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Perfect date-the review of current research into molecular bases of mammalian fertilization
Z. Trebichalská, Z. Holubcová,
Language English Country Netherlands
Document type Journal Article, Review
Grant support
19-14990Y
Grantová Agentura České Republiky
Medicine 2017
Neuron Fund for Support of Science
NLK
Free Medical Journals
from 2008 to 1 year ago
PubMed Central
from 1997 to 1 year ago
Europe PubMed Central
from 1997 to 1 year ago
ProQuest Central
from 1999-01-01 to 1 year ago
Medline Complete (EBSCOhost)
from 2011-01-01 to 1 year ago
Health & Medicine (ProQuest)
from 1999-01-01 to 1 year ago
Public Health Database (ProQuest)
from 1999-01-01 to 1 year ago
- MeSH
- Reproductive Techniques, Assisted trends MeSH
- Diploidy MeSH
- Embryonic Development genetics MeSH
- Fertilization in Vitro trends MeSH
- Humans MeSH
- Models, Animal MeSH
- Ovary growth & development MeSH
- Spermatozoa growth & development MeSH
- Animals MeSH
- Zygote growth & development MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Fertilization is a multistep process during which two terminally differentiated haploid cells, an egg and a sperm, combine to produce a totipotent diploid zygote. In the early 1950s, it became possible to fertilize mammalian eggs in vitro and study the sequence of cellular and molecular events leading to embryo development. Despite all the achievements of assisted reproduction in the last four decades, remarkably little is known about the molecular aspects of human conception. Current fertility research in animal models is casting more light on the complexity of the process all our lives start with. This review article provides an update on the investigation of mammalian fertilization and highlights the practical implications of scientific discoveries in the context of human reproduction and reproductive medicine.
References provided by Crossref.org
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- $a Fertilization is a multistep process during which two terminally differentiated haploid cells, an egg and a sperm, combine to produce a totipotent diploid zygote. In the early 1950s, it became possible to fertilize mammalian eggs in vitro and study the sequence of cellular and molecular events leading to embryo development. Despite all the achievements of assisted reproduction in the last four decades, remarkably little is known about the molecular aspects of human conception. Current fertility research in animal models is casting more light on the complexity of the process all our lives start with. This review article provides an update on the investigation of mammalian fertilization and highlights the practical implications of scientific discoveries in the context of human reproduction and reproductive medicine.
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