Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Revaluation and lessons learned from the first 9 cases of a Czech uterus transplantation trial: Four deceased donor and 5 living donor uterus transplantations

R. Chmel, M. Novackova, L. Janousek, J. Matecha, Z. Pastor, J. Maluskova, M. Cekal, J. Kristek, M. Olausson, J. Fronek,

. 2019 ; 19 (3) : 855-864. [pub] 20181009

Jazyk angličtina Země Spojené státy americké

Typ dokumentu hodnotící studie, časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc20025918

Grantová podpora
00064203 Ministry of Health - International
Czech Republic - International
Conceptual Development of Research Organization - International
Motol University Hospital, Prague - International

Although uterus transplantation is still in the experimental stage, it has promising potential as a treatment for women with absolute uterine factor infertility based on the childbirths from living donor trials conducted in Sweden and the United States. We report the main characteristics and perioperative and postoperative courses of both recipients and donors following 4 deceased donor and 5 living donor uterus transplantations. Three main priorities differentiate this study from the previously reported uterus transplantations. First, clinical experience with the largest worldwide group of deceased donor uterine transplants is described. Second, in the majority of living donor uterine recipients, only 2 ovarian veins were used for venous blood outflow. All of these recipient procedures were surgically successful, and follow-up posttransplant ultrasound examinations revealed normal uterine blood supply and outflow. Third, in only one living and one deceased donor recipient, the transplanted uterus relied on only 2 uterine veins for venous outflow with a 50% surgical success rate. In all other recipients, 2 uterine and 2 ovarian veins were utilized. Although a successful pregnancy has not yet been achieved, the presented surgical and functional results of our trial are promising.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc20025918
003      
CZ-PrNML
005      
20201222155535.0
007      
ta
008      
201125s2019 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1111/ajt.15096 $2 doi
035    __
$a (PubMed)30151893
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Chmel, Roman $u Transplantation Surgery Department, Institute of Clinical and Experimental Medicine, Prague, Czech Republic. Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
245    10
$a Revaluation and lessons learned from the first 9 cases of a Czech uterus transplantation trial: Four deceased donor and 5 living donor uterus transplantations / $c R. Chmel, M. Novackova, L. Janousek, J. Matecha, Z. Pastor, J. Maluskova, M. Cekal, J. Kristek, M. Olausson, J. Fronek,
520    9_
$a Although uterus transplantation is still in the experimental stage, it has promising potential as a treatment for women with absolute uterine factor infertility based on the childbirths from living donor trials conducted in Sweden and the United States. We report the main characteristics and perioperative and postoperative courses of both recipients and donors following 4 deceased donor and 5 living donor uterus transplantations. Three main priorities differentiate this study from the previously reported uterus transplantations. First, clinical experience with the largest worldwide group of deceased donor uterine transplants is described. Second, in the majority of living donor uterine recipients, only 2 ovarian veins were used for venous blood outflow. All of these recipient procedures were surgically successful, and follow-up posttransplant ultrasound examinations revealed normal uterine blood supply and outflow. Third, in only one living and one deceased donor recipient, the transplanted uterus relied on only 2 uterine veins for venous outflow with a 50% surgical success rate. In all other recipients, 2 uterine and 2 ovarian veins were utilized. Although a successful pregnancy has not yet been achieved, the presented surgical and functional results of our trial are promising.
650    _2
$a mladiství $7 D000293
650    _2
$a dospělí $7 D000328
650    _2
$a klinické zkoušky jako téma $7 D002986
650    12
$a smrt $7 D003643
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a následné studie $7 D005500
650    _2
$a přežívání štěpu $7 D006085
650    _2
$a lidé $7 D006801
650    _2
$a ženská infertilita $x chirurgie $7 D007247
650    _2
$a žijící dárci $x zásobování a distribuce $7 D019520
650    _2
$a lidé středního věku $7 D008875
650    _2
$a transplantace orgánů $x metody $7 D016377
650    _2
$a prognóza $7 D011379
650    _2
$a dárci tkání $x zásobování a distribuce $7 D014019
650    _2
$a odběr tkání a orgánů $x metody $7 D020858
650    _2
$a uterus $x transplantace $7 D014599
650    _2
$a mladý dospělý $7 D055815
651    _2
$a Česká republika $7 D018153
655    _2
$a hodnotící studie $7 D023362
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Novackova, Marta $u Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
700    1_
$a Janousek, Libor $u Transplantation Surgery Department, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
700    1_
$a Matecha, Jan $u Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
700    1_
$a Pastor, Zlatko $u Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
700    1_
$a Maluskova, Jana $u Department of Pathology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
700    1_
$a Cekal, Milos $u Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
700    1_
$a Kristek, Jakub $u Transplantation Surgery Department, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
700    1_
$a Olausson, Michael $u Transplantation Surgery Department, Sahlgrenska University Hospital, Gothenburg, Sweden.
700    1_
$a Fronek, Jiri $u Transplantation Surgery Department, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
773    0_
$w MED00006447 $t American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons $x 1600-6143 $g Roč. 19, č. 3 (2019), s. 855-864
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30151893 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20201125 $b ABA008
991    __
$a 20201222155531 $b ABA008
999    __
$a ok $b bmc $g 1600063 $s 1116604
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2019 $b 19 $c 3 $d 855-864 $e 20181009 $i 1600-6143 $m American journal of transplantation $n Am J Transplant $x MED00006447
GRA    __
$a 00064203 $p Ministry of Health $2 International
GRA    __
$p Czech Republic $2 International
GRA    __
$p Conceptual Development of Research Organization $2 International
GRA    __
$p Motol University Hospital, Prague $2 International
LZP    __
$a Pubmed-20201125
Zpět

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace