Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Expert Panel Guidance and Narrative Review of Treatment Simplification of Complex Insulin Regimens to Improve Outcomes in Type 2 Diabetes

EB. Jude, MT. Malecki, R. Gomez Huelgas, M. Prazny, F. Snoek, T. Tankova, D. Giugliano, K. Khunti

. 2022 ; 13 (4) : 619-634. [pub] 20220311

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc22009731

Given the progressive nature of type 2 diabetes (T2D), most individuals with the disease will ultimately undergo treatment intensification. This usually involves the stepwise addition of a new glucose-lowering agent or switching to a more complex insulin regimen. However, complex treatment regimens can result in an increased risk of hypoglycaemia and high treatment burden, which may impact negatively on both therapeutic adherence and overall quality of life. Individuals with good glycaemic control may also be overtreated with unnecessarily complex regimens. Treatment simplification aims to reduce individual treatment burden, without compromising therapeutic effectiveness or safety. Despite data showing that simplifying therapy can achieve good glycaemic control without negatively impacting on treatment efficacy or safety, it is not always implemented in clinical practice. Current clinical guidelines focus on treatment intensification, rather than simplification. Where simplification is recommended, clear guidance is lacking and mostly focused on treatment of the elderly. An expert, multidisciplinary panel evaluated the current treatment landscape with respect to guidance, published evidence, recommendations and approaches regarding simplification of complex insulin regimens. This article outlines the benefits of treatment simplification and provides practical recommendations on simplifying complex insulin treatment strategies in people with T2D using illustrative cases.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc22009731
003      
CZ-PrNML
005      
20220425131535.0
007      
ta
008      
220420s2022 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1007/s13300-022-01222-2 $2 doi
035    __
$a (PubMed)35274219
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Jude, Edward B $u Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, UK $u University of Manchester, Manchester, UK
245    10
$a Expert Panel Guidance and Narrative Review of Treatment Simplification of Complex Insulin Regimens to Improve Outcomes in Type 2 Diabetes / $c EB. Jude, MT. Malecki, R. Gomez Huelgas, M. Prazny, F. Snoek, T. Tankova, D. Giugliano, K. Khunti
520    9_
$a Given the progressive nature of type 2 diabetes (T2D), most individuals with the disease will ultimately undergo treatment intensification. This usually involves the stepwise addition of a new glucose-lowering agent or switching to a more complex insulin regimen. However, complex treatment regimens can result in an increased risk of hypoglycaemia and high treatment burden, which may impact negatively on both therapeutic adherence and overall quality of life. Individuals with good glycaemic control may also be overtreated with unnecessarily complex regimens. Treatment simplification aims to reduce individual treatment burden, without compromising therapeutic effectiveness or safety. Despite data showing that simplifying therapy can achieve good glycaemic control without negatively impacting on treatment efficacy or safety, it is not always implemented in clinical practice. Current clinical guidelines focus on treatment intensification, rather than simplification. Where simplification is recommended, clear guidance is lacking and mostly focused on treatment of the elderly. An expert, multidisciplinary panel evaluated the current treatment landscape with respect to guidance, published evidence, recommendations and approaches regarding simplification of complex insulin regimens. This article outlines the benefits of treatment simplification and provides practical recommendations on simplifying complex insulin treatment strategies in people with T2D using illustrative cases.
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Malecki, Maciej T $u Department of Metabolic Diseases, Jagiellonian University Medical College, Kraków, Poland
700    1_
$a Gomez Huelgas, Ricardo $u Internal Medicine Department, Regional University Hospital of Málaga, Málaga, Spain $u Instituto de Investigación Biomédica de Málaga (IBIMA), University of Málaga, Málaga, Spain $u CIBER Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain
700    1_
$a Prazny, Martin $u 3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
700    1_
$a Snoek, Frank $u Department of Medical Psychology, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, The Netherlands
700    1_
$a Tankova, Tsvetalina $u Department of Endocrinology, Medical University-Sofia, Sofia, Bulgaria
700    1_
$a Giugliano, Dario $u Division of Endocrinology and Metabolic Diseases, University Hospital, Università della Campania Luigi Vanvitelli, Naples, Italy
700    1_
$a Khunti, Kamlesh $u Diabetes Research Centre, University of Leicester, Leicester, UK. kk22@leicester.ac.uk $1 https://orcid.org/0000000323437099 $7 xx0258606
773    0_
$w MED00194311 $t Diabetes therapy : research, treatment and education of diabetes and related disorders $x 1869-6953 $g Roč. 13, č. 4 (2022), s. 619-634
856    41
$u https://pubmed.ncbi.nlm.nih.gov/35274219 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20220420 $b ABA008
991    __
$a 20220425131533 $b ABA008
999    __
$a ind $b bmc $g 1784375 $s 1160929
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2022 $b 13 $c 4 $d 619-634 $e 20220311 $i 1869-6953 $m Diabetes therapy $n Diabetes Ther $x MED00194311
LZP    __
$a Pubmed-20220420

Najít záznam

Citační ukazatele

Možnosti archivace