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Gut microbiota alterations by nutritional supplement imuregen

Klara Kubelkova, Ivan Rychlik, Magdalena Crhanova, Daniela Karasova, Dasa Slizova, Jitka Zakova, Lenka Luksikova, Ales Macela

. 2020 ; 89 (3) : 114-125. [pub] 20200904

Language English Country Czech Republic

Persistent link   https://www.medvik.cz/link/bmc21006204

The gut microbiota is one of the modulators influencing its host's development, metabolism, as well as immunological, psychological, and cognitive abilities. The gut microbiota consortium influences enteroendocrine regulation, neurohormonal regulation, as well as natural immune regulation. Disruptions occurring in life can lead to dysbiosis that in turn influences the host homeostasis and/or disease. Targeted modulation of microbiota composition thus appears to be an appropriate intervention strategy in cases of certain specific health problems. Here, we demonstrate that application of the nutritional supplement Imuregen, which is a natural immune booster, modulates the Bacteroidetes/Firmicutes ratio in favor of the Bacteroidetes genera and causes no pathological changes to intestinal epithelium.

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