utah, Salt Lake City.
- 700 1_
- $a Newton-Cheh, Christopher $u Cardiovascular Research Center, Center for Human Genetic Research, Massachusetts General Hospital, Boston (C.N.-C.). Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (C.N.-C.).
- 700 1_
- $a Pitha, Jan $u Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic (J.A.H., J.P.).
- 700 1_
- $a Saely, Christoph H $u Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria (A. Leiherer, C.H.S., H.D.). Private University of the Principality of Liechtenstein, Triesen (A. Leiherer, C.H.S., H.D.). Department of Medicine and Cardiology, Academic Teaching Hospital Feldkirch, Austria (C.H.S.).
- 700 1_
- $a Samman-Tahhan, Ayman $u Division of Cardiology, Department of Medicine (A.S.-T., P.B.S., A.A.Q.), Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA.
- 700 1_
- $a Sandesara, Pratik B $u Division of Cardiology, Department of Medicine (A.S.-T., P.B.S., A.A.Q.), Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA.
- 700 1_
- $a Teren, Andrej $u LIFE Research Centre for Civilization Diseases (M.S., A. Teren, R.B., J.T.), University of Leipzig, Germany. Heart Centre Leipzig, Germany (A. Teren).
- 700 1_
- $a Timmis, Adam $u Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom. Bart's Heart Centre, St Bartholomew's Hospital, London (R.S.P., J.D., A. Timmis).
- 700 1_
- $a Van de Werf, Frans $u Department of Cardiovascular Sciences (F.V.d.W.), Katholieke Universiteit Leuven, Belgium.
- 700 1_
- $a Wauters, Els $u Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospitals KU Leuven, Belgium (E.W.).
- 700 1_
- $a Wilde, Arthur A M $u Amsterdam UMC, University of Amsterdam, Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, AMC Heart Center, the Netherlands (C.G., A.A.M.W., C.R.B.). Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Saudi Arabia (A.A.M.W.).
- 700 1_
- $a Ford, Ian $u Robertson Centre for Biostatistics, University of Glasgow, United Kingdom (I.F.).
- 700 1_
- $a Stott, David J $u Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (D.J.S., N.S.).
- 700 1_
- $a Algra, Ale $u Department of Neurology and Neurosurgery, Brain Centre Rudolf Magnus and Julius Centre for Health Sciences and Primary Care (A. Algra), UMC Utrecht, Utrecht University, the Netherlands.
- 700 1_
- $a Andreassi, Maria G $u CNR Institute of Clinical Physiology, Pisa (M.G.A, C.C).
- 700 1_
- $a Ardissino, Diego $u Cardiology Department, Parma University Hospital, Italy (D.A.).
- 700 1_
- $a Arsenault, Benoit J $u Centre de recherche de l'Institut Universitaire de cardiologie et de pneumologie de Québec, Canada (B.J.A.). Department of Medicine, Faculty of Medicine, Université Laval, QC, Canada (B.J.A.).
- 700 1_
- $a Ballantyne, Christie M $u Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX (S.S.V., C.M.B.).
- 700 1_
- $a Bergmeijer, Thomas O $u St Antonius Hospital, Department Cardiology, Nieuwegein, the Netherlands (T.O.B., B.K.M., J.M.t.B.).
- 700 1_
- $a Bezzina, Connie R $u Amsterdam UMC, University of Amsterdam, Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, AMC Heart Center, the Netherlands (C.G., A.A.M.W., C.R.B.).
- 700 1_
- $a Body, Simon C $u Harvard Medical School, Boston, MA (J.D.M., M.H., S.C.B). Department of Anesthesia, Critical Care & Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA (S.B.).
- 700 1_
- $a Boersma, Eric H $u Department of Cardiology, Erasmus MC, Thoraxcenter (E.H.B., J.J.B.). Cardiovascular Research School, Erasmus Medical Center (COEUR), Rotterdam, the Netherlands(E.H.B.).
- 700 1_
- $a Bogaty, Peter $u Laval University, Institute universitaire de cardiologie et de pneumologie de Québec, Canada (P.B.).
- 700 1_
- $a Bots, Michiel L $u Julius Center for Health Sciences and Primary Care (M.B., D.E.G., Y.v.d.G.), UMC Utrecht, Utrecht University, the Netherlands.
