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EAU-ESMO consensus statements on the management of advanced and variant bladder cancer-an international collaborative multi-stakeholder effort: under the auspices of the EAU and ESMO Guidelines Committees†

A. Horwich, M. Babjuk, J. Bellmunt, HM. Bruins, TM. De Reijke, M. De Santis, S. Gillessen, N. James, S. Maclennan, J. Palou, T. Powles, MJ. Ribal, SF. Shariat, T. Van Der Kwast, E. Xylinas, N. Agarwal, T. Arends, A. Bamias, A. Birtle, PC. Black,...

. 2019 ; 30 (11) : 1697-1727. [pub] 20191101

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc20025517

BACKGROUND: Although guidelines exist for advanced and variant bladder cancer management, evidence is limited/conflicting in some areas and the optimal approach remains controversial. OBJECTIVE: To bring together a large multidisciplinary group of experts to develop consensus statements on controversial topics in bladder cancer management. DESIGN: A steering committee compiled proposed statements regarding advanced and variant bladder cancer management which were assessed by 113 experts in a Delphi survey. Statements not reaching consensus were reviewed; those prioritised were revised by a panel of 45 experts before voting during a consensus conference. SETTING: Online Delphi survey and consensus conference. PARTICIPANTS: The European Association of Urology (EAU), the European Society for Medical Oncology (ESMO), experts in bladder cancer management. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Statements were ranked by experts according to their level of agreement: 1-3 (disagree), 4-6 (equivocal), 7-9 (agree). A priori (level 1) consensus was defined as ≥70% agreement and ≤15% disagreement, or vice versa. In the Delphi survey, a second analysis was restricted to stakeholder group(s) considered to have adequate expertise relating to each statement (to achieve level 2 consensus). RESULTS AND LIMITATIONS: Overall, 116 statements were included in the Delphi survey. Of these, 33 (28%) statements achieved level 1 consensus and 49 (42%) statements achieved level 1 or 2 consensus. At the consensus conference, 22 of 27 (81%) statements achieved consensus. These consensus statements provide further guidance across a broad range of topics, including the management of variant histologies, the role/limitations of prognostic biomarkers in clinical decision making, bladder preservation strategies, modern radiotherapy techniques, the management of oligometastatic disease and the evolving role of checkpoint inhibitor therapy in metastatic disease. CONCLUSIONS: These consensus statements provide further guidance on controversial topics in advanced and variant bladder cancer management until a time where further evidence is available to guide our approach.

2nd Propaedeutic Dept of Internal Medicine Medical School National and Kapodistrian University of Athens Athens Greece

Academic Urology Unit University of Aberdeen Aberdeen UK

Barts Cancer Institute Queen Mary University of London London UK

Brighton and Sussex Medical School Brighton UK

Cancer Sciences Unit University of Southampton Southampton UK

Cancer Treatment Centre Sorlandet Hospital Kristiansand Norway

Clinica HematoOncologica Bonadona Prevenir Universidad Metropolitana Clinica Club de Leones Barranquilla Colombia

CRUK MRC Oxford Institute for Radiation Oncology University of Oxford Oxford UK

Département de Médecine Oncologique Gustave Roussy INSERM U981 Université Paris Sud Université Paris Saclay Villejuif France

Department Innere Medizin Abteilung Onkologie und Hämatologie Kantonsspital Graubünden Chur Switzerland

Department of Biomedical Sciences Humanitas University Milan

Department of Cancer Medicine Hôpital Saint Louis Paris

Department of Cell and Molecular Biology George Emil Palade University of Medicine Pharmacy Science and Technology of Targu Mures Targu Mures Romania

Department of Clinical Oncology Leiden University Medical Center Leiden

Department of Clinical Oncology The Royal Marsden NHS Foundation Trust London UK

Department of Imaging and Nuclear Medicine Royal Sussex County Hospital Brighton

Department of Medical Oncology and Hematology University Hospital Zürich Zürich Switzerland

Department of Medical Oncology Centre Georges François Leclerc Dijon France

Department of Medical Oncology Istituto Nazionale Tumori of Milan Milan Italy

Department of Medicine Memorial Sloan Kettering Cancer Center New York

Department of Medicine University of Melbourne Melbourne

Department of Nuclear Medicine Policlinico S Orsola University of Bologna Bologna Italy

