-
Something wrong with this record ?
Porcine model for the study of sperm capacitation, fertilization and male fertility
M. Zigo, P. Maňásková-Postlerová, D. Zuidema, K. Kerns, V. Jonáková, L. Tůmová, F. Bubeníčková, P. Sutovsky
Language English Country Germany
Document type Journal Article, Review
Grant support
2015-67015-23231
National Institute of Food and Agriculture
2019-67012-29714
National Institute of Food and Agriculture
5 R01 HD084353-02
Foundation for the National Institutes of Health
Food for the 21st Century Program
University of Missouri
CZ.1.05/1.1.00/02.0109
European Regional Development Fund
GA-18-11275S
Grantová Agentura České Republiky
RVO: 86652036
Institute of Biotechnology, Czech Academy of Sciences
INTER-COST LTC 18059
Ministerstvo Školství, Mládeže a Tělovýchovy
CIGA20182006
Internal Grant Agency of the Czech University of Life Sciences Prague
NLK
ProQuest Central
from 2000-12-01 to 1 year ago
Medline Complete (EBSCOhost)
from 2000-01-01 to 1 year ago
Nursing & Allied Health Database (ProQuest)
from 2000-12-01 to 1 year ago
Health & Medicine (ProQuest)
from 2000-12-01 to 1 year ago
- MeSH
- Fertility physiology MeSH
- Fertilization physiology MeSH
- Sperm Capacitation physiology MeSH
- Humans MeSH
- Disease Models, Animal MeSH
- Swine MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Mammalian fertilization remains a poorly understood event with the vast majority of studies done in the mouse model. The purpose of this review is to revise the current knowledge about semen deposition, sperm transport, sperm capacitation, gamete interactions and early embryonic development with a focus on the porcine model as a relevant, alternative model organism to humans. The review provides a thorough overview of post-ejaculation events inside the sow's reproductive tract including comparisons with humans and implications for human fertilization and assisted reproductive therapy (ART). Porcine methodology for sperm handling, preservation, in vitro capacitation, oocyte in vitro maturation, in vitro fertilization and intra-cytoplasmic sperm injection that are routinely used in pig research laboratories can be successfully translated into ART to treat human infertility. Last, but not least, new knowledge about mitochondrial inheritance in the pig can provide an insight into human mitochondrial diseases and new knowledge on polyspermy defense mechanisms could contribute to the development of new male contraceptives.
Department of Obstetrics Gynecology and Women's Health University of Missouri Columbia MO 65211 USA
Division of Animal Sciences University of Missouri Columbia MO 65211 USA
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21012631
- 003
- CZ-PrNML
- 005
- 20210714131636.0
- 007
- ta
- 008
- 210420s2020 gw f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/s00441-020-03181-1 $2 doi
- 035 __
- $a (PubMed)32140927
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a gw
- 100 1_
- $a Zigo, Michal $u Division of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA. zigom@missouri.edu
- 245 10
- $a Porcine model for the study of sperm capacitation, fertilization and male fertility / $c M. Zigo, P. Maňásková-Postlerová, D. Zuidema, K. Kerns, V. Jonáková, L. Tůmová, F. Bubeníčková, P. Sutovsky
- 520 9_
- $a Mammalian fertilization remains a poorly understood event with the vast majority of studies done in the mouse model. The purpose of this review is to revise the current knowledge about semen deposition, sperm transport, sperm capacitation, gamete interactions and early embryonic development with a focus on the porcine model as a relevant, alternative model organism to humans. The review provides a thorough overview of post-ejaculation events inside the sow's reproductive tract including comparisons with humans and implications for human fertilization and assisted reproductive therapy (ART). Porcine methodology for sperm handling, preservation, in vitro capacitation, oocyte in vitro maturation, in vitro fertilization and intra-cytoplasmic sperm injection that are routinely used in pig research laboratories can be successfully translated into ART to treat human infertility. Last, but not least, new knowledge about mitochondrial inheritance in the pig can provide an insight into human mitochondrial diseases and new knowledge on polyspermy defense mechanisms could contribute to the development of new male contraceptives.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a modely nemocí na zvířatech $7 D004195
- 650 _2
- $a fertilita $x fyziologie $7 D005298
- 650 _2
- $a fertilizace $x fyziologie $7 D005306
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a kapacitace spermií $x fyziologie $7 D013075
- 650 _2
- $a prasata $7 D013552
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Maňásková-Postlerová, Pavla $u Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, 25250, Vestec, Czech Republic ; Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, 16521, Prague, Czech Republic
- 700 1_
- $a Zuidema, Dalen $u Division of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA
- 700 1_
- $a Kerns, Karl $u Division of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA
- 700 1_
- $a Jonáková, Věra $u Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, 25250, Vestec, Czech Republic
- 700 1_
- $a Tůmová, Lucie $u Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, 16521, Prague, Czech Republic
- 700 1_
- $a Bubeníčková, Filipa $u Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, 16521, Prague, Czech Republic
- 700 1_
- $a Sutovsky, Peter $u Division of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA ; Department of Obstetrics, Gynecology & Women's Health, University of Missouri, Columbia, MO, 65211, USA
- 773 0_
- $w MED00001069 $t Cell and tissue research $x 1432-0878 $g Roč. 380, č. 2 (2020), s. 237-262
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/32140927 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20210420 $b ABA008
- 991 __
- $a 20210714131634 $b ABA008
- 999 __
- $a ok $b bmc $g 1650904 $s 1133010
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2020 $b 380 $c 2 $d 237-262 $e 20200305 $i 1432-0878 $m Cell and tissue research $n Cell Tissue Res $x MED00001069
- GRA __
- $a 2015-67015-23231 $p National Institute of Food and Agriculture
- GRA __
- $a 2019-67012-29714 $p National Institute of Food and Agriculture
- GRA __
- $a 5 R01 HD084353-02 $p Foundation for the National Institutes of Health
- GRA __
- $a Food for the 21st Century Program $p University of Missouri
- GRA __
- $a CZ.1.05/1.1.00/02.0109 $p European Regional Development Fund
- GRA __
- $a GA-18-11275S $p Grantová Agentura České Republiky
- GRA __
- $a RVO: 86652036 $p Institute of Biotechnology, Czech Academy of Sciences
- GRA __
- $a INTER-COST LTC 18059 $p Ministerstvo Školství, Mládeže a Tělovýchovy
- GRA __
- $a CIGA20182006 $p Internal Grant Agency of the Czech University of Life Sciences Prague
- LZP __
- $a Pubmed-20210420