- 700 1_
- $a Brenner, Hermann $u Network Aging Research (NAR), University of Heidelberg (H.B.).
- 700 1_
- $a Brugts, Jasper J $u Department of Cardiology, Erasmus MC, Thoraxcenter (E.H.B., J.J.B.).
- 700 1_
- $a Burkhardt, Ralph $u LIFE Research Centre for Civilization Diseases (M.S., A. Teren, R.B., J.T.), University of Leipzig, Germany. Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Germany (R.B.).
- 700 1_
- $a Carpeggiani, Clara $u CNR Institute of Clinical Physiology, Pisa (M.G.A, C.C).
- 700 1_
- $a Condorelli, Gianluigi $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom.
- 700 1_
- $a Cooper-DeHoff, Rhonda M $u Department of Pharmacotherapy and Translational Research, Centre for Pharmacogenomics (Y.G., R.M.C.-D., J.A.J.), University of Florida, Gainesville. Division of Cardiovascular Medicine, College of Medicine (R.M.C.-D., J.A.J., C.J.P.), University of Florida, Gainesville.
- 700 1_
- $a Cresci, Sharon $u Statistical Genomics Division, Department of Genetics (P.A. Lenzini, S.C.), Washington University School of Medicine, Saint Louis, MO. Cardiovascular Division, Department of Medicine (S.C.), Washington University School of Medicine, Saint Louis, MO.
- 700 1_
- $a Danchin, Nicolas $u Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Cardiology, Hôpital Européen Georges Pompidou & FACT (French Alliance For Cardiovascular Trials), Université Paris Descartes, France (N.D.). Université Paris-Descartes, France (N.D.).
- 700 1_
- $a de Faire, Ulf $u Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden (K.L., B.G., U.d.F.).
- 700 1_
- $a Doughty, Robert N $u Heart Health Research Group, University of Auckland, New Zealand (R.N.D.).
- 700 1_
- $a Drexel, Heinz $u Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria (A. Leiherer, C.H.S., H.D.). Private University of the Principality of Liechtenstein, Triesen (A. Leiherer, C.H.S., H.D.). Drexel University College of Medicine, Philadelphia PA (H.D.).
- 700 1_
- $a Engert, James C $u Research Institute of the McGill University Health Centre, Montreal, QC, Canada (J.C.E.). Preventive and Genomic Cardiology, McGill University Health Centre, Montreal, QC, Canada (L.D., J.C.E., G.T.). Division of Cardiology, Department of Medicine, Royal Victoria Hospital, McGill Univ Health Centre, Montreal, QC, Canada (J.C.E., G.T.).
- 700 1_
- $a Fox, Keith A A $u The University of Edinburgh, United Kingdom (K.A.A.F).
- 700 1_
- $a Girelli, Domenico $u Department of Medicine, University of Verona, Italy (N.M., D.G., O.O.).
- 700 1_
- $a Grobbee, Diederick E $u Julius Center for Health Sciences and Primary Care (M.B., D.E.G., Y.v.d.G.), UMC Utrecht, Utrecht University, the Netherlands.
- 700 1_
- $a Hagström, Emil $u Department of Cardiology, Uppsala Clinical Research Centre, Uppsala University, Sweden (E.H.).
- 700 1_
- $a Hazen, Stanley L $u Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, OH (W.H.W.T., S.L.H.). Department of Cardiovascular Medicine, Centre for Microbiome and Human Health, Heart and Vascular Institute, Cleveland Clinic, OH (S.L.H.).
- 700 1_
- $a Held, Claes $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Cardiology, Department of Medical Sciences (A. Åkerblom, C.H., D. Lindholm, S.J., B.L., L.W.), Uppsala University, Sweden.
- 700 1_
- $a Hemingway, Harry $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom.
- 700 1_
- $a Hoefer, Imo E $u Department of Clinical Chemistry and Hematology (I.E.H.), UMC Utrecht, the Netherlands.
- 700 1_
- $a Hovingh, G Kees $u Department of Vascular Medicine, Academic Medical Centre, Amsterdam (G.K.H.).
- 700 1_
- $a Jabbari, Reza $u Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet (C.G., T.E., R.J.).
- 700 1_
- $a Johnson, Julie A $u Department of Pharmacotherapy and Translational Research, Centre for Pharmacogenomics (Y.G., R.M.C.-D., J.A.J.), University of Florida, Gainesville. Division of Cardiovascular Medicine, College of Medicine (R.M.C.-D., J.A.J., C.J.P.), University of Florida, Gainesville.
- 700 1_
- $a Jukema, J Wouter $u Department of Cardiology (S.T., J.W.J.), Leiden University Medical Centre, the Netherlands. Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden (J.W.J.). Interuniversity Cardiology Institute of the Netherlands, Utrecht (J.W.J.).
- 700 1_
- $a Kaczor, Marcin P $u Department of Internal Medicine, Jagiellonian University Medical College, Kraków, Poland (M.P.K., M.S., W.S).
- 700 1_
- $a Kähönen, Mika $u Department of Clinical Physiology (M. Kähönen), University of Tampere, Finland. Department of Clinical Physiology (M. Kähönen), Tampere University Hospital, Finland.
- 700 1_
- $a Kettner, Jiri $u Cardiology Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic (J.K.).
- 700 1_
- $a Kiliszek, Marek $u Department of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland (M. Kiliszek).
- 700 1_
- $a Klungel, Olaf H $u Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, the Netherlands (E.V.B., O.H.K., A.H.M.-v.d.Z.).
- 700 1_
- $a Lagerqvist, Bo $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Cardiology, Department of Medical Sciences (A. Åkerblom, C.H., D. Lindholm, S.J., B.L., L.W.), Uppsala University, Sweden.
- 700 1_
- $a Lambrechts, Diether $u Laboratory for Translational Genetics, Department of Human Genetics (B.B., D. Lambrechts), Katholieke Universiteit Leuven, Belgium.
- 700 1_
- $a Laurikka, Jari O $u Department of Cardio-Thoracic Surgery, Finnish Cardiovascular Research Center, Faculty of Medicine & Life Sciences (J.O.L.), University of Tampere, Finland. Department of Cardio-Thoracic Surgery, Heart Centre (J.O.L.), Tampere University Hospital, Finland.
- 700 1_
- $a Lehtimäki, Terho $u Department of Clinical Chemistry (L.-P.L., T.L.), University of Tampere, Finland. Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., T.L.).
- 700 1_
- $a Lindholm, Daniel $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Cardiology, Department of Medical Sciences (A. Åkerblom, C.H., D. Lindholm, S.J., B.L., L.W.), Uppsala University, Sweden.
- 700 1_
- $a Mahmoodi, B K $u St Antonius Hospital, Department Cardiology, Nieuwegein, the Netherlands (T.O.B., B.K.M., J.M.t.B.).
- 700 1_
- $a Maitland-van der Zee, Anke H $u Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, the Netherlands (E.V.B., O.H.K., A.H.M.-v.d.Z.). Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam (A.H.M.-v.d.Z.).
- 700 1_
- $a McPherson, Ruth $u Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, ON, Canada (R.O.V., R.M., A.F.R.S.). Departments of Medicine and Biochemistry, Microbiology and Immunology(R.M.), University of Ottawa, ON, Canada.
- 700 1_
- $a Melander, Olle $u Department of Clinical Sciences, Lund University, Malmö, Sweden (P.A., O.M.). Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden (O.M.).
- 700 1_
- $a Metspalu, Andres $u Estonian Genome Centre, Department of Biotechnology, Institute of Genomics, Institute of Molecular and Cell Biology, University of Tartu, Estonia (M.A., A.M.).
- 700 1_
- $a Niemcunowicz-Janica, Anna $u Department of Forensic Medicine; Medical University of Bialystok (A.N.-J.).
- 700 1_
- $a Olivieri, Oliviero $u Department of Medicine, University of Verona, Italy (N.M., D.G., O.O.).
- 700 1_
- $a Opolski, Grzegorz $u first Chair and Department of Cardiology (G.O.), Medical University of Warsaw, Poland.
- 700 1_
- $a Palmer, Colin N $u Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, Dundee (C.N.P.).