Department of Nuclear Medicine Universitätsklinikum Essen Essen Germany

Department of Oncology Akershus University Hospital Lørenskog

Department of Oncology and Hemato oncology Università degli Studi di Milano Fondazione IRCCS Istituto Nazionale dei Tumori Milan Italy

Department of Oncology and Hemato oncology University of Milan Milan

Department of Oncology Hospital Universitario San Roque Canarias

Department of Oncology Rigshospitalet University Hospital of Copenhagen Copenhagen Denmark

Department of Pathology Erasmus Medical Center Rotterdam The Netherlands

Department of Pathology Tenon Hospital HUEP Paris

Department of Radiation Oncology Amsterdam University Medical Centers University of Amsterdam Amsterdam

Department of Radiation Oncology Eberhard Karls University Tübingen Germany

Department of Radiation Oncology Europe Hospitals Brussels Brussels Belgium

Department of Radiation Oncology Gustave Roussy Institute Villejuif France

Department of Radiation Oncology Radboud University Medical Center Nijmegen The Netherlands

Department of Radiation Oncology University Hospital Ulm Ulm Germany

Department of Radiology and Nuclear Medicine Division of Genitourinary Radiology and Mammography Ghent University Hospital Ghent

Department of Radiology and Nuclear Medicine Radboud University Medical Center Nijmegen The Netherlands

Department of Radiology and Nuclear Medicine Rijnstate Hospital Arnhem The Netherlands

Department of Radiology Copenhagen University Hospital Herlev and Gentofte Herlev Denmark

Department of Radiotherapy Institut Bergonié Bordeaux France

Department of Radiotherapy Oncology Ghent University Hospital Ghent Belgium

Department of Surgery Austin Health University of Melbourne Melbourne

Department of Surgery Faculty of Medicine Nursing and Health Sciences Monash University Clayton Australia

Department of Surgical and Perioperative Sciences Urology and Andrology Umeå University Umeå Sweden

Department of Urologic Sciences Vancouver Prostate Centre University of British Columbia Vancouver Canada

Department of Urology Aberdeen Royal Infirmary Aberdeen UK

Department of Urology Amsterdam University Medical Centers University of Amsterdam Amsterdam The Netherlands

Department of Urology and Paediatric Urology University Hospital of Würzburg Julius Maximillians University Würzburg Germany

Department of Urology Auckland City Hospital Auckland New Zealand

Department of Urology Bichat Claude Bernard Hospital Assistance Publique Hôpitaux de Paris Paris

Department of Urology Caritas St Josef Medical Center University of Regensburg Regensburg Germany

Department of Urology Centro Hospitalar São João Porto

Department of Urology Charité University Hospital Berlin Germany

Department of Urology Division of Surgery The University of Texas MD Anderson Cancer Center Houston USA

Department of Urology Eberhard Karls University Tübingen Tübingen Germany

Department of Urology Erasmus University Medical Center Rotterdam The Netherlands

Department of Urology Fundació Puigvert Universitat Autònoma de Barcelona Barcelona Spain

Department of Urology Ghent University Hospital Ghent Belgium

Department of Urology Hospital Foch University of Versailles Saint Quentin en Yvelines Suresnes France

Department of Urology Hospital Universitario Fundación de Alcorcón Madrid Spain

Department of Urology Inselspital Bern University Hospital Berne Switzerland

Department of Urology Karolinska Institutet Stockholm Sweden

Department of Urology Luzerner Kantonsspital Luzern Switzerland

Department of Urology Medical University of Vienna Vienna Austria

Department of Urology Medizinische Universität Graz Graz Austria

Department of Urology Pediatric Urology and Urologic Oncology Kliniken Essen Mitte Essen Germany

Department of Urology Radboud University Medical Center Nijmegen

Department of Urology Rechts der Isar Medical Center Technical University of Munich Munich Germany

Department of Urology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark

Department of Urology Royal Surrey County Hospital Guildford UK

Department of Urology Ruhr University Bochum Marien Hospital Herne Germany

Department of Urology Saint John Emergency Clinical Hospital Bucharest Romania

Department of Urology Sorbonne Université GRC n°5 ONCOTYPE URO AP HP Hôpital Pitié Salpêtrière Paris

