• Something wrong with this record ?

Viral Pandemics of the Last Four Decades: Pathophysiology, Health Impacts and Perspectives

S. Roychoudhury, A. Das, P. Sengupta, S. Dutta, S. Roychoudhury, AP. Choudhury, ABF. Ahmed, S. Bhattacharjee, P. Slama,

. 2020 ; 17 (24) : . [pub] 20201215

Language English Country Switzerland

Document type Historical Article, Journal Article, Review

Persistent link   https://www.medvik.cz/link/bmc20027577

The twenty-first century has witnessed some of the deadliest viral pandemics with far-reaching consequences. These include the Human Immunodeficiency Virus (HIV) (1981), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) (2002), Influenza A virus subtype H1N1 (A/H1N1) (2009), Middle East Respiratory Syndrome Coronavirus (MERS-CoV) (2012) and Ebola virus (2013) and the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) (2019-present). Age- and gender-based characterizations suggest that SARS-CoV-2 resembles SARS-CoV and MERS-CoV with regard tohigher fatality rates in males, and in the older population with comorbidities. The invasion-mechanism of SARS-CoV-2 and SARS-CoV, involves binding of its spike protein with angiotensin-converting enzyme 2 (ACE2) receptors; MERS-CoV utilizes dipeptidyl peptidase 4 (DPP4), whereas H1N1 influenza is equipped with hemagglutinin protein. The viral infections-mediated immunomodulation, and progressive inflammatory state may affect the functions of several other organs. Although no effective commercial vaccine is available for any of the viruses, those against SARS-CoV-2 are being developed at an unprecedented speed. Until now, only Pfizer/BioNTech's vaccine has received temporary authorization from the UK Medicines and Healthcare products Regulatory Agency. Given the frequent emergence of viral pandemics in the 21st century, proper understanding of their characteristics and modes of action are essential to address the immediate and long-term health consequences.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc20027577
003      
CZ-PrNML
005      
20210114152110.0
007      
ta
008      
210105s2020 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/ijerph17249411 $2 doi
035    __
$a (PubMed)33333995
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Roychoudhury, Shubhadeep $u Department of Life Science and Bioinformatics, Assam University, Silchar 788011, India.
245    10
$a Viral Pandemics of the Last Four Decades: Pathophysiology, Health Impacts and Perspectives / $c S. Roychoudhury, A. Das, P. Sengupta, S. Dutta, S. Roychoudhury, AP. Choudhury, ABF. Ahmed, S. Bhattacharjee, P. Slama,
520    9_
$a The twenty-first century has witnessed some of the deadliest viral pandemics with far-reaching consequences. These include the Human Immunodeficiency Virus (HIV) (1981), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) (2002), Influenza A virus subtype H1N1 (A/H1N1) (2009), Middle East Respiratory Syndrome Coronavirus (MERS-CoV) (2012) and Ebola virus (2013) and the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) (2019-present). Age- and gender-based characterizations suggest that SARS-CoV-2 resembles SARS-CoV and MERS-CoV with regard tohigher fatality rates in males, and in the older population with comorbidities. The invasion-mechanism of SARS-CoV-2 and SARS-CoV, involves binding of its spike protein with angiotensin-converting enzyme 2 (ACE2) receptors; MERS-CoV utilizes dipeptidyl peptidase 4 (DPP4), whereas H1N1 influenza is equipped with hemagglutinin protein. The viral infections-mediated immunomodulation, and progressive inflammatory state may affect the functions of several other organs. Although no effective commercial vaccine is available for any of the viruses, those against SARS-CoV-2 are being developed at an unprecedented speed. Until now, only Pfizer/BioNTech's vaccine has received temporary authorization from the UK Medicines and Healthcare products Regulatory Agency. Given the frequent emergence of viral pandemics in the 21st century, proper understanding of their characteristics and modes of action are essential to address the immediate and long-term health consequences.
650    _2
$a COVID-19 $7 D000086382
650    _2
$a komorbidita $7 D015897
650    _2
$a virus Ebola $7 D029043
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a HIV $7 D006678
650    _2
$a dějiny 20. století $7 D049673
650    _2
$a dějiny 21. století $7 D049674
650    _2
$a lidé $7 D006801
650    _2
$a virus chřipky A, podtyp H1N1 $7 D053118
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a koronavirus MERS $7 D065207
650    _2
$a pandemie $x dějiny $7 D058873
650    _2
$a veřejné zdravotnictví $7 D011634
650    _2
$a virus SARS $7 D045473
650    _2
$a SARS-CoV-2 $7 D000086402
650    _2
$a virové nemoci $x epidemiologie $x patofyziologie $7 D014777
655    _2
$a historické články $7 D016456
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Das, Anandan $u Department of Life Science and Bioinformatics, Assam University, Silchar 788011, India.
700    1_
$a Sengupta, Pallav $u Department of Physiology, Faculty of Medicine and Biomedical Sciences, MAHSA University, SP2, Bandar Saujana Putra, Jenjarom, Selangor 42610, Malaysia.
700    1_
$a Dutta, Sulagna $u Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, MAHSA University, SP2, Bandar Saujana Putra, Jenjarom, Selangor 42610, Malaysia.
700    1_
$a Roychoudhury, Shatabhisha $u Department of Microbiology, R. G. Kar Medical College and Hospital, Kolkata 700004, India. Health Centre, Assam University, Silchar 788011, India.
700    1_
$a Choudhury, Arun Paul $u Department of Obstetrics and Gynecology, Silchar Medical College and Hospital, Silchar 788014, India.
700    1_
$a Ahmed, A B Fuzayel $u Department of Obstetrics and Gynecology, Silchar Medical College and Hospital, Silchar 788014, India.
700    1_
$a Bhattacharjee, Saumendra $u Department of Pathology, Silchar Medical College and Hospital, Silchar 788014, India.
700    1_
$a Slama, Petr $u Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
773    0_
$w MED00176090 $t International journal of environmental research and public health $x 1660-4601 $g Roč. 17, č. 24 (2020)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/33333995 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20210105 $b ABA008
991    __
$a 20210114152108 $b ABA008
999    __
$a ok $b bmc $g 1607912 $s 1118757
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 17 $c 24 $e 20201215 $i 1660-4601 $m International journal of environmental research and public health $n Int. j. environ. res. public health $x MED00176090
LZP    __
$a Pubmed-20210105

Find record

Citation metrics

Archiving options