The main goal of our prospective randomized study was comparing compare the effectiveness of ventilation control method "Automatic proportional minute ventilation (APMV) "versus manually set pressure control ventilation modes in relationship to lung mechanics and gas exchange. 80 patients undergoing coronary artery bypass grafting (CABG) were randomized into 2 groups. 40 patients in the first group No.1 (APMV group) were ventilated with pressure control (PCV) or pressure support ventilation (PSV) mode with APMV control. The other 40 patients (control group No.2) were ventilated with synchronized intermittent mandatory ventilation (SIMV-p) or pressure control modes (PCV) without APMV. Ventilation control with APMV was able to maintain minute ventilation more precisely in comparison with manual control (p<0.01), similarly deviations of ETCO(2) were significantly lower (p<0.01). The number of manual corrections of ventilation settings was significantly lower when APMV was used (p<0.01). The differences in lung mechanics and hemodynamics were not statistically significant. Ventilation using APMV is more precise in maintaining minute ventilation and gas exchange compared with manual settings. It required less staff intervention, while respiratory system mechanics and hemodynamics are comparable. APMV showed as effective and safe method applicable on top of all pressure control ventilation modes.

Clinic of Anesthesiology and Intensive Medicine East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine Safarik University Kosice Slovak Republic

Clinic of Anesthesiology and Intensive Medicine Slovak Health University Derer´s Hospital Bratislava Slovakia

Clinic of cardiac surgery East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine Safarik University Kosice Slovak Republic

Clinic of Cardiology East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine Safarik University Kosice Slovak Republic

Department of Human Physiology Faculty of Medicine Safarik University Kosice Slovak Republic

Faculty of Social Sciences and Health Care University of Constantine Philosopher Nitra Slovak Republic

Literatura

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$a Čandík, Peter $7 xx0146250 $u Department of Human Physiology, Faculty of Medicine, Safarik University, Kosice, Slovak Republic

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$a Minute ventilation stabilization during all pressure-control / support mechanical ventilation modes / $c P. Candík, F. Depta, S. Imrecze, F. Sabol, A. Kolesar, M. Jankajova, M. Paulíny, J. Benova, K. Galková, V. Donic, P. Török

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$a The main goal of our prospective randomized study was comparing compare the effectiveness of ventilation control method "Automatic proportional minute ventilation (APMV) "versus manually set pressure control ventilation modes in relationship to lung mechanics and gas exchange. 80 patients undergoing coronary artery bypass grafting (CABG) were randomized into 2 groups. 40 patients in the first group No.1 (APMV group) were ventilated with pressure control (PCV) or pressure support ventilation (PSV) mode with APMV control. The other 40 patients (control group No.2) were ventilated with synchronized intermittent mandatory ventilation (SIMV-p) or pressure control modes (PCV) without APMV. Ventilation control with APMV was able to maintain minute ventilation more precisely in comparison with manual control (p<0.01), similarly deviations of ETCO(2) were significantly lower (p<0.01). The number of manual corrections of ventilation settings was significantly lower when APMV was used (p<0.01). The differences in lung mechanics and hemodynamics were not statistically significant. Ventilation using APMV is more precise in maintaining minute ventilation and gas exchange compared with manual settings. It required less staff intervention, while respiratory system mechanics and hemodynamics are comparable. APMV showed as effective and safe method applicable on top of all pressure control ventilation modes.

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$a Depta, Filip $7 xx0232413 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine Safarik University, Kosice, Slovak Republic

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$a Török, Pavol $7 xx0119602 $u Clinic of Anesthesiology and Intensive Medicine, East Slovakian Institute of Cardiovascular Diseases and Faculty of Medicine Safarik University, Kosice, Slovak Republic; Faculty of Social Sciences and Health Care, University of Constantine Philosopher, Nitra, Slovak Republic

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