Department of Urology Tampere University Hospital Tampere Finland

Department of Urology University Hospital La Paz Madrid Spain

Department of Urology University Hospital of Turku Turku Finland

Department of Urology University Hospitals Leuven Leuven Belgium

Department of Urology University Medical Center Groningen University of Groningen Groningen The Netherlands

Department of Urology University Medical Center Hamburg Eppendorf Hamburg

Department of Urology University Medical Center Utrecht Utrecht The Netherlands

Department of Urology University of California San Diego Pathology La Jolla USA

Department of Urology University of Texas Southwestern Medical Center Dallas USA

Department of Urology Urological Research Institute Milan

Department of Urology UWA Medical School University of Western Australia Perth Australia

Department of Urology Weill Cornell Medical College New York

Department of Urology Westmead Hospital University of Sydney Sydney Australia

Depatment of Urology 2nd Faculty of Medicine Hospital Motol Charles University Prague Czech Republic

Division of Cancer Sciences University of Manchester Manchester

Division of Oncology and Haematology Kantonsspital St Gallen St Gallen

Division of Radiotherapy and Imaging The Institute of Cancer Research London

Division of Radiotherapy IEO European Institute of Oncology IRCCS Milan Italy

Division of Urology IREC Cliniques Universitaires Saint Luc UCL Brussels Belgium

Division of Urology Molinette Hospital University of Studies of Torino Torino Italy

Eastern Health Clinical School Monash University Melbourne Australia

EAU Guidelines Office Arnhem The Netherlands

Emeritus Professor of Radiation Oncology Grenoble Alpes University Grenoble France

Emeritus Professor The Institute of Cancer Research London UK

Faculty of Medicine University of Oslo Oslo Norway

Harvard Medical School Boston USA

Hospices Civils de Lyon Service d'Imagerie Urinaire et Vasculaire Hôpital Edouard Herriot Lyon

Humanitas Research Hospital Milan Italy

Huntsman Cancer Institute University of Utah Salt Lake City USA

Icahn School of Medicine Mount Sinai Health System New York City USA

IMIM Hospital del Mar Medical Research Institute Barcelona Spain

Institute for Urology and Reproductive Health 1 M Sechenov 1st Moscow State Medical University Moscow Russia

Institute of Cancer and Genomic Sciences University of Birmingham Birmingham

Institute of Cancer Sciences College of Medicine Veterinary and Life Sciences University of Glasgow Glasgow UK

Institute of Pathology Friedrich Alexander University Erlangen Nürnberg Erlangen Germany

Leeds Institute of Medical Research University of Leeds Leeds UK

Life and Health Sciences Research Institute School of Medicine University of Minho Braga Portugal

Medical Oncology Department 12 de Octubre University Hospital Madrid Spain

Molecular Imaging Program National Cancer Institute Bethesda USA

Monash University Melbourne Australia

Mount Vernon Centre for Cancer Treatment London UK

Paris Descartes University Paris France

Radiation Oncology Department Centre Hospitalier Régional Universitaire Jean Minjoz of Besançon INSERM UMR 1098 Besançon France

Radiation Oncology Department Centre Hospitalier Universitaire Vaudois Université de Lausanne Lausanne Switzerland

Rosemere Cancer Centre Lancashire Teaching Hospitals Preston UK

Servicio de Urología Fundación Instituto Valenciano de Oncología Valencia Spain

Sorbonne University Paris France

The Christie NHS Foundation Trust Manchester UK

The Royal Free NHS Trust London

UMC Utrecht Cancer Center MS Oncologic Urology Utrecht The Netherlands

Universidad Fernando Pessoa Canarias Spain

Université de Lyon Université Lyon 1 Faculté de Médecine Lyon Est Lyon France

University Hospitals Birmingham NHS Foundation Trust Birmingham

University of Bern Bern Switzerland

Uro Oncology Unit Hospital Clinic University of Barcelona Barcelona Spain

Urology Department Canisius Wilhelmina Ziekenhuis Nijmegen Nijmegen The Netherlands

Urology Service Department of Urology Memorial Sloan Kettering Cancer Center New York USA

