This literature research had two main objectives. The first objective was to quantify how frequently artificial intelligence (AI) was utilized in dental literature from 2011 until 2021. The second objective was to distinguish the focus of such publications; in particular, dental field and topic. The main inclusion criterium was an original article or review in English focused on dental utilization of AI. All other types of publications or non-dental or non-AI-focused were excluded. The information sources were Web of Science, PubMