-
Je něco špatně v tomto záznamu ?
Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach
G. Di Credico, V. Edefonti, J. Polesel, F. Pauli, N. Torelli, D. Serraino, E. Negri, D. Luce, I. Stucker, K. Matsuo, P. Brennan, M. Vilensky, L. Fernandez, MP. Curado, A. Menezes, AW. Daudt, R. Koifman, V. Wunsch-Filho, I. Holcatova, W. Ahrens,...
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, práce podpořená grantem
Grantová podpora
P01 CA068384
NCI NIH HHS - United States
R01 DA011386
NIDA NIH HHS - United States
R01 CA030022
NCI NIH HHS - United States
R01 ES011740
NIEHS NIH HHS - United States
R03 TW001500
FIC NIH HHS - United States
R01 DE016631
NIDCR NIH HHS - United States
R01 CA100679
NCI NIH HHS - United States
R03 CA113157
NCI NIH HHS - United States
R01 CA100264
NCI NIH HHS - United States
P30 ES010126
NIEHS NIH HHS - United States
R01 DA011979
NIDA NIH HHS - United States
R13 CA210555
NCI NIH HHS - United States
R01 DE013158
NIDCR NIH HHS - United States
R01 CA078609
NCI NIH HHS - United States
K07 CA104231
NCI NIH HHS - United States
T32 CA009142
NCI NIH HHS - United States
U01 CA096134
NCI NIH HHS - United States
R01 CA090731
NCI NIH HHS - United States
R03 CA077954
NCI NIH HHS - United States
R21 ES011667
NIEHS NIH HHS - United States
R03 DE016611
NIDCR NIH HHS - United States
R01 CA048996
NCI NIH HHS - United States
P50 CA090388
NCI NIH HHS - United States
R01 DE013110
NIDCR NIH HHS - United States
- MeSH
- dospělí MeSH
- kouření cigaret škodlivé účinky MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory hlavy a krku etiologie patologie MeSH
- rizikové faktory MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- studie případů a kontrol MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
OBJECTIVES: This study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures. MATERIALS AND METHODS: We pooled individual-level data from 33 case-control studies (18,260 HNC cases and 29,844 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. In bivariate regression spline models, exposures to cigarette smoking intensity and duration (compared with never smokers) were modeled as a linear piecewise function within a logistic regression also including potential confounders. We jointly estimated the optimal knot locations and regression parameters within the Bayesian framework. RESULTS: For oral-cavity/pharyngeal (OCP) cancers, an odds ratio (OR) >5 was reached after 30 years in current smokers of ∼20 or more cigarettes/day. Patterns of OCP cancer risk in current smokers differed across strata of alcohol intensity. For laryngeal cancer, ORs >20 were found for current smokers of ≥20 cigarettes/day for ≥30 years. In former smokers who quit ≥10 years ago, the ORs were approximately halved for OCP cancers, and ∼1/3 for laryngeal cancer, as compared to the same levels of intensity and duration in current smokers. CONCLUSION: Referring to bivariate spline models, this study better quantified the joint effect of intensity and duration of cigarette smoking on HNC risk, further stressing the need of smoking cessation policies.
