• Je něco špatně v tomto záznamu ?

Plasma Membrane Domain Patterning and Self-Reinforcing Polarity in Arabidopsis

P. Marhava, AC. Aliaga Fandino, SWH. Koh, A. Jelínková, M. Kolb, DP. Janacek, AS. Breda, P. Cattaneo, UZ. Hammes, J. Petrášek, CS. Hardtke,

. 2020 ; 52 (2) : 223-235.e5. [pub] 20191219

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc20025258

Cell polarity is a key feature in the development of multicellular organisms. For instance, asymmetrically localized plasma-membrane-integral PIN-FORMED (PIN) proteins direct transcellular fluxes of the phytohormone auxin that govern plant development. Fine-tuned auxin flux is important for root protophloem sieve element differentiation and requires the interacting plasma-membrane-associated BREVIS RADIX (BRX) and PROTEIN KINASE ASSOCIATED WITH BRX (PAX) proteins. We observed "donut-like" polar PIN localization in developing sieve elements that depends on complementary, "muffin-like" polar localization of BRX and PAX. Plasma membrane association and polarity of PAX, and indirectly BRX, largely depends on phosphatidylinositol-4,5-bisphosphate. Consistently, mutants in phosphatidylinositol-4-phosphate 5-kinases (PIP5Ks) display protophloem differentiation defects similar to brx mutants. The same PIP5Ks are in complex with BRX and display "muffin-like" polar localization. Our data suggest that the BRX-PAX module recruits PIP5Ks to reinforce PAX polarity and thereby the polarity of all three proteins, which is required to maintain a local PIN minimum.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc20025258
003      
CZ-PrNML
005      
20201222155132.0
007      
ta
008      
201125s2020 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.devcel.2019.11.015 $2 doi
035    __
$a (PubMed)31866202
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Marhava, Petra $u Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland.
245    10
$a Plasma Membrane Domain Patterning and Self-Reinforcing Polarity in Arabidopsis / $c P. Marhava, AC. Aliaga Fandino, SWH. Koh, A. Jelínková, M. Kolb, DP. Janacek, AS. Breda, P. Cattaneo, UZ. Hammes, J. Petrášek, CS. Hardtke,
520    9_
$a Cell polarity is a key feature in the development of multicellular organisms. For instance, asymmetrically localized plasma-membrane-integral PIN-FORMED (PIN) proteins direct transcellular fluxes of the phytohormone auxin that govern plant development. Fine-tuned auxin flux is important for root protophloem sieve element differentiation and requires the interacting plasma-membrane-associated BREVIS RADIX (BRX) and PROTEIN KINASE ASSOCIATED WITH BRX (PAX) proteins. We observed "donut-like" polar PIN localization in developing sieve elements that depends on complementary, "muffin-like" polar localization of BRX and PAX. Plasma membrane association and polarity of PAX, and indirectly BRX, largely depends on phosphatidylinositol-4,5-bisphosphate. Consistently, mutants in phosphatidylinositol-4-phosphate 5-kinases (PIP5Ks) display protophloem differentiation defects similar to brx mutants. The same PIP5Ks are in complex with BRX and display "muffin-like" polar localization. Our data suggest that the BRX-PAX module recruits PIP5Ks to reinforce PAX polarity and thereby the polarity of all three proteins, which is required to maintain a local PIN minimum.
650    _2
$a Arabidopsis $x genetika $x růst a vývoj $x metabolismus $7 D017360
650    _2
$a proteiny huseníčku $x genetika $x metabolismus $7 D029681
650    12
$a buněčná diferenciace $7 D002454
650    _2
$a buněčná membrána $x metabolismus $7 D002462
650    12
$a polarita buněk $7 D016764
650    12
$a regulace genové exprese u rostlin $7 D018506
650    _2
$a mutace $7 D009154
650    _2
$a transkripční faktory paired box $x genetika $x metabolismus $7 D051761
650    _2
$a fosfatasy $x genetika $x metabolismus $7 D010744
650    _2
$a fosfotransferasy s alkoholovou skupinou jako akceptorem $x metabolismus $7 D017853
650    _2
$a kořeny rostlin $x genetika $x růst a vývoj $x metabolismus $7 D018517
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Aliaga Fandino, Ana Cecilia $u Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland.
700    1_
$a Koh, Samuel W H $u Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland.
700    1_
$a Jelínková, Adriana $u Institute of Experimental Botany, Czech Acad Sci, Rozvojová 263, 165 02 Praha 6, Czech Republic.
700    1_
$a Kolb, Martina $u Plant Systems Biology, Technical University of Munich, 85354 Freising, Germany.
700    1_
$a Janacek, Dorina P $u Plant Systems Biology, Technical University of Munich, 85354 Freising, Germany.
700    1_
$a Breda, Alice S $u Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland.
700    1_
$a Cattaneo, Pietro $u Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland.
700    1_
$a Hammes, Ulrich Z $u Plant Systems Biology, Technical University of Munich, 85354 Freising, Germany.
700    1_
$a Petrášek, Jan $u Institute of Experimental Botany, Czech Acad Sci, Rozvojová 263, 165 02 Praha 6, Czech Republic.
700    1_
$a Hardtke, Christian S $u Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland. Electronic address: christian.hardtke@unil.ch.
773    0_
$w MED00173658 $t Developmental cell $x 1878-1551 $g Roč. 52, č. 2 (2020), s. 223-235.e5
856    41
$u https://pubmed.ncbi.nlm.nih.gov/31866202 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20201125 $b ABA008
991    __
$a 20201222155128 $b ABA008
999    __
$a ok $b bmc $g 1599403 $s 1115944
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 52 $c 2 $d 223-235.e5 $e 20191219 $i 1878-1551 $m Developmental cell $n Dev Cell $x MED00173658
LZP    __
$a Pubmed-20201125

Najít záznam

Citační ukazatele

Možnosti archivace