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Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation
B. Lipový, F. Raška, I. Kocmanová, M. Hanslianová, M. Hladík, J. Holoubek, M. Bezdíček, C. Macháček
Jazyk angličtina Země Švýcarsko
Typ dokumentu kazuistiky
Grantová podpora
17-29874A
Ministerstvo Zdravotnictví Ceské Republiky
NV19-05-00214
Ministerstvo Zdravotnictví Ceské Republiky
NV17-29874A
MZ0
CEP - Centrální evidence projektů
Digitální knihovna NLK
Plný text - Článek
NLK
Directory of Open Access Journals
od 2015
PubMed Central
od 2015
Europe PubMed Central
od 2015
ProQuest Central
od 2015-06-01
Open Access Digital Library
od 2015-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2015
PubMed
34207136
DOI
10.3390/jof7060487
Knihovny.cz E-zdroje
- Publikační typ
- kazuistiky MeSH
Infectious complications are responsible for the majority of mortalities and morbidities of patients with critical burns. Although bacteria are the predominant etiological agents in such patients, yeasts and fungi have become relatively common causes of infections over the last decade. Here, we report a case of a young man with critical burns on 88% TBSA (total body surface area) arising as a part of polytrauma. The patient's history of orthotopic liver transplantation associated with the patient's need to use combined immunosuppressant therapy was an additional complication. Due to deep burns in the forearm region, we have (after a suitable wound bed preparation) applied a new bi-layered dermal substitute. The patient, however, developed a combined fungal infection in the region of this dermal substitute caused by Trichoderma longibrachiatum and Aspergillus fischeri (the first case ever reported). The infection caused the loss of the split-thickness skin grafts (STSGs); we had to perform repeated hydrosurgical and mechanical debridement and a systemic antifungal treatment prior to re-application of the STSGs. The subsequent skin transplant was successful.
Department of Clinical Microbiology University Hospital Brno 625 00 Brno Czech Republic
Department of Clinical Microbiology Vyškov Hospital 628 01 Vyškov Czech Republic
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