Aichi Cancer Center Research Institute Nagoya Japan
Boston University School of Public Health Boston MA USA
Brown University Providence RI USA
Cancer Epidemiology Unit Centro di Riferimento Oncologico di Aviano IRCCS Aviano Italy
Cancer Registry of Norway Oslo Norway
Cancer Research Centre Moscow Russia
College of Public Health University of Iowa Iowa City IA USA
Department of Biomedical and Clinical Sciences Università degli Studi di Milano Milano Italy
Department of Economics Business Mathematics and Statistics University of Trieste Trieste Italy
Department of Epidemiology Brown University School of Public Health Providence RI USA
Department of Medical Sciences University of Turin Turin Italy
Department of Oncology Istituto di Ricerche Farmacologiche Mario Negri IRCCS Milan Italy
Department of Statistics Padua University Padua Italy
Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA
Division of Epidemiology New York University School Of Medicine New York NY USA
Division of Preventive Oncology German Cancer Research Center Heidelberg Germany
Epidemiology CIPE ACCAMARGO Sao Paulo Brazil
Escola Nacional de Saude Publica Fundacao Oswaldo Cruz Rio de Janeiro Brazil
German Cancer Consortium Heidelberg Germany
Hospital Moinhos de Vento Porto Alegre Brazil
Institut Catala Oncologia Barcelona Spain
Institute of Occupational Medicine Lodz Poland
Institute of Oncology and Radiobiology Havana Cuba
Institute of Oncology Angel H Roffo University of Buenos Aires Argentina
Institute of Population Health Sciences National Health Research Institutes Taiwan
International Agency for Research on Cancer Lyon France
Istituto di Clinica Otorinolaringoiatrica Università Cattolica del Sacro Cuore Roma Italy
Johns Hopkins Bloomberg School of Public Health Baltimore MD USA
Leibniz Institute for Prevention Research and Epidemiology BIPS Bremen Germany
Medical Informatics Center Peking University China
National Institute of Environmental Health to National Public Health Institute Budapest Hungary
National Institute of Public Health Bucharest Romania
New York Eye and Ear Infirmary New York NY USA
Penn State College of Medicine Hershey PA USA
Regional Authority of Public Health in Banska Bystrica Slovakia
Roswell Park Cancer Institute Buffalo NY USA
School of Medicine Dentistry and Nursing University of Glasgow Glasgow UK
Sezione di Igiene Istituto di Sanità Pubblica Università Cattolica del Sacro Cuore Roma Italy
The Tisch Cancer Institute Icahn School of Medicine at Mount Sinai New York NY USA
Thoracic Head and Neck Medical Oncology The University of Texas MD Anderson Cancer Center TX USA
Trinity College School of Dental Science Dublin Ireland
UCLA School of Public Health Los Angeles CA USA
Universidade Federal de Pelotas Pelotas Brazil
Université de Rennes INSERM EHESP Irset UMR_S 1085 Pointe à Pitre France
University of Bremen Faculty of Mathematics and Computer Science Bremen Germany
University of Heidelberg Germany
University of Hong Kong Hong Kong China
University of North Carolina School of Public Health Chapel Hill NC USA
University of São Paulo School of Medicine São Paulo Brazil
University of São Paulo School of Public Health São Paulo Brazil
UT M D Anderson Cancer Center Houston TX USA
Washington State University College of Pharmacy and Pharmaceutical Sciences Spokane WA USA
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc20023869
- 003
- CZ-PrNML
- 005
- 20201214131515.0
- 007
- ta
- 008
- 201125s2019 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.oraloncology.2019.05.006 $2 doi
- 035 __
- $a (PubMed)31178212
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a Di Credico, Gioia $u Department of Statistics, Padua University, Padua, Italy; Department of Economics, Business, Mathematics and Statistics, University of Trieste, Trieste, Italy.
- 245 10
- $a Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach / $c G. Di Credico, V. Edefonti, J. Polesel, F. Pauli, N. Torelli, D. Serraino, E. Negri, D. Luce, I. Stucker, K. Matsuo, P. Brennan, M. Vilensky, L. Fernandez, MP. Curado, A. Menezes, AW. Daudt, R. Koifman, V. Wunsch-Filho, I. Holcatova, W. Ahrens, P. Lagiou, L. Simonato, L. Richiardi, C. Healy, K. Kjaerheim, DI. Conway, TV. Macfarlane, P. Thomson, A. Agudo, A. Znaor, LF. Boaventura Rios, TN. Toporcov, S. Franceschi, R. Herrero, J. Muscat, AF. Olshan, JP. Zevallos, C. La Vecchia, DM. Winn, EM. Sturgis, G. Li, E. Fabianova, J. Lissowska, D. Mates, P. Rudnai, O. Shangina, B. Swiatkowska, K. Moysich, ZF. Zhang, H. Morgenstern, F. Levi, E. Smith, P. Lazarus, C. Bosetti, W. Garavello, K. Kelsey, M. McClean, H. Ramroth, C. Chen, SM. Schwartz, TL. Vaughan, T. Zheng, G. Menvielle, S. Boccia, G. Cadoni, RB. Hayes, M. Purdue, M. Gillison, S. Schantz, GP. Yu, H. Brenner, G. D'Souza, ND. Gross, SC. Chuang, P. Boffetta, M. Hashibe, YA. Lee, L. Dal Maso,
- 520 9_
- $a OBJECTIVES: This study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures. MATERIALS AND METHODS: We pooled individual-level data from 33 case-control studies (18,260 HNC cases and 29,844 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. In bivariate regression spline models, exposures to cigarette smoking intensity and duration (compared with never smokers) were modeled as a linear piecewise function within a logistic regression also including potential confounders. We jointly estimated the optimal knot locations and regression parameters within the Bayesian framework. RESULTS: For oral-cavity/pharyngeal (OCP) cancers, an odds ratio (OR) >5 was reached after 30 years in current smokers of ∼20 or more cigarettes/day. Patterns of OCP cancer risk in current smokers differed across strata of alcohol intensity. For laryngeal cancer, ORs >20 were found for current smokers of ≥20 cigarettes/day for ≥30 years. In former smokers who quit ≥10 years ago, the ORs were approximately halved for OCP cancers, and ∼1/3 for laryngeal cancer, as compared to the same levels of intensity and duration in current smokers. CONCLUSION: Referring to bivariate spline models, this study better quantified the joint effect of intensity and duration of cigarette smoking on HNC risk, further stressing the need of smoking cessation policies.
