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Deadly COVID-19 among the elderly: Innate immune memory helping those most in need

Y. Sohrabi, H. Reinecke, LAB. Joosten, MG. Netea

. 2021 ; 2 (4) : 378-383. [pub] 20210224

Language English Country United States

Document type News

Age is a key risk factor associated with the severity of symptoms caused by SARS-CoV-2, and there is an urgent need to reduce COVID-19 morbidity and mortality in elderly individuals. We discuss evidence suggesting that trained immunity elicited by BCG vaccination may improve immune responses and can serve as a strategy to combat COVID-19 in this population.

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$a Netea, Mihai G $u Department of Internal Medicine and Radboud Centre of Infectious Diseases (RCI), Radboud University Medical Centre, Nijmegen, the Netherlands ; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany
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