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The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis

M. Samec, A. Liskova, L. Koklesova, SM. Samuel, R. Murin, P. Zubor, J. Bujnak, TK. Kwon, D. Büsselberg, R. Prosecky, M. Caprnda, L. Rodrigo, R. Ciccocioppo, P. Kruzliak, P. Kubatka,

. 2020 ; 146 (12) : 3137-3154. [pub] 20201015

Jazyk angličtina Země Německo

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc20027608

Grantová podpora
VEGA 1/0136/19 Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

E-zdroje Online Plný text

NLK ProQuest Central od 1997-01-01 do Před 1 rokem
Medline Complete (EBSCOhost) od 2003-04-01 do Před 1 rokem
Health & Medicine (ProQuest) od 1997-01-01 do Před 1 rokem
Public Health Database (ProQuest) od 1997-01-01 do Před 1 rokem
Springer Nature OA/Free Journals od 1904-02-01

The role of immune system in carcinogenesis represents fundamental events associated with cancer eradication; however, tumor evolution is connected with various mechanisms of tumor evasion and progression of cancer. Based on recent evidence, phytochemicals are directly associated with immunomodulation of the innate and adaptive immunity via different mechanisms of action including stimulation and amplification of immune cells, humoral compartments, and associated molecules. This comprehensive study focuses on immunomodulating potential of phytochemicals (mixture in plants or separately such as individual phytochemical) and their impact on regulation of immune response during cancer development, immune tolerance, and immune escape. Clinical application of phytochemicals as modulators of host immunity against cancer may represent perspective approach in anticancer therapy.

Citace poskytuje Crossref.org

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