- 700 1_
- $a Pasterkamp, Gerard $u Department of Clinical Chemistry (G.P.), UMC Utrecht, the Netherlands.
- 700 1_
- $a Pepine, Carl J $u Division of Cardiovascular Medicine, College of Medicine (R.M.C.-D., J.A.J., C.J.P.), University of Florida, Gainesville.
- 700 1_
- $a Pereira, Alexandre C $u Heart Institute, University of Sao Paulo, Brazil (N.E.D., A.C.P.).
- 700 1_
- $a Pilote, Louise $u Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada (H.B., L.D., L.P., G.T., J.M.B.). Department of Medicine, McGill University Health Centre, Montreal, QC, Canada (L.P., J.M.B.).
- 700 1_
- $a Quyyumi, Arshed A $u Division of Cardiology, Department of Medicine (A.S.-T., P.B.S., A.A.Q.), Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA.
- 700 1_
- $a Richards, A Mark $u The Christchurch Heart Institute, University of Otago Christchurch, New Zealand (A.P.P., A.M.R., V.A.C.). Cardiovascular Research Institute, National University of Singapore (A.M.R.).
- 700 1_
- $a Sanak, Marek $u Department of Internal Medicine, Jagiellonian University Medical College, Kraków, Poland (M.P.K., M.S., W.S).
- 700 1_
- $a Siegbahn, Agneta $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Clinical Chemistry, Department of Medical Sciences (A. Siegbahn), Uppsala University, Sweden.
- 700 1_
- $a Simon, Tabassome $u Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Clinical Pharmacology, Platform of Clinical Research of East Paris (URCEST-CRCEST-CRB HUEP-UPMC), FACT (French Alliance for Cardiovascular Trials), Sorbonne Université (T.S.). Paris-Sorbonne University, UPMC-Site St Antoine, France (T.S.).
- 700 1_
- $a Sinisalo, Juha $u Heart and Lung Centre (J.S.), Helsinki University Hospital and University of Helsinki, Finland.
- 700 1_
- $a Smith, J Gustav $u Department of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital (J.G.S.). Wallenberg Centre for Molecular Medicine, Lund University Diabetes Centre, Lund University, Sweden (J.G.S.). Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (J.G.S.).
- 700 1_
- $a Spertus, John A $u Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City (J.A.S.). Saint Luke's Mid America Heart Insti Kansas City, MO (J.A.S.).
- 700 1_
- $a Stender, Steen $u Department of Clinical Biochemistry, Copenhagen University Hospital, Gentofte (S.S.).
- 700 1_
- $a Stewart, Alexandre F R $u Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, ON, Canada (R.O.V., R.M., A.F.R.S.). Department of Biochemistry, Microbiology and Immunology (R.O.V., A.F.R.S.), University of Ottawa, ON, Canada.
- 700 1_
- $a Szczeklik, Wojciech $u Department of Internal Medicine, Jagiellonian University Medical College, Kraków, Poland (M.P.K., M.S., W.S).
- 700 1_
- $a Szpakowicz, Anna $u Department of Cardiology (K.A.K., A. Szpakowicz), Medical University of Bialystok, Poland.
- 700 1_
- $a Tardif, Jean-Claude $u Montreal Heart Institute, OC, Canada (M.-P.D., J.-C.T.). Faculty of Medicine, Université de Montréal, QC, Canada (M.-P.D., J.-C.T.).
- 700 1_
- $a Ten Berg, Jurriën M $u St Antonius Hospital, Department Cardiology, Nieuwegein, the Netherlands (T.O.B., B.K.M., J.M.t.B.).
- 700 1_
- $a Tfelt-Hansen, Jacob $u Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet (J.T.-H.). Department of Forensic Medicine, Faculty of Medical Sciences, University of Copenhagen, Denmark (J.T.-Hansen).
- 700 1_
- $a Thanassoulis, George $u Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada (H.B., L.D., L.P., G.T., J.M.B.). Preventive and Genomic Cardiology, McGill University Health Centre, Montreal, QC, Canada (L.D., J.C.E., G.T.). Division of Cardiology, Department of Medicine, Royal Victoria Hospital, McGill Univ Health Centre, Montreal, QC, Canada (J.C.E., G.T.).
