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Complete Nucleotide Sequences of mcr-4.3-Carrying Plasmids in Acinetobacter baumannii Sequence Type 345 of Human and Food Origin from the Czech Republic, the First Case in Europe

I. Bitar, M. Medvecky, T. Gelbicova, V. Jakubu, J. Hrabak, H. Zemlickova, R. Karpiskova, M. Dolejska,

. 2019 ; 63 (10) : . [pub] 20190923

Language English Country United States

Document type Journal Article, Research Support, Non-U.S. Gov't

E-resources Online Full text

NLK Free Medical Journals from 1972 to 6 months ago
Freely Accessible Science Journals from 1995 to 6 months ago
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Here, we describe two plasmids carrying mcr-4.3 in two Acinetobacter baumannii strains isolated from imported food and a clinical sample. The comparative analysis of these plasmids, with two other plasmids reported in the NCBI database, highlighted the common origin of the plasmidic structure carrying mcr-4.3 This is the first case of the mcr-4.3 gene in a A. baumannii strain isolated from a clinical case in Europe. We hypothesize that food import is initiating the spread in Czech Republic.

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$a Gelbicova, Tereza $u Veterinary Research Institute, Brno, Czech Republic.
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$a Jakubu, Vladislav $u National Reference Laboratory for Antibiotics, The National Institute of Public Health, Centre for Epidemiology and Microbiology, Prague, Czech Republic. Department of Clinical Microbiology, Faculty of Medicine and University Hospital, Charles University, Hradec Kralove, Czech Republic.
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