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Pregnancy and Cancer: the INCIP Project

C. Maggen, VERA. Wolters, E. Cardonick, M. Fumagalli, MJ. Halaska, CAR. Lok, J. de Haan, K. Van Tornout, K. Van Calsteren, F. Amant, International Network on Cancer, Infertility and Pregnancy (INCIP)

. 2020 ; 22 (2) : 17. [pub] 20200205

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc21020753
E-zdroje Online Plný text

NLK ProQuest Central od 2013-01-01 do Před 1 rokem
Medline Complete (EBSCOhost) od 1999-01-01 do Před 1 rokem
Health & Medicine (ProQuest) od 2013-01-01 do Před 1 rokem

PURPOSE OF REVIEW: Cancer diagnosis in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to build on clinical recommendations based on worldwide collaborative research. RECENT FINDINGS: A pregnancy may complicate diagnostic and therapeutic oncological options, as the unborn child must be protected from potentially hazardous exposures. Pregnant patients should as much as possible be treated as non-pregnant patients, in order to preserve maternal prognosis. Some approaches need adaptations when compared with standard treatment for fetal reasons. Depending on the gestational age, surgery, radiotherapy, and chemotherapy are possible during pregnancy. A multidisciplinary approach is the best guarantee for experience-driven decisions. A setting with a high-risk obstetrical unit is strongly advised to safeguard fetal growth and health. Research wise, the INCIP invests in clinical follow-up of children, as cardiac function, neurodevelopment, cancer occurrence, and fertility theoretically may be affected. Furthermore, parental psychological coping strategies, (epi)genetic alterations, and pathophysiological placental changes secondary to cancer (treatment) are topics of ongoing research. Further international research is needed to provide patients diagnosed with cancer during pregnancy with the best individualized management plan to optimize obstetrical and oncological care.

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