-
Je něco špatně v tomto záznamu ?
Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy
M. Kojan, M. Gajdoš, P. Říha, I. Doležalová, Z. Řehák, I. Rektor
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
Grantová podpora
17-32292AZV
Ministerstvo Zdravotnictví Ceské Republiky
NLK
ProQuest Central
od 1999-07-01 do Před 1 rokem
Medline Complete (EBSCOhost)
od 2009-05-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 1999-07-01 do Před 1 rokem
Psychology Database (ProQuest)
od 1999-07-01 do Před 1 rokem
- MeSH
- dospělí MeSH
- epilepsie parciální * diagnostické zobrazování chirurgie MeSH
- fluorodeoxyglukosa F18 * MeSH
- lidé MeSH
- magnetická rezonanční tomografie MeSH
- mozkový krevní oběh MeSH
- pozitronová emisní tomografie MeSH
- spinové značení MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Arterial spin labeling (ASL) is an MRI technique measuring brain perfusion using magnetically labeled blood as a tracer. The clinical utility of ASL for presurgical evaluation in non-lesional epilepsy as compared with the quantitative analysis of interictal [18F] fluorodeoxyglucose PET (FDG-PET) was studied. In 10 patients (4 female; median age 29 years) who underwent a complete presurgical evaluation followed by surgical resection, the presurgical FDG-PET and ASL scans were compared with the resection masks using asymmetry index (AI) maps. The positive predictive value (PPV) and sensitivity (SEN), were calculated from the number of voxels inside the mask (true positive), and outside the mask (false positive). The comparison of the PPVs showed better PPV in 6 patients using ASL and in 2 patients with PET. SEN was better in 4 patients using ASL and in 5 patients with PET. According to the Wilcoxon signed rank test for PPV (p = 0.74) and for SEN (p = 0.43), these methods have similar predictive power. ASL is a useful method for presurgical evaluation in non-lesional epilepsy. The main benefits of ASL over PET are that it avoids radiation exposure for patients, and it offers lower costs, higher availability, and better time efficiency.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21018407
- 003
- CZ-PrNML
- 005
- 20210830100002.0
- 007
- ta
- 008
- 210728s2021 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/s10548-021-00833-5 $2 doi
- 035 __
- $a (PubMed)33783670
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Kojan, Martin $u Brno Epilepsy Center, Department of Neurology, St. Anne's University Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic $u CEITEC - Central European Institute of Technology, Neuroscience Center, Masaryk University, Brno, Czech Republic
- 245 10
- $a Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy / $c M. Kojan, M. Gajdoš, P. Říha, I. Doležalová, Z. Řehák, I. Rektor
- 520 9_
- $a Arterial spin labeling (ASL) is an MRI technique measuring brain perfusion using magnetically labeled blood as a tracer. The clinical utility of ASL for presurgical evaluation in non-lesional epilepsy as compared with the quantitative analysis of interictal [18F] fluorodeoxyglucose PET (FDG-PET) was studied. In 10 patients (4 female; median age 29 years) who underwent a complete presurgical evaluation followed by surgical resection, the presurgical FDG-PET and ASL scans were compared with the resection masks using asymmetry index (AI) maps. The positive predictive value (PPV) and sensitivity (SEN), were calculated from the number of voxels inside the mask (true positive), and outside the mask (false positive). The comparison of the PPVs showed better PPV in 6 patients using ASL and in 2 patients with PET. SEN was better in 4 patients using ASL and in 5 patients with PET. According to the Wilcoxon signed rank test for PPV (p = 0.74) and for SEN (p = 0.43), these methods have similar predictive power. ASL is a useful method for presurgical evaluation in non-lesional epilepsy. The main benefits of ASL over PET are that it avoids radiation exposure for patients, and it offers lower costs, higher availability, and better time efficiency.
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a mozkový krevní oběh $7 D002560
- 650 12
- $a epilepsie parciální $x diagnostické zobrazování $x chirurgie $7 D004828
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 12
- $a fluorodeoxyglukosa F18 $7 D019788
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a magnetická rezonanční tomografie $7 D008279
- 650 _2
- $a pozitronová emisní tomografie $7 D049268
- 650 _2
- $a spinové značení $7 D013113
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Gajdoš, Martin $u CEITEC - Central European Institute of Technology, Neuroscience Center, Masaryk University, Brno, Czech Republic
- 700 1_
- $a Říha, Pavel $u Brno Epilepsy Center, Department of Neurology, St. Anne's University Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic $u CEITEC - Central European Institute of Technology, Neuroscience Center, Masaryk University, Brno, Czech Republic
- 700 1_
- $a Doležalová, Irena $u Brno Epilepsy Center, Department of Neurology, St. Anne's University Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic
- 700 1_
- $a Řehák, Zdeněk $u Department of Nuclear Medicine, Masaryk Memorial Cancer Institute, Brno, Czech Republic
- 700 1_
- $a Rektor, Ivan $u Brno Epilepsy Center, Department of Neurology, St. Anne's University Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic. irektor@med.muni.cz $u CEITEC - Central European Institute of Technology, Neuroscience Center, Masaryk University, Brno, Czech Republic. irektor@med.muni.cz
- 773 0_
- $w MED00007561 $t Brain topography $x 1573-6792 $g Roč. 34, č. 4 (2021), s. 504-510
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/33783670 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20210728 $b ABA008
- 991 __
- $a 20210830100002 $b ABA008
- 999 __
- $a ok $b bmc $g 1689505 $s 1138851
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2021 $b 34 $c 4 $d 504-510 $e 20210330 $i 1573-6792 $m Brain topography $n Brain Topogr $x MED00007561
- GRA __
- $a 17-32292AZV $p Ministerstvo Zdravotnictví Ceské Republiky
- LZP __
- $a Pubmed-20210728