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 _2
- $a studie případů a kontrol $7 D016022
- 650 _2
- $a kouření cigaret $x škodlivé účinky $7 D000073865
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a nádory hlavy a krku $x etiologie $x patologie $7 D006258
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a rizikové faktory $7 D012307
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a Research Support, N.I.H., Extramural $7 D052061
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Edefonti, Valeria $u Branch of Medical Statistics, Biometry and Epidemiology "G. A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milano, Italy. Electronic address: valeria.edefonti@unimi.it.
- 700 1_
- $a Polesel, Jerry $u Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy.
- 700 1_
- $a Pauli, Francesco $u Department of Economics, Business, Mathematics and Statistics, University of Trieste, Trieste, Italy.
- 700 1_
- $a Torelli, Nicola $u Department of Economics, Business, Mathematics and Statistics, University of Trieste, Trieste, Italy.
- 700 1_
- $a Serraino, Diego $u Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy.
- 700 1_
- $a Negri, Eva $u Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milano, Italy.
- 700 1_
- $a Luce, Daniele $u Université de Rennes, INSERM, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail), UMR_S 1085, Pointe-à-Pitre, France.
- 700 1_
- $a Stucker, Isabelle $u Inserm, Center for Research in Epidemiology and Population Health (CESP), Cancer and Environment team, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
- 700 1_
- $a Matsuo, Keitaro $u Aichi Cancer Center Research Institute, Nagoya, Japan.
- 700 1_
- $a Brennan, Paul $u International Agency for Research on Cancer, Lyon, France.
- 700 1_
- $a Vilensky, Marta $u Institute of Oncology Angel H. Roffo, University of Buenos Aires, Argentina.
- 700 1_
- $a Fernandez, Leticia $u Institute of Oncology and Radiobiology, Havana, Cuba.
- 700 1_
- $a Curado, Maria Paula $u Epidemiology, CIPE/ACCAMARGO, Sao Paulo, Brazil.
- 700 1_
- $a Menezes, Ana $u Universidade Federal de Pelotas, Pelotas, Brazil.
- 700 1_
- $a Daudt, Alexander W $u Hospital Moinhos de Vento, Porto Alegre, Brazil.
- 700 1_
- $a Koifman, Rosalina $u Escola Nacional de Saude Publica, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil.
- 700 1_
- $a Wunsch-Filho, Victor $u University of São Paulo School of Public Health, São Paulo, Brazil.
- 700 1_
- $a Holcatova, Ivana $u Institute of Hygiene & Epidemiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
- 700 1_
- $a Ahrens, Wolfgang $u Leibniz Institute for Prevention Research and Epidemiology, BIPS, Bremen, Germany; University of Bremen, Faculty of Mathematics and Computer Science, Bremen, Germany.
- 700 1_
- $a Lagiou, Pagona $u Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
- 700 1_
- $a Simonato, Lorenzo $u Department of Cardiovascular and Thoracic Sciences and Public Health, University of Padova, Padova, Italy.
- 700 1_
- $a Richiardi, Lorenzo $u Department of Medical Sciences, University of Turin, Turin, Italy.
- 700 1_
- $a Healy, Claire $u Trinity College School of Dental Science, Dublin, Ireland.
- 700 1_
- $a Kjaerheim, Kristina $u Cancer Registry of Norway, Oslo, Norway.
- 700 1_
- $a Conway, David I $u School of Medicine, Dentistry, and Nursing, University of Glasgow, Glasgow, UK.
- 700 1_
- $a Macfarlane, Tatiana V $u School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK and School of Medicine, University of Dundee, Dundee, UK.
- 700 1_
- $a Thomson, Peter $u University of Hong Kong, Hong Kong, China.
- 700 1_
- $a Agudo, Antonio $u Institut Catala Oncologia, Barcelona, Spain.
- 700 1_
- $a Znaor, Ariana $u International Agency for Research on Cancer, Lyon, France.
- 700 1_
- $a Boaventura Rios, Leonardo F $u University of São Paulo School of Medicine, São Paulo, Brazil.
- 700 1_
- $a Toporcov, Tatiana N $u University of São Paulo School of Public Health, São Paulo, Brazil.
- 700 1_
- $a Franceschi, Silvia $u Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy.
- 700 1_
- $a Herrero, Rolando $u International Agency for Research on Cancer, Lyon, France.
- 700 1_
- $a Muscat, Joshua $u Penn State College of Medicine, Hershey, PA, USA.
- 700 1_
- $a Olshan, Andrew F $u University of North Carolina School of Public Health, Chapel Hill, NC, USA.
- 700 1_
- $a Zevallos, Jose P $u Division of Head and Neck Surgical Oncology in the Department of Otolaryngology/Head and Neck Surgery at Washington University School of Medicine, USA.
- 700 1_
- $a La Vecchia, Carlo $u Branch of Medical Statistics, Biometry and Epidemiology "G. A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milano, Italy.
- 700 1_
- $a Winn, Deborah M $u Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
- 700 1_
- $a Sturgis, Erich M $u UT - M.D. Anderson Cancer Center, Houston, TX, USA.
- 700 1_
- $a Li, Guojun $u UT - M.D. Anderson Cancer Center, Houston, TX, USA.
- 700 1_
- $a Fabianova, Eleonora $u Regional Authority of Public Health in Banska Bystrica, Slovakia.
- 700 1_
- $a Lissowska, Jolanda $u The M. Skasodowska-Curie Memorial Cancer Center and Institute of Oncology, Dept. of Cancer Epidemiology and Prevention, Warsaw, Poland.
- 700 1_
- $a Mates, Dana $u National Institute of Public Health, Bucharest, Romania.
- 700 1_
- $a Rudnai, Peter $u National Institute of Environmental Health to National Public Health Institute, Budapest, Hungary.
- 700 1_
- $a Shangina, Oxana $u Cancer Research Centre, Moscow, Russia.
- 700 1_
- $a Swiatkowska, Beata $u Institute of Occupational Medicine, Lodz, Poland.
- 700 1_
- $a Moysich, Kirsten $u Roswell Park Cancer Institute, Buffalo, NY, USA.
- 700 1_
- $a Zhang, Zuo-Feng $u UCLA School of Public Health, Los Angeles, CA, USA.
- 700 1_
- $a Morgenstern, Hal $u Departments of Epidemiology and Environmental Health Sciences, School of Public Health and Department of Urology, Medical School, University of Michigan, Ann Arbor, MI, USA.
- 700 1_
- $a Levi, Fabio $u Institut Universitaire de Medecine Sociale et Preventive (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
- 700 1_
- $a Smith, Elaine $u College of Public Health, University of Iowa, Iowa City, IA, USA.
- 700 1_
- $a Lazarus, Philip $u Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, WA, USA.
- 700 1_
- $a Bosetti, Cristina $u Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
- 700 1_
- $a Garavello, Werner $u Department of Otorhinolaryngology, School of Medicine and Surgery, University of Milano, Bicocca, Monza, Italy.
- 700 1_
- $a Kelsey, Karl $u Brown University, Providence, RI, USA.
- 700 1_
- $a McClean, Michael $u Boston University School of Public Health, Boston, MA, USA.
- 700 1_
- $a Ramroth, Heribert $u University of Heidelberg, Germany.
