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Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures

J. Tan, J. Spada, C. Orlandi, M. Kerscher, M. Anfilova, S. Abdulla, A. Floriánová, K. Preisz, A. Altmayer, C. Delva, D. Kerob, M. Goldobina, M. Arenbergerová, S. Tuz, E. Araviiskaia,

. 2020 ; 19 (3) : 682-688. [pub] 20191203

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články, multicentrická studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc20028453

Grantová podpora
Laboratoires Vichy International

INTRODUCTION: M89, containing 89% of Vichy mineralizing water and hyaluronic acid, has been developed to reinforce the skin barrier and to improve skin quality. AIM: To assess efficacy and tolerability of M89. METHOD: Observational survey of subjects with facial dermatoses or after esthetic procedures. M89 served as adjunct to conventional therapy. Clinician assessments of erythema, desquamation, irritation and patient-reported dryness, burning, itching, and stinging/tingling were conducted at baseline and 4 weeks. At 1 week and 4 weeks, patient assessed tolerance and satisfaction with M89. RESULTS: A total of 1630 subjects participated; 92.5% were females. Mean age was 41.1 ± 11.3 years. Dermatological indications accounted for 32.5%, procedures for 67.5%. At 4 weeks, in subjects with dermatoses, erythema had resolved or improved in 68.0%, desquamation in 83.4%, and irritation in 93.3%. Dryness, burning, itching, and stinging/tingling scores had decreased by 63.8%, 81.8%, 70.9%, and 85.2%, respectively (all P ≤ .0001); 75.7% considered that their skin was sufficiently hydrated. In the procedure group, erythema had resolved or improved in 72.5%, desquamation in 75.2%, and irritation in 88.1%. Dryness, burning, itching, and stinging/tingling scores had decreased by 62.1%, 78.8%, 70.0%, and 84.2%, respectively (all P ≤ .0001); 74.1% considered that their skin was sufficiently hydrated. Almost all subjects reported soothed skin and satisfaction with product texture. Subject and investigator satisfaction was very high. CONCLUSION: M89 significantly improves skin signs and symptoms after 4 weeks of continued use with no tolerance issues in subjects with dermatological indications. Moreover, subjects who have had recently undergone esthetic procedures M89 allowed a satisfying skin recovery.

Citace poskytuje Crossref.org

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$a INTRODUCTION: M89, containing 89% of Vichy mineralizing water and hyaluronic acid, has been developed to reinforce the skin barrier and to improve skin quality. AIM: To assess efficacy and tolerability of M89. METHOD: Observational survey of subjects with facial dermatoses or after esthetic procedures. M89 served as adjunct to conventional therapy. Clinician assessments of erythema, desquamation, irritation and patient-reported dryness, burning, itching, and stinging/tingling were conducted at baseline and 4 weeks. At 1 week and 4 weeks, patient assessed tolerance and satisfaction with M89. RESULTS: A total of 1630 subjects participated; 92.5% were females. Mean age was 41.1 ± 11.3 years. Dermatological indications accounted for 32.5%, procedures for 67.5%. At 4 weeks, in subjects with dermatoses, erythema had resolved or improved in 68.0%, desquamation in 83.4%, and irritation in 93.3%. Dryness, burning, itching, and stinging/tingling scores had decreased by 63.8%, 81.8%, 70.9%, and 85.2%, respectively (all P ≤ .0001); 75.7% considered that their skin was sufficiently hydrated. In the procedure group, erythema had resolved or improved in 72.5%, desquamation in 75.2%, and irritation in 88.1%. Dryness, burning, itching, and stinging/tingling scores had decreased by 62.1%, 78.8%, 70.0%, and 84.2%, respectively (all P ≤ .0001); 74.1% considered that their skin was sufficiently hydrated. Almost all subjects reported soothed skin and satisfaction with product texture. Subject and investigator satisfaction was very high. CONCLUSION: M89 significantly improves skin signs and symptoms after 4 weeks of continued use with no tolerance issues in subjects with dermatological indications. Moreover, subjects who have had recently undergone esthetic procedures M89 allowed a satisfying skin recovery.
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$a Spada, Julieta $u Clínica Dra Julieta Spada. Dermatología y Estética, Buenos Aires, Argentina.
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$a Kerscher, Martina $u Division of Cosmetic Science, University of Hamburg, Hamburg, Germany.
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$a Anfilova, Maryna $u Department of Dermatology and Venereology, Vinnytsya National Pirogov Memorial Medical University, Vinnytsya, Ukraine.
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$a Abdulla, Sonya $u Dermatology on Bloor, Toronto, ON, Canada.
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$a Preisz, Klaudia $u Buda Health Centre, Budapest, Hungary.
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$a Altmayer, Anita $u Department of Dermatology and Allergology, Szent-Györgyi Albert Clinical Centre, Szeged, Hungary.
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$a Delva, Catherine $u SyliaStat Lancrenon, Bourg-la-Reine, France.
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$a Kerob, Delphine $u Laboratoires Vichy International, Lavallois Perret, France.
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$a Arenbergerová, Monika $u Department of Dermato-venereology, Third Faculty of Medicine, Charles University, Královské Vinohrady University Hospital, Prague, Czech Republic.
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$a Tuz, Svyatoslav $u Sharapova Clinic, Samara, Russia.
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$a Araviiskaia, Elena $u Department of Dermatology, First Pavlov State Medical, University of St. Petersburg, St. Petersburg, Russia.
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