Vita Salute University San Raffaele Scientific Institute Milan Italy

Weill Cornell Medical College New York USA

Citace poskytuje Crossref.org

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$a BACKGROUND: Although guidelines exist for advanced and variant bladder cancer management, evidence is limited/conflicting in some areas and the optimal approach remains controversial. OBJECTIVE: To bring together a large multidisciplinary group of experts to develop consensus statements on controversial topics in bladder cancer management. DESIGN: A steering committee compiled proposed statements regarding advanced and variant bladder cancer management which were assessed by 113 experts in a Delphi survey. Statements not reaching consensus were reviewed; those prioritised were revised by a panel of 45 experts before voting during a consensus conference. SETTING: Online Delphi survey and consensus conference. PARTICIPANTS: The European Association of Urology (EAU), the European Society for Medical Oncology (ESMO), experts in bladder cancer management. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Statements were ranked by experts according to their level of agreement: 1-3 (disagree), 4-6 (equivocal), 7-9 (agree). A priori (level 1) consensus was defined as ≥70% agreement and ≤15% disagreement, or vice versa. In the Delphi survey, a second analysis was restricted to stakeholder group(s) considered to have adequate expertise relating to each statement (to achieve level 2 consensus). RESULTS AND LIMITATIONS: Overall, 116 statements were included in the Delphi survey. Of these, 33 (28%) statements achieved level 1 consensus and 49 (42%) statements achieved level 1 or 2 consensus. At the consensus conference, 22 of 27 (81%) statements achieved consensus. These consensus statements provide further guidance across a broad range of topics, including the management of variant histologies, the role/limitations of prognostic biomarkers in clinical decision making, bladder preservation strategies, modern radiotherapy techniques, the management of oligometastatic disease and the evolving role of checkpoint inhibitor therapy in metastatic disease. CONCLUSIONS: These consensus statements provide further guidance on controversial topics in advanced and variant bladder cancer management until a time where further evidence is available to guide our approach.
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$a Babjuk, M $u Depatment of Urology, 2nd Faculty of Medicine, Hospital Motol, Charles University, Prague, Czech Republic; Department of Urology, Medical University of Vienna, Vienna, Austria.
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$a Bellmunt, J $u IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; Harvard Medical School, Boston, USA.
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$a Bruins, H M $u Department of Urology, Radboud University Medical Center, Nijmegen.
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$a De Reijke, T M $u Department of Urology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
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$a De Santis, M $u Department of Urology, Medical University of Vienna, Vienna, Austria; Department of Urology, Charité University Hospital, Berlin, Germany.
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$a Gillessen, S $u Division of Cancer Sciences, University of Manchester, Manchester; The Christie NHS Foundation Trust, Manchester, UK; Division of Oncology and Haematology, Kantonsspital St Gallen, St Gallen; University of Bern, Bern, Switzerland.
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$a James, N $u University Hospitals Birmingham NHS Foundation Trust, Birmingham; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham.
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$a Maclennan, S $u Academic Urology Unit, University of Aberdeen, Aberdeen, UK.
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$a Palou, J $u Department of Urology, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain.
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$a Powles, T $u The Royal Free NHS Trust, London; Barts Cancer Institute, Queen Mary University of London, London, UK.
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$a Ribal, M J $u Uro-Oncology Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain.
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$a Shariat, S F $u Depatment of Urology, 2nd Faculty of Medicine, Hospital Motol, Charles University, Prague, Czech Republic; Department of Urology, Medical University of Vienna, Vienna, Austria; Department of Urology, Weill Cornell Medical College, New York; Department of Urology, University of Texas Southwestern Medical Center, Dallas, USA; Institute for Urology and Reproductive Health, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