- 700 1_
- $a Chen, Chu $u Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
- 700 1_
- $a Schwartz, Stephen M $u Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
- 700 1_
- $a Vaughan, Thomas L $u Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
- 700 1_
- $a Zheng, Tongzhang $u Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
- 700 1_
- $a Menvielle, Gwenn $u Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique IPLESP, Department of Social Epidemiology, F75012 Paris, France.
- 700 1_
- $a Boccia, Stefania $u Department of Woman and Child Health and Public Health, Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; Sezione di Igiene, Istituto di Sanità Pubblica, Università Cattolica del Sacro Cuore, Roma, Italy.
- 700 1_
- $a Cadoni, Gabriella $u Dipartimento di Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; Istituto di Clinica Otorinolaringoiatrica, Università Cattolica del Sacro Cuore, Roma, Italy.
- 700 1_
- $a Hayes, Richard B $u Division of Epidemiology, New York University School Of Medicine, New York, NY, USA.
- 700 1_
- $a Purdue, Mark $u Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
- 700 1_
- $a Gillison, Maura $u "Thoracic/Head and Neck Medical Oncology", The University of Texas MD Anderson Cancer Center, TX, USA.
- 700 1_
- $a Schantz, Stimson $u New York Eye and Ear Infirmary, New York, NY, USA.
- 700 1_
- $a Yu, Guo-Pei $u Medical Informatics Center, Peking University, China.
- 700 1_
- $a Brenner, Hermann $u Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
- 700 1_
- $a D'Souza, Gypsyamber $u Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
- 700 1_
- $a Gross, Neil D $u Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
- 700 1_
- $a Chuang, Shu-Chun $u Institute of Population Health Sciences, National Health Research Institutes, Taiwan.
- 700 1_
- $a Boffetta, Paolo $u The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- 700 1_
- $a Hashibe, Mia $u Division of Public Health, Department of Family & Preventive Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
- 700 1_
- $a Lee, Yuan-Chin Amy $u Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
- 700 1_
- $a Dal Maso, Luigino $u Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy.
- 773 0_
- $w MED00003631 $t Oral oncology $x 1879-0593 $g Roč. 94, č. - (2019), s. 47-57
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/31178212 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20201125 $b ABA008
- 991 __
- $a 20201214131510 $b ABA008
- 999 __
- $a ok $b bmc $g 1596188 $s 1114545
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2019 $b 94 $c - $d 47-57 $e 20190517 $i 1879-0593 $m Oral oncology $n Oral Oncol $x MED00003631
- GRA __
- $a P01 CA068384 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 DA011386 $p NIDA NIH HHS $2 United States
- GRA __
- $a R01 CA030022 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 ES011740 $p NIEHS NIH HHS $2 United States
- GRA __
- $a R03 TW001500 $p FIC NIH HHS $2 United States
- GRA __
- $a R01 DE016631 $p NIDCR NIH HHS $2 United States
- GRA __
- $a R01 CA100679 $p NCI NIH HHS $2 United States
- GRA __
- $a R03 CA113157 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 CA100264 $p NCI NIH HHS $2 United States
- GRA __
- $a P30 ES010126 $p NIEHS NIH HHS $2 United States
- GRA __
- $a R01 DA011979 $p NIDA NIH HHS $2 United States
- GRA __
- $a R13 CA210555 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 DE013158 $p NIDCR NIH HHS $2 United States
- GRA __
- $a R01 CA078609 $p NCI NIH HHS $2 United States
- GRA __
- $a K07 CA104231 $p NCI NIH HHS $2 United States
- GRA __
- $a T32 CA009142 $p NCI NIH HHS $2 United States
- GRA __
- $a U01 CA096134 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 CA090731 $p NCI NIH HHS $2 United States
- GRA __
- $a R03 CA077954 $p NCI NIH HHS $2 United States
- GRA __
- $a R21 ES011667 $p NIEHS NIH HHS $2 United States
- GRA __
- $a R03 DE016611 $p NIDCR NIH HHS $2 United States
- GRA __
- $a R01 CA048996 $p NCI NIH HHS $2 United States
- GRA __
- $a P50 CA090388 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 DE013110 $p NIDCR NIH HHS $2 United States
- LZP __
- $a Pubmed-20201125
