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Lifetime Carcinogenic Risk Proportions from Inhalation Exposures in Industrial and Non-Industrial Regions
V. Jiřík, L. Tomášek, I. Fojtíková, T. Janoš, M. Stanovská, P. Guňková, A. Dalecká, A. Vrtková, RJ. Šrám
Language English Country Switzerland
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
Free Medical Journals
from 2004
PubMed Central
from 2005
Europe PubMed Central
from 2005
ProQuest Central
from 2009-01-01
Open Access Digital Library
from 2004-01-01
Open Access Digital Library
from 2005-01-01
Medline Complete (EBSCOhost)
from 2008-12-01
Health & Medicine (ProQuest)
from 2009-01-01
Public Health Database (ProQuest)
from 2009-01-01
ROAD: Directory of Open Access Scholarly Resources
from 2004
- MeSH
- Risk Assessment MeSH
- Inhalation Exposure * statistics & numerical data MeSH
- Carcinogens MeSH
- Humans MeSH
- Dust MeSH
- Occupational Exposure * statistics & numerical data MeSH
- Industry MeSH
- Cross-Sectional Studies MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
The aim of this work was to estimate the share of selected significant risk factors for respiratory cancer in the overall incidence of this disease and their comparison in two environmentally different burdened regions. A combination of a longitudinal cross-sectional population study with a US EPA health risk assessment methodology was used. The result of this procedure is the expression of lifelong carcinogenic risks and their contribution in the overall incidence of the disease. Compared to exposures to benzo[a]pyrene in the air and fibrogenic dust in the working air, several orders of magnitude higher share of the total incidence of respiratory cancer was found in radon exposures, for women 60% in the industrial area, respectively 100% in the non-industrial area, for men 24%, respectively 15%. The share of risks in workers exposed to fibrogenic dust was found to be 0.35% in the industrial area. For benzo[a]pyrene, the share of risks was below 1% and the share of other risk factors was in the monitored areas was up to 85%. The most significant share in the development of respiratory cancer in both monitored areas is represented by radon for women and other risk factors for men.
References provided by Crossref.org
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