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Effect of Treatment on Damage and Hospitalization in Elderly Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis

M. Weiner, SM. Goh, AJ. Mohammad, Z. Hrušková, A. Tanna, P. Sharp, A. Kang, A. Bruchfeld, D. Selga, Z. Chocová, K. Westman, P. Eriksson, L. Harper, CD. Pusey, V. Tesař, AD. Salama, M. Segelmark

Weiner, Maria
Author Weiner, Maria From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore. maria.weiner@liu.se M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University. maria.weiner@liu.se
Goh, Su Mein
Author Goh, Su Mein From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Mohammad, Aladdin J
Author Mohammad, Aladdin J From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Hrušková, Zdenka
Author Hrušková, Zdenka From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Tanna, Anisha
Author Tanna, Anisha From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Sharp, Phoebe
Author Sharp, Phoebe From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Kang, Amy
Author Kang, Amy From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Bruchfeld, Annette
Author Bruchfeld, Annette From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Selga, Daina
Author Selga, Daina From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Chocová, Zdeňka
Author Chocová, Zdeňka From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Westman, Kerstin
Author Westman, Kerstin From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Eriksson, Per
Author Eriksson, Per From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Harper, Lorraine
Author Harper, Lorraine From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Pusey, Charles D
Author Pusey, Charles D From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Tesař, Vladimír
Author Tesař, Vladimír From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Salama, Alan D
Author Salama, Alan D From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University
Segelmark, Mårten
Author Segelmark, Mårten From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö University College London Centre for Nephrology, Royal Free Hospital Department of Medicine, Imperial College London, London Institute of Clinical Sciences, University of Birmingham, Birmingham Department of Medicine, University of Cambridge, Cambridge, UK Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic Department of Renal Medicine, Tan Tock Seng Hospital, Singapore M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A. Tanna, MD, Department of Medicine, Imperial College London P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham A. Kang, MBBS, Department of Medicine, Imperial College London A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

Journal of rheumatology. 2020 ; 47 (4) : 580-588. [pub] 20190715

J Rheumatol
ISSN 0315-162X
Medvik
Source

Language English Country Canada

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link https://www.medvik.cz/link/bmc21026740

PubMed 31308208
DOI 10.3899/jrheum.190019
Knihovny.cz E-resources

MeSH
Granulomatosis with Polyangiitis * complications drug therapy MeSH
Hospitalization MeSH
Humans MeSH
Microscopic Polyangiitis * drug therapy MeSH
Peroxidase MeSH
Antibodies, Antineutrophil Cytoplasmic MeSH
Aged MeSH
Check Tag
Humans MeSH
Aged MeSH
Publication type
Journal Article MeSH
Research Support, Non-U.S. Gov't MeSH

OBJECTIVE: Age is a risk factor for organ damage, adverse events, and mortality in microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). However, the relationship between treatment and damage, hospitalizations, and causes of death in elderly patients is largely unknown. METHODS: Consecutive patients from Sweden, the United Kingdom, and the Czech Republic diagnosed between 1997 and 2013 were included. Inclusion criteria were a diagnosis of MPA or GPA and age 75 years or more at diagnosis. Treatment with cyclophosphamide (CYC), rituximab (RTX), and corticosteroids the first 3 months was registered. Outcomes up to 2 years from diagnosis included Vasculitis Damage Index (VDI), hospitalization, and cause of death. RESULTS: Treatment data were available for 167 of 202 patients. At 2 years, 4% had no items of damage. There was a positive association between VDI score at 2 years and Birmingham Vasculitis Activity Score at onset, and a negative association with treatment using CYC or RTX. Intravenous methylprednisolone dose was associated with treatment-related damage. During the first year, 69% of patients were readmitted to hospital. Myeloperoxidase-antineutrophil cytoplasmic antibody positivity and lower creatinine levels decreased the odds of readmission. The most common cause of death was infection, and this was associated with cumulative oral prednisolone dose. CONCLUSION: Immunosuppressive treatment with CYC or RTX in elderly patients with MPA and GPA was associated with development of less permanent organ damage and was not associated with hospitalization. However, higher doses of corticosteroids during the first 3 months was associated with treatment-related damage and fatal infections.

5 Tesař MD PhD Department of Nephrology 1st Faculty of Medicine Charles University and General University Hospital

A Bruchfeld MD PhD Department of Renal Medicine Karolinska University Hospital and CLINTEC Karolinska Institute

A D Salama MBBS FRCP PhD University College London Centre for Nephrology Royal Free Hospital

A J Mohammad MD PhD Department of Clinical Sciences Section of Rheumatology Lund University and Department of Medicine University of Cambridge

A Kang MBBS Department of Medicine Imperial College London

A Tanna MD Department of Medicine Imperial College London

C D Pusey DSc FMedSci Department of Medicine Imperial College London

D Selga MD PhD Department of Nephrology Lund University Skåne University Hospital

Department of Clinical Sciences Section of Rheumatology Lund University Lund

Department of Medicine Imperial College London London

Department of Medicine University of Cambridge Cambridge UK

Department of Nephrology 1st Faculty of Medicine Charles University and General University Hospital Prague Czech Republic

Department of Nephrology Lund University Skåne University Hospital Lund and Malmö

Department of Renal Medicine Karolinska University Hospital and CLINTEC Karolinska Institute Stockholm

Department of Renal Medicine Tan Tock Seng Hospital Singapore

From the Department of Nephrology and Department of Medical and Health Sciences Department of Rheumatology and Department of Clinical and Experimental Medicine Linköping University Linköping