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$a Van Der Kwast, T $u Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.
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$a Xylinas, E $u Department of Urology, Bichat-Claude Bernard Hospital, Assistance Publique Hôpitaux de Paris, Paris; Paris Descartes University, Paris, France.
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$a Agarwal, N $u Huntsman Cancer Institute, University of Utah (NCI-CCC), Salt Lake City, USA.
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$a Arends, T $u Urology Department, Canisius-Wilhelmina Ziekenhuis Nijmegen, Nijmegen, The Netherlands.
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$a Bamias, A $u 2nd Propaedeutic Dept of Internal Medicine, Medical School, National & Kapodistrian University of Athens, Athens, Greece.
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$a Birtle, A $u Division of Cancer Sciences, University of Manchester, Manchester; Rosemere Cancer Centre, Lancashire Teaching Hospitals, Preston, UK.
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$a Bolla, M $u Emeritus Professor of Radiation Oncology, Grenoble - Alpes University, Grenoble, France.
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$a Boormans, J L $u Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.
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$a Bossi, A $u Department of Radiation Oncology, Gustave Roussy Institute, Villejuif, France.
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$a Briganti, A $u Department of Urology, Urological Research Institute, Milan; Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy.
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$a Brummelhuis, I $u Department of Urology, Radboud University Medical Center, Nijmegen.
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$a Burger, M $u Department of Urology, Caritas-St. Josef Medical Center, University of Regensburg, Regensburg, Germany.
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$a Castellano, D $u Medical Oncology Department, 12 de Octubre University Hospital (CIBERONC), Madrid, Spain.
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$a Cathomas, R $u Department Innere Medizin, Abteilung Onkologie und Hämatologie, Kantonsspital Graubünden, Chur, Switzerland.
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$a Chiti, A $u Department of Biomedical Sciences, Humanitas University, Milan; Humanitas Research Hospital, Milan, Italy.
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$a Choudhury, A $u Division of Cancer Sciences, University of Manchester, Manchester; The Christie NHS Foundation Trust, Manchester, UK.
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$a Compérat, E $u Department of Pathology, Tenon Hospital, HUEP, Paris; Sorbonne University, Paris, France.
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$a Crabb, S $u Cancer Sciences Unit, University of Southampton, Southampton, UK.
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$a Culine, S $u Department of Cancer Medicine, Hôpital Saint Louis, Paris.
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$a De Bari, B $u Radiation Oncology Department, Centre Hospitalier Régional Universitaire "Jean Minjoz" of Besançon, INSERM UMR 1098, Besançon, France; Radiation Oncology Department, Centre Hospitalier Universitaire Vaudois, Université de Lausanne, Lausanne, Switzerland.
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$a DeBlok, W $u Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands.
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$a De Visschere, P J L $u Department of Radiology and Nuclear Medicine, Division of Genitourinary Radiology and Mammography, Ghent University Hospital, Ghent.
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$a Decaestecker, K $u Department of Urology, Ghent University Hospital, Ghent, Belgium.
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$a Dimitropoulos, K $u Department of Urology, Aberdeen Royal Infirmary, Aberdeen, UK.
700    1_
$a Dominguez-Escrig, J L $u Servicio de Urología, Fundación Instituto Valenciano de Oncología, Valencia, Spain.
700    1_
$a Fanti, S $u Department of Nuclear Medicine, Policlinico S Orsola, University of Bologna, Bologna, Italy.
700    1_
$a Fonteyne, V $u Department of Radiotherapy Oncology, Ghent University Hospital, Ghent, Belgium.
700    1_
$a Frydenberg, M $u Department of Surgery, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia.
700    1_
$a Futterer, J J $u Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
700    1_
$a Gakis, G $u Department of Urology and Paediatric Urology, University Hospital of Würzburg, Julius-Maximillians University, Würzburg, Germany.
700    1_
$a Geavlete, B $u Department of Urology, Saint John Emergency Clinical Hospital, Bucharest, Romania.
