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Radical hysterectomy in early cervical cancer in Europe: characteristics, outcomes and evaluation of ESGO quality indicators
F. Boria, L. Chiva, V. Zanagnolo, D. Querleu, N. Martin-Calvo, ME. Căpîlna, A. Fagotti, A. Kucukmetin, C. Mom, G. Chakalova, A. Shamistan, M. Malzoni, F. Narducci, O. Arencibia, F. Raspagliesi, T. Toptas, D. Cibula, D. Kaidarova, MM. Meydanli, M....
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články
NLK
ProQuest Central
od 2018-01-01 do Před 6 měsíci
Health & Medicine (ProQuest)
od 2018-01-01 do Před 6 měsíci
PubMed
34321289
DOI
10.1136/ijgc-2021-002587
Knihovny.cz E-zdroje
- MeSH
- hysterektomie metody MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory děložního čípku chirurgie MeSH
- ukazatele kvality zdravotní péče normy MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Evropa MeSH
INTRODUCTION: Comprehensive updated information on cervical cancer surgical treatment in Europe is scarce. OBJECTIVE: To evaluate baseline characteristics of women with early cervical cancer and to analyze the outcomes of the ESGO quality indicators after radical hysterectomy in the SUCCOR database. METHODS: The SUCCOR database consisted of 1272 patients who underwent radical hysterectomy for stage IB1 cervical cancer (FIGO 2009) between January 2013 and December 2014. After exclusion criteria, the final sample included 1156 patients. This study first described the clinical, surgical, pathological, and follow-up variables of this population and then analyzed the outcomes (disease-free survival and overall survival) after radical hysterectomy. Surgical-related ESGO quality indicators were assessed and the accomplishment of the stated recommendations was verified. RESULTS: The mean age of the patients was 47.1 years (SD 10.8), with a mean body mass index of 25.4 kg/m2 (SD 4.9). A total of 423 (36.6%) patients had a previous cone biopsy. Tumor size (clinical examination) <2 cm was observed in 667 (57.7%) patients. The most frequent histology type was squamous carcinoma (794 (68.7%) patients), and positive lymph nodes were found in 143 (12.4%) patients. A total of 633 (54.8%) patients were operated by open abdominal surgery. Intra-operative complications occurred in 108 (9.3%) patients, and post-operative complications during the first month occurred in 249 (21.5%) patients, with bladder dysfunction as the most frequent event (119 (10.3%) patients). Clavien-Dindo grade III or higher complication occurred in 56 (4.8%) patients. A total of 510 (44.1%) patients received adjuvant therapy. After a median follow-up of 58 months (range 0-84), the 5-year disease-free survival was 88.3%, and the overall survival was 94.9%. In our population, 10 of the 11 surgical-related quality indicators currently recommended by ESGO were fully fulfilled 5 years before its implementation. CONCLUSIONS: In this European cohort, the rate of adjuvant therapy after radical hysterectomy is higher than for most similar patients reported in the literature. The majority of centers were already following the European recommendations even 5 years prior to the ESGO quality indicator implementations.
Amsterdam University Medical Centres Amsterdam Noord Holland Netherlands
Azienda Ospedaliero Universitaria di Bologna Policlinico SantOrsola Malpighi Bologna Italy
Bellvitge University Hospital L'Hospitalet de Llobregat Catalunya Spain
Clinic of Obstetrics and Gynecology Hospital San Gerardo Monza Italy
Clinica Universidad de Navarra Departamento de Ginecologia y Obstetricia Madrid Spain
Clinica Universidad de Navarra Departamento de Ginecologia y Obstetricia Pamplona Navarra Spain
Clinical Hospital Center Rijeka Rijeka Croatia
Clinical Hospital Center Zagreb Croatia
Department of Gynaecology LUMC Leiden Netherlands
Department of Gynecologíc Oncology Hospital Universitario La Paz Madrid Madrid Spain
Department of Gynecologic Oncology Universidad de Navarra Pamplona Navarra Spain
Department of Gynecological Oncology Radboudumc Nijmegen Netherlands
Department of Gynecology and Oncology Jagiellonian University Krakow Poland
Department of Gynecology Centre Oscar Lambret Lille France
Department of Gynecology Clinica Universitaria de Navarra Madrid Spain
Department of Gynecology Clinica Universitaria de Navarra Pamplona Navarra Spain
Department of Gynecology Instituto Português de Oncologia de Lisboa Lisboa Lisboa Portugal
Department of Medicine and Surgery University of Milan Bicocca Milano Italy
Department of Obstetrics and Gynecology Clinica Universidad de Navarra Madrid Spain
Department of Obstetrics and Gynecology School of Medicine
Department of Obstetrics and Gynecology Tampere University Hospital Tampere Finland
Department of Obstetrics and Gynecology University of Liege Liege Belgium
Department of Obstetrics and Gynecology University of Prague Prague Czech Republic
Department of Preventive Medicine and Public Health Universidad de Navarra Pamplona Spain
Department of Surgery Fondazione IRCCS Istituto Nazionale dei Tumori Milano Lombardia Italy
Department of Surgery Institut Bergonie Bordeaux France
Department of Surgery LISOD Israeli Oncological Hospital Kyiv region Ukraine
Emergency County Hospital Targu Mures Targu Mures Romania
General Hospital of Thessaloniki Papageorgiou Thessaloniki Central Macedonia Greece
Institut Curie Paris Île de France France
Instituto Português de Oncologia do Porto Francisco Gentil Porto Portugal
Istituto Europeo di Oncologia Milano Anognnn Italy
Kardinal Schwarzenberg'sches Krankenhaus Schwarzach Steiermark Austria
Lviv Oncology Center Lviv Ukraine
National Center of Oncology Baku Azerbaijan
North Estonia Medical Centre Tallinn Estonia
Oncogynecology Kazahskij Naucno Issledovatel'skij Institut Onkologii i Radiologii Almaty Kazakhstan
Queen Elizabeth Hospital Gateshead Gateshead UK
University Hospitals of Leicester NHS Trust Leicester Leicester UK
University Maternal Hospital Canary Islands Las Palma Spain
Citace poskytuje Crossref.org
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