Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Juvenile hormone controls ovarian development in female Anopheles albimanus mosquitoes

S. Hernández-Martínez, V. Cardoso-Jaime, M. Nouzova, V. Michalkova, CE. Ramirez, F. Fernandez-Lima, FG. Noriega,

. 2019 ; 9 (1) : 2127. [pub] 20190214

Language English Country Great Britain

Document type Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc20025940

Grant support
R01 AI045545 NIAID NIH HHS - United States

Anophelinae mosquitoes are vectors of human malaria, a disease that infects hundreds of millions of people and causes almost 600,000 fatalities annually. Despite their medical importance, laboratory studies on key aspects of Anophelinae reproductive biology have been limited, and in particular, relatively little is known about the role of juvenile hormone (JH) in the control of female reproduction. The study presented here attempts to fill a gap of knowledge in our understanding of the JH control of ovarian development in female Anophelinae mosquitoes, using Anopheles albimanus as a model. Our studies revealed that JH controls the tempo of maturation of primary follicles in An. albimanus in a similar manner to that previously described in Aedes aegypti. At adult eclosion JH hemolymph titer was low, increased in 1-day old sugar-fed insects, and decreased in blood fed individuals. JH titers decreased if An. albimanus females were starved, and were reduced if insects emerged with low teneral reserves, precluding previtellogenic ovarian development. However, absolute hemolymph titers were lower than Ae. aegypti. Decapitation experiments suggested that if teneral reserves are sufficient, factors from the head activate JH synthesis by the corpora allata (CA) during the first 9-12 h after adult emergence. In conclusion, our studies support the hypothesis that JH controls previtellogenic ovarian development in female An. albimanus mosquitoes, in a similar manner that have been described in Culicinae.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc20025940
003      
CZ-PrNML
005      
20201222154208.0
007      
ta
008      
201125s2019 xxk f 000 0|eng||
009      
AR
024    7_
$a 10.1038/s41598-019-38631-6 $2 doi
035    __
$a (PubMed)30765796
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxk
100    1_
$a Hernández-Martínez, Salvador $u Centro de Investigaciones Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.
245    10
$a Juvenile hormone controls ovarian development in female Anopheles albimanus mosquitoes / $c S. Hernández-Martínez, V. Cardoso-Jaime, M. Nouzova, V. Michalkova, CE. Ramirez, F. Fernandez-Lima, FG. Noriega,
520    9_
$a Anophelinae mosquitoes are vectors of human malaria, a disease that infects hundreds of millions of people and causes almost 600,000 fatalities annually. Despite their medical importance, laboratory studies on key aspects of Anophelinae reproductive biology have been limited, and in particular, relatively little is known about the role of juvenile hormone (JH) in the control of female reproduction. The study presented here attempts to fill a gap of knowledge in our understanding of the JH control of ovarian development in female Anophelinae mosquitoes, using Anopheles albimanus as a model. Our studies revealed that JH controls the tempo of maturation of primary follicles in An. albimanus in a similar manner to that previously described in Aedes aegypti. At adult eclosion JH hemolymph titer was low, increased in 1-day old sugar-fed insects, and decreased in blood fed individuals. JH titers decreased if An. albimanus females were starved, and were reduced if insects emerged with low teneral reserves, precluding previtellogenic ovarian development. However, absolute hemolymph titers were lower than Ae. aegypti. Decapitation experiments suggested that if teneral reserves are sufficient, factors from the head activate JH synthesis by the corpora allata (CA) during the first 9-12 h after adult emergence. In conclusion, our studies support the hypothesis that JH controls previtellogenic ovarian development in female An. albimanus mosquitoes, in a similar manner that have been described in Culicinae.
650    _2
$a zvířata $7 D000818
650    _2
$a Anopheles $x účinky léků $x růst a vývoj $7 D000852
650    _2
$a corpora allata $x cytologie $x účinky léků $7 D003335
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a hemolymfa $x účinky léků $7 D006458
650    _2
$a juvenilní hormony $x farmakologie $7 D007605
650    _2
$a ovariální folikul $x cytologie $x účinky léků $7 D006080
650    _2
$a rozmnožování $7 D012098
655    _2
$a časopisecké články $7 D016428
655    _2
$a Research Support, N.I.H., Extramural $7 D052061
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Cardoso-Jaime, Víctor $u Centro de Investigaciones Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.
700    1_
$a Nouzova, Marcela $u Department of Biological Sciences and Biomolecular Science Institute, Florida International University, Miami, FL, USA. Institute of Parasitology, Biology Centre CAS, Ceske, Budejovice, Czech Republic.
700    1_
$a Michalkova, Veronika $u Department of Biological Sciences and Biomolecular Science Institute, Florida International University, Miami, FL, USA.
700    1_
$a Ramirez, Cesar E $u Department of Chemistry and Biochemistry, Florida International University, Miami, USA.
700    1_
$a Fernandez-Lima, Francisco $u Department of Chemistry and Biochemistry, Florida International University, Miami, USA.
700    1_
$a Noriega, Fernando G $u Department of Biological Sciences and Biomolecular Science Institute, Florida International University, Miami, FL, USA. noriegaf@fiu.edu.
773    0_
$w MED00182195 $t Scientific reports $x 2045-2322 $g Roč. 9, č. 1 (2019), s. 2127
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30765796 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20201125 $b ABA008
991    __
$a 20201222154204 $b ABA008
999    __
$a ok $b bmc $g 1600085 $s 1116626
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2019 $b 9 $c 1 $d 2127 $e 20190214 $i 2045-2322 $m Scientific reports $n Sci Rep $x MED00182195
GRA    __
$a R01 AI045545 $p NIAID NIH HHS $2 United States
LZP    __
$a Pubmed-20201125
Back

Find record

Citation metrics

Archiving options