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$a Gontero, P $u Division of Urology, Molinette Hospital, University of Studies of Torino, Torino, Italy.
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$a Grubmüller, B $u Department of Urology, Medical University of Vienna, Vienna, Austria.
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$a Hafeez, S $u Division of Radiotherapy and Imaging, The Institute of Cancer Research, London; Department of Clinical Oncology, The Royal Marsden NHS Foundation Trust, London, UK.
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$a Hansel, D E $u Department of Urology, University of California, San Diego Pathology, La Jolla, USA.
700    1_
$a Hartmann, A $u Institute of Pathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
700    1_
$a Hayne, D $u Department of Urology, UWA Medical School, University of Western Australia, Perth, Australia.
700    1_
$a Henry, A M $u Leeds Institute of Medical Research, University of Leeds, Leeds, UK.
700    1_
$a Hernandez, V $u Department of Urology, Hospital Universitario Fundación de Alcorcón, Madrid, Spain.
700    1_
$a Herr, H $u Urology Service, Department of Urology, Memorial Sloan Kettering Cancer Center, New York, USA.
700    1_
$a Herrmann, K $u Department of Nuclear Medicine, Universitätsklinikum Essen, Essen, Germany.
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$a Hoskin, P $u Division of Cancer Sciences, University of Manchester, Manchester; The Christie NHS Foundation Trust, Manchester, UK; Mount Vernon Centre for Cancer Treatment, London, UK.
700    1_
$a Huguet, J $u Department of Urology, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain.
700    1_
$a Jereczek-Fossa, B A $u Department of Oncology and Hemato-oncology, University of Milan, Milan; Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Milan, Italy.
700    1_
$a Jones, R $u Institute of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
700    1_
$a Kamat, A M $u Department of Urology - Division of Surgery, The University of Texas, MD Anderson Cancer Center, Houston, USA.
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$a Khoo, V $u Division of Radiotherapy and Imaging, The Institute of Cancer Research, London; Department of Clinical Oncology, The Royal Marsden NHS Foundation Trust, London, UK; Department of Medicine, University of Melbourne, Melbourne; Monash University, Melbourne, Australia.
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$a Kiltie, A E $u CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK.
700    1_
$a Krege, S $u Department of Urology, Pediatric Urology and Urologic Oncology, Kliniken Essen-Mitte, Essen, Germany.
700    1_
$a Ladoire, S $u Department of Medical Oncology, Centre Georges François Leclerc, Dijon, France.
700    1_
$a Lara, P C $u Department of Oncology, Hospital Universitario San Roque, Canarias; Universidad Fernando Pessoa, Canarias, Spain.
700    1_
$a Leliveld, A $u Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
700    1_
$a Linares-Espinós, E $u Department of Urology, University Hospital La Paz, Madrid, Spain.
700    1_
$a Løgager, V $u Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark.
700    1_
$a Lorch, A $u Department of Medical Oncology and Hematology, University Hospital Zürich, Zürich, Switzerland.
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$a Loriot, Y $u Département de Médecine Oncologique, Gustave Roussy, INSERM U981, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
700    1_
$a Meijer, R $u UMC Utrecht Cancer Center, MS Oncologic Urology, Utrecht, The Netherlands.
700    1_
$a Carmen Mir, M $u Servicio de Urología, Fundación Instituto Valenciano de Oncología, Valencia, Spain.
700    1_
$a Moschini, M $u Department of Urology, Luzerner Kantonsspital, Luzern, Switzerland.
700    1_
$a Mostafid, H $u Department of Urology, Royal Surrey County Hospital, Guildford, UK.
700    1_
$a Müller, A-C $u Department of Radiation Oncology, Eberhard Karls University, Tübingen, Germany.
700    1_
$a Müller, C R $u Cancer Treatment Centre, Sorlandet Hospital, Kristiansand, Norway.
700    1_
$a N'Dow, J $u Academic Urology Unit, University of Aberdeen, Aberdeen, UK; Department of Urology, Aberdeen Royal Infirmary, Aberdeen, UK.
700    1_
$a Necchi, A $u Department of Medical Oncology, Istituto Nazionale Tumori of Milan, Milan, Italy.
700    1_
$a Neuzillet, Y $u Department of Urology, Hospital Foch, University of Versailles-Saint-Quentin-en-Yvelines, Suresnes, France.
700    1_
$a Oddens, J R $u Department of Urology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
700    1_
$a Oldenburg, J $u Department of Oncology, Akershus University Hospital, Lørenskog; Faculty of Medicine, University of Oslo, Oslo, Norway.
700    1_
$a Osanto, S $u Department of Clinical Oncology, Leiden University Medical Center, Leiden.
