Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Cross-Species Comparisons of Nanoparticle Interactions with Innate Immune Systems: A Methodological Review

BJ. Swartzwelter, C. Mayall, A. Alijagic, F. Barbero, E. Ferrari, S. Hernadi, S. Michelini, NI. Navarro Pacheco, A. Prinelli, E. Swart, M. Auguste

. 2021 ; 11 (6) : . [pub] 20210609

Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc21024592

Grantová podpora
671881 Horizon 2020

Many components of the innate immune system are evolutionarily conserved and shared across many living organisms, from plants and invertebrates to humans. Therefore, these shared features can allow the comparative study of potentially dangerous substances, such as engineered nanoparticles (NPs). However, differences of methodology and procedure between diverse species and models make comparison of innate immune responses to NPs between organisms difficult in many cases. To this aim, this review provides an overview of suitable methods and assays that can be used to measure NP immune interactions across species in a multidisciplinary approach. The first part of this review describes the main innate immune defense characteristics of the selected models that can be associated to NPs exposure. In the second part, the different modes of exposure to NPs across models (considering isolated cells or whole organisms) and the main endpoints measured are discussed. In this synergistic perspective, we provide an overview of the current state of important cross-disciplinary immunological models to study NP-immune interactions and identify future research needs. As such, this paper could be used as a methodological reference point for future nano-immunosafety studies.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21024592
003      
CZ-PrNML
005      
20211013133851.0
007      
ta
008      
211006s2021 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/nano11061528 $2 doi
035    __
$a (PubMed)34207693
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Swartzwelter, Benjamin J $u Institute of Biochemistry and Cell Biology, National Research Council, 80131 Napoli, Italy
245    10
$a Cross-Species Comparisons of Nanoparticle Interactions with Innate Immune Systems: A Methodological Review / $c BJ. Swartzwelter, C. Mayall, A. Alijagic, F. Barbero, E. Ferrari, S. Hernadi, S. Michelini, NI. Navarro Pacheco, A. Prinelli, E. Swart, M. Auguste
520    9_
$a Many components of the innate immune system are evolutionarily conserved and shared across many living organisms, from plants and invertebrates to humans. Therefore, these shared features can allow the comparative study of potentially dangerous substances, such as engineered nanoparticles (NPs). However, differences of methodology and procedure between diverse species and models make comparison of innate immune responses to NPs between organisms difficult in many cases. To this aim, this review provides an overview of suitable methods and assays that can be used to measure NP immune interactions across species in a multidisciplinary approach. The first part of this review describes the main innate immune defense characteristics of the selected models that can be associated to NPs exposure. In the second part, the different modes of exposure to NPs across models (considering isolated cells or whole organisms) and the main endpoints measured are discussed. In this synergistic perspective, we provide an overview of the current state of important cross-disciplinary immunological models to study NP-immune interactions and identify future research needs. As such, this paper could be used as a methodological reference point for future nano-immunosafety studies.
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Mayall, Craig $u Department of Biology, Biotechnical Faculty, University of Liubljana, 1000 Ljubljana, Slovenia
700    1_
$a Alijagic, Andi $u Institute for Biomedical Research and Innovation, National Research Council, 90146 Palermo, Italy
700    1_
$a Barbero, Francesco $u Institut Català de Nanosciència i Nanotecnologia (ICN2), Bellaterra, 08193 Barcelona, Spain
700    1_
$a Ferrari, Eleonora $u Center for Plant Molecular Biology-ZMBP Eberhard-Karls University Tübingen, 72076 Tübingen, Germany
700    1_
$a Hernadi, Szabolcs $u School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK
700    1_
$a Michelini, Sara $u Department of Biosciences, Paris-Lodron University Salzburg, 5020 Salzburg, Austria
700    1_
$a Navarro Pacheco, Natividad Isabel $u Institute of Microbiology of the Czech Academy of Sciences, 142 20 Prague, Czech Republic
700    1_
$a Prinelli, Alessandra $u AvantiCell Science, Ltd., Ayr KA6 5HW, UK
700    1_
$a Swart, Elmer $u UK Centre for Ecology and Hydrology, Wallingford OX10 8BB, UK
700    1_
$a Auguste, Manon $u Department of Earth Environment and Life Sciences, University of Genova, 16126 Genova, Italy
773    0_
$w MED00193495 $t Nanomaterials (Basel, Switzerland) $x 2079-4991 $g Roč. 11, č. 6 (2021)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/34207693 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20211006 $b ABA008
991    __
$a 20211013133848 $b ABA008
999    __
$a ind $b bmc $g 1708387 $s 1145089
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 11 $c 6 $e 20210609 $i 2079-4991 $m Nanomaterials $n Nanomaterials (Basel) $x MED00193495
GRA    __
$a 671881 $p Horizon 2020
LZP    __
$a Pubmed-20211006

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace