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Common, intermediate and well-documented HLA alleles in world populations: CIWD version 3.0.0

CK. Hurley, J. Kempenich, K. Wadsworth, J. Sauter, JA. Hofmann, D. Schefzyk, AH. Schmidt, P. Galarza, MBR. Cardozo, M. Dudkiewicz, L. Houdova, P. Jindra, BS. Sorensen, L. Jagannathan, A. Mathur, T. Linjama, T. Torosian, R. Freudenberger, A....

. 2020 ; 95 (6) : 516-531. [pub] 20200131

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem, Research Support, U.S. Gov't, Non-P.H.S.

Perzistentní odkaz   https://www.medvik.cz/link/bmc21020493

A catalog of common, intermediate and well-documented (CIWD) HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, -DQB1 and -DPB1 alleles has been compiled from over 8 million individuals using data from 20 unrelated hematopoietic stem cell volunteer donor registries. Individuals are divided into seven geographic/ancestral/ethnic groups and data are summarized for each group and for the total population. P (two-field) and G group assignments are divided into one of four frequency categories: common (≥1 in 10 000), intermediate (≥1 in 100 000), well-documented (≥5 occurrences) or not-CIWD. Overall 26% of alleles in IPD-IMGT/HLA version 3.31.0 at P group resolution fall into the three CIWD categories. The two-field catalog includes 18% (n = 545) common, 17% (n = 513) intermediate, and 65% (n = 1997) well-documented alleles. Full-field allele frequency data are provided but are limited in value by the variations in resolution used by the registries. A recommended CIWD list is based on the most frequent category in the total or any of the seven geographic/ancestral/ethnic groups. Data are also provided so users can compile a catalog specific to the population groups that they serve. Comparisons are made to three previous CWD reports representing more limited population groups. This catalog, CIWD version 3.0.0, is a step closer to the collection of global HLA frequencies and to a clearer view of HLA diversity in the human population as a whole.

Argentine HSC Donors Registry Buenos Aires Argentina

Bangalore Medical Services Trust Bangalore India

Central Unrelated Potential Bone Marrow Donor and Cord Blood Registry POLTRANSPLANT Warsaw Poland

Czech National Marrow Donors Registry and University Hospital Pilsen Pilsen Czech Republic

Danish Stem Cell Donors West Aarhus University Hospital Aarhus Denmark

DATRI Blood Stem Cell Donor Registry Chennai India

Department of Oncology Georgetown University Washington District of Columbia

DKMS BMST Foundation India Bangalore India

DKMS Tübingen Germany

Finnish Stem Cell Registry Helsinki Finland

Fundacja DKMS Warsaw Poland

Gift of Life Marrow Registry Florida

Hellenic Transplant Organization Athens Greece

Israel Ezer Mizion Bone Marrow Donor Registry Bnei Brak Israel

Italian Bone Marrow Donor Registry Genoa Italy

Kuwait National Stem Cell Registry Jabriya Kuwait

National Marrow Donor Program Minneapolis Minnesota

New Zealand Blood Service Auckland New Zealand

New Zealand Bone Marrow Donor Registry Auckland New Zealand

Norwegian Bone Marrow Donor Registry Oslo Norway

Saudi Stem Cell Donor Registry King Abdullah International Medical Research Center King Saud bin Abdulaziz University for Health Sciences King Abdulaziz Medical City Riyadh Ministry of National Guard Health Affairs Riyadh Saudi Arabia

Swiss Blood Stem Cells Bern Switzerland

Thai National Stem Cell Donor Registry Bangkok Thailand

The Bone Marrow Donor Programme Singapore

Tobias Registry of Swedish Bone Marrow Donors and Department of Immunology Genetics and Pathology Uppsala University Uppsala Sweden

University of West Bohemia New Technologies for the Information Society Pilsen Czech Republic

Citace poskytuje Crossref.org

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