Institute of Clinical Sciences University of Birmingham Birmingham

K Westman MD PhD Department of Nephrology Lund University Skåne University Hospital

L Harper MBChB PhD Institute of Clinical Sciences University of Birmingham

M Segelmark MD PhD Department of Nephrology and Department of Medical and Health Sciences Linköping University

M Weiner MD Department of Nephrology and Department of Medical and Health Sciences Linköping University

P Eriksson MD PhD Department of Rheumatology and Department of Clinical and Experimental Medicine Linköping University

P Sharp PhD Institute of Clinical Sciences University of Birmingham

S M Goh MBBS University College London Centre for Nephrology Royal Free Hospital and Department of Renal Medicine Tan Tock Seng Hospital

University College London Centre for Nephrology Royal Free Hospital

Z Chocová MD Department of Nephrology 1st Faculty of Medicine Charles University and General University Hospital

Z Hrušková MD PhD Department of Nephrology 1st Faculty of Medicine Charles University and General University Hospital

References provided by Crossref.org

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100 1_: $a Weiner, Maria $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore. maria.weiner@liu.se $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University. maria.weiner@liu.se

245 10: $a Effect of Treatment on Damage and Hospitalization in Elderly Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis / $c M. Weiner, SM. Goh, AJ. Mohammad, Z. Hrušková, A. Tanna, P. Sharp, A. Kang, A. Bruchfeld, D. Selga, Z. Chocová, K. Westman, P. Eriksson, L. Harper, CD. Pusey, V. Tesař, AD. Salama, M. Segelmark

520 9_: $a OBJECTIVE: Age is a risk factor for organ damage, adverse events, and mortality in microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). However, the relationship between treatment and damage, hospitalizations, and causes of death in elderly patients is largely unknown. METHODS: Consecutive patients from Sweden, the United Kingdom, and the Czech Republic diagnosed between 1997 and 2013 were included. Inclusion criteria were a diagnosis of MPA or GPA and age 75 years or more at diagnosis. Treatment with cyclophosphamide (CYC), rituximab (RTX), and corticosteroids the first 3 months was registered. Outcomes up to 2 years from diagnosis included Vasculitis Damage Index (VDI), hospitalization, and cause of death. RESULTS: Treatment data were available for 167 of 202 patients. At 2 years, 4% had no items of damage. There was a positive association between VDI score at 2 years and Birmingham Vasculitis Activity Score at onset, and a negative association with treatment using CYC or RTX. Intravenous methylprednisolone dose was associated with treatment-related damage. During the first year, 69% of patients were readmitted to hospital. Myeloperoxidase-antineutrophil cytoplasmic antibody positivity and lower creatinine levels decreased the odds of readmission. The most common cause of death was infection, and this was associated with cumulative oral prednisolone dose. CONCLUSION: Immunosuppressive treatment with CYC or RTX in elderly patients with MPA and GPA was associated with development of less permanent organ damage and was not associated with hospitalization. However, higher doses of corticosteroids during the first 3 months was associated with treatment-related damage and fatal infections.

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700 1_: $a Goh, Su Mein $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Mohammad, Aladdin J $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Hrušková, Zdenka $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Tanna, Anisha $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Sharp, Phoebe $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Kang, Amy $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Bruchfeld, Annette $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Selga, Daina $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Chocová, Zdeňka $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Westman, Kerstin $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Eriksson, Per $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Harper, Lorraine $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Pusey, Charles D $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Tesař, Vladimír $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Salama, Alan D $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

700 1_: $a Segelmark, Mårten $u From the Department of Nephrology and Department of Medical and Health Sciences, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund; Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute, Stockholm; Department of Nephrology, Lund University, Skåne University Hospital, Lund and Malmö; University College London Centre for Nephrology, Royal Free Hospital; Department of Medicine, Imperial College London, London; Institute of Clinical Sciences, University of Birmingham, Birmingham; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic; Department of Renal Medicine, Tan Tock Seng Hospital, Singapore $u M. Weiner, MD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University; S.M. Goh, MBBS, University College London Centre for Nephrology, Royal Free Hospital, and Department of Renal Medicine, Tan Tock Seng Hospital; A.J. Mohammad, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Department of Medicine, University of Cambridge; Z. Hrušková, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A. Tanna, MD, Department of Medicine, Imperial College London; P. Sharp, PhD, Institute of Clinical Sciences, University of Birmingham; A. Kang, MBBS, Department of Medicine, Imperial College London; A. Bruchfeld, MD, PhD, Department of Renal Medicine, Karolinska University Hospital and CLINTEC Karolinska Institute; D. Selga, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; Z. Chocová, MD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; K. Westman, MD, PhD, Department of Nephrology, Lund University, Skåne University Hospital; P. Eriksson, MD, PhD, Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University; L. Harper, MBChB, PhD, Institute of Clinical Sciences, University of Birmingham; C.D. Pusey, DSc, FMedSci, Department of Medicine, Imperial College London; V. Tesař, MD, PhD, Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital; A.D. Salama, MBBS, FRCP, PhD, University College London Centre for Nephrology, Royal Free Hospital; M. Segelmark, MD, PhD, Department of Nephrology and Department of Medical and Health Sciences, Linköping University

773 0_: $w MED00002935 $t The Journal of rheumatology $x 0315-162X $g Roč. 47, č. 4 (2020), s. 580-588

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