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Long-Term Effect of Exercise on Irisin Blood Levels-Systematic Review and Meta-Analysis
T. Jandova, A. Buendía-Romero, H. Polanska, V. Hola, M. Rihova, T. Vetrovsky, J. Courel-Ibáñez, M. Steffl
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, přehledy
Free Medical Journals od 2013
PubMed Central od 2013
Europe PubMed Central od 2013
ProQuest Central od 2013-01-01
Open Access Digital Library od 2013-01-01
Open Access Digital Library od 2013-01-01
Nursing & Allied Health Database (ProQuest) od 2013-01-01
Public Health Database (ProQuest) od 2013-01-01
ROAD: Directory of Open Access Scholarly Resources od 2013
Odkazy
PubMed
34828485
DOI
10.3390/healthcare9111438
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Physical exercise may activate a number of important biochemical processes in the human body. The aim of this systematic review and meta-analysis was to identify the long-term effect of physical activity on irisin blood levels. We searched PubMed, Scopus, and Web of Science for articles addressing the long-term effect of physical exercise on irisin blood levels. Fifty-nine articles were included in the final qualitative and quantitative syntheses. A statistically significant within-group effect of exercise on irisin blood levels was in 33 studies; out of them, the irisin level increased 23× and decreased 10×. The significant positive between-groups effect was found 11×. Furthermore, the meta-analysis indicated that physical exercise had a significant positive effect on irisin blood levels (SMD = 0.39 (95% CI 0.27-0.52)). Nevertheless, considerably high heterogeneity was found in all the analyses. This systematic review and meta-analysis indicate that physical exercise might increase irisin blood levels; however, the results of individual studies were considerably inconsistent, which questions the methodological detection of irisin by ELISA kits.
Faculty of Physical Education and Sport Charles University 16252 Prague Czech Republic
Faculty of Sport Sciences University of Murcia 30720 Murcia Spain
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