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Noncoding RNAs in Parasite-Vector-Host Interactions
C. Bensaoud, M. Hackenberg, M. Kotsyfakis,
Language English Country Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Homeostasis physiology MeSH
- Disease Vectors * MeSH
- Host-Parasite Interactions genetics immunology MeSH
- Humans MeSH
- RNA, Untranslated genetics immunology MeSH
- Vertebrates immunology parasitology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Systems biology approaches, especially in the big data era, have revolutionized modern parasitology. Of the many different molecules participating in parasite-host interactions, noncoding RNAs (ncRNAs) are now known to be (i) transmitted by the vector to possibly modulate vertebrate host responses and favor vector survival and (ii) regulated in the host by parasites to favor parasite survival. Here we provide an overview of the involvement of ncRNAs in the parasite-vector-host triad and their effect on host homeostasis based on recent advances and accumulating knowledge about the role of endogenous vertebrate noncoding RNAs in vertebrate host physiology.
References provided by Crossref.org
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