700    1_
$a Oyen, W J G $u Department of Biomedical Sciences, Humanitas University, Milan; Humanitas Research Hospital, Milan, Italy; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Radiology and Nuclear Medicine, Rijnstate Hospital, Arnhem, The Netherlands.
700    1_
$a Pacheco-Figueiredo, L $u Department of Urology, Centro Hospitalar São João, Porto; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
700    1_
$a Pappot, H $u Department of Oncology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
700    1_
$a Patel, M I $u Department of Urology, Westmead Hospital, University of Sydney, Sydney, Australia.
700    1_
$a Pieters, B R $u Department of Radiation Oncology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam.
700    1_
$a Plass, K $u EAU Guidelines Office, Arnhem, The Netherlands.
700    1_
$a Remzi, M $u Department of Urology, Medical University of Vienna, Vienna, Austria.
700    1_
$a Retz, M $u Department of Urology, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany.
700    1_
$a Richenberg, J $u Department of Imaging and Nuclear Medicine, Royal Sussex County Hospital, Brighton; Brighton and Sussex Medical School, Brighton, UK.
700    1_
$a Rink, M $u Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg.
700    1_
$a Roghmann, F $u Department of Urology, Ruhr-University Bochum, Marien Hospital, Herne, Germany.
700    1_
$a Rosenberg, J E $u Department of Medicine, Memorial Sloan Kettering Cancer Center, New York; Weill Cornell Medical College, New York, USA.
700    1_
$a Rouprêt, M $u Department of Urology, Sorbonne Université, GRC n°5, ONCOTYPE-URO, AP-HP, Hôpital Pitié-Salpêtrière, Paris.
700    1_
$a Rouvière, O $u Hospices Civils de Lyon, Service d'Imagerie Urinaire et Vasculaire, Hôpital Edouard Herriot, Lyon; Université de Lyon, Université Lyon 1, Faculté de Médecine Lyon Est, Lyon, France.
700    1_
$a Salembier, C $u Department of Radiation Oncology, Europe Hospitals Brussels, Brussels, Belgium.
700    1_
$a Salminen, A $u Department of Urology, University Hospital of Turku, Turku, Finland.
700    1_
$a Sargos, P $u Department of Radiotherapy, Institut Bergonié, Bordeaux, France.
700    1_
$a Sengupta, S $u Department of Surgery, Austin Health, University of Melbourne, Melbourne; Eastern Health Clinical School, Monash University, Melbourne, Australia.
700    1_
$a Sherif, A $u Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden.
700    1_
$a Smeenk, R J $u Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
700    1_
$a Smits, A $u Department of Urology, Radboud University Medical Center, Nijmegen.
700    1_
$a Stenzl, A $u Department of Urology, Eberhard Karls University Tübingen, Tübingen, Germany.
700    1_
$a Thalmann, G N $u Department of Urology, Inselspital, Bern University Hospital, Berne, Switzerland.
700    1_
$a Tombal, B $u Division of Urology, IREC, Cliniques Universitaires Saint Luc, UCL, Brussels, Belgium.
700    1_
$a Turkbey, B $u Molecular Imaging Program, National Cancer Institute, Bethesda, USA.
700    1_
$a Vahr Lauridsen, S $u Department of Urology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
700    1_
$a Valdagni, R $u Department of Oncology and Hemato-oncology, Università degli Studi di Milano, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
700    1_
$a Van Der Heijden, A G $u Department of Urology, Radboud University Medical Center, Nijmegen.
700    1_
$a Van Poppel, H $u Department of Urology, University Hospitals Leuven, Leuven, Belgium.
700    1_
$a Vartolomei, M D $u Department of Urology, Medical University of Vienna, Vienna, Austria; Department of Cell and Molecular Biology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.
700    1_
$a Veskimäe, E $u Department of Urology, Tampere University Hospital, Tampere, Finland.
700    1_
$a Vilaseca, A $u Uro-Oncology Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain.
700    1_
$a Vives Rivera, F A $u Clinica HematoOncologica Bonadona Prevenir, Universidad Metropolitana, Clinica Club de Leones, Barranquilla, Colombia.
700    1_
$a Wiegel, T $u Department of Radiation Oncology, University Hospital Ulm, Ulm, Germany.
700    1_
$a Wiklund, P $u Icahn School of Medicine, Mount Sinai Health System, New York City, USA; Department of Urology, Karolinska Institutet, Stockholm, Sweden.
700    1_
$a Williams, A $u Department of Urology, Auckland City Hospital, Auckland, New Zealand.
700    1_
$a Zigeuner, R $u Department of Urology, Medizinische Universität Graz, Graz, Austria.
700    1_
$a Witjes, J A $u Department of Urology, Radboud University Medical Center, Nijmegen.
773    0_
$w MED00000432 $t Annals of oncology : official journal of the European Society for Medical Oncology $x 1569-8041 $g Roč. 30, č. 11 (2019), s. 1697-1727
856    41
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