- 700 1_
- $a Thiery, Joachim $u LIFE Research Centre for Civilization Diseases (M.S., A. Teren, R.B., J.T.), University of Leipzig, Germany. Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital, Leipzig, Germany (J.T.).
- 700 1_
- $a Torp-Pedersen, Christian $u Unit of Epidemiology and Biostatistics, Department of Health Science and Technology, Aalborg University Hospital, Denmark (C.T.-Pedersen).
- 700 1_
- $a van der Graaf, Yolanda $u Julius Center for Health Sciences and Primary Care (M.B., D.E.G., Y.v.d.G.), UMC Utrecht, Utrecht University, the Netherlands.
- 700 1_
- $a Visseren, Frank L J $u Department of Vascular Medicine (F.L.J.V), UMC Utrecht, Utrecht University, the Netherlands.
- 700 1_
- $a Waltenberger, Johannes $u Department of Cardiovascular Medicine, University of Münster, Germany (J.W.).
- 700 1_
- $a Weeke, Peter E $u Department of Cardiology, Herlev and Gentofte Hospital, Hellerup, Denmark (P.E.W.).
- 700 1_
- $a Van der Harst, Pim $u University Medical Centre, University of Groningen, the Netherlands (L.A.A., P.V.d.H.).
- 700 1_
- $a Lang, Chim C $u Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Scotland, United Kingdom (D. Levin, I.R.M., C.C.L.).
- 700 1_
- $a Sattar, Naveed $u Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (D.J.S., N.S.).
- 700 1_
- $a Cameron, Vicky A $u The Christchurch Heart Institute, University of Otago Christchurch, New Zealand (A.P.P., A.M.R., V.A.C.).
- 700 1_
- $a Anderson, Jeffrey L $u Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (R.O.M., J.F.C., J.B.M., J.L.A., B.D.H). Cardiology Division, Department of Internal Medicine (J.F.C., J.B.M., J.L.A.), University of Utah, Salt Lake City.
- 700 1_
- $a Brophy, James M $u Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada (H.B., L.D., L.P., G.T., J.M.B.). Department of Medicine, McGill University Health Centre, Montreal, QC, Canada (L.P., J.M.B.).
- 700 1_
- $a Pare, Guillaume $u Department of Pathology and Molecular Medicine, McMaster University (G.P.). Population Health Research Institute, Hamilton, ON, Canada (G.P.).
- 700 1_
- $a Horne, Benjamin D $u Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (R.O.M., J.F.C., J.B.M., J.L.A., B.D.H). Department of Biomedical Informatics (B.D.H.), University of Utah, Salt Lake City.
- 700 1_
- $a März, Winfried $u Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (G.D., M. Kleber, W.M.). Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany (W.M.). Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria (W.M.).
- 700 1_
- $a Wallentin, Lars $u Uppsala Clinical Research Center, Sweden (A. Åkerblom, N.E., S.J., C.H., B.L., D. Lindholm, A. Siegbahn, L.W.). Division of Cardiology, Department of Medical Sciences (A. Åkerblom, C.H., D. Lindholm, S.J., B.L., L.W.), Uppsala University, Sweden.
- 700 1_
- $a Samani, Nilesh J $u Department of Cardiovascular Sciences, BHF Cardiovascular Research Centre, University of Leicester, United Kingdom (P.S.B., C.P.N., N.J.S.). NIHR Leicester Biomedical Research Centre, Glenfield Hospital, United Kingdom (P.S.B., C.P.N., N.J.S.).
- 700 1_
- $a Hingorani, Aroon D $u Institute of Cardiovascular Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A), Faculty of Population Health Science, University College London, United Kingdom.
- 700 1_
- $a Asselbergs, Folkert W $u Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom. Division of Heart and Lungs, Department of Cardiology (V.T., A.F.S.,D.K.,F.W.A.), UMC Utrecht, the Netherlands. Durrer Centre of Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht (F.W.A.).
- 773 0_
- $w MED00205617 $t Circulation. Genomic and precision medicine $x 2574-8300 $g Roč. 12, č. 4 (2019), s. e002470
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/30896328 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20201125 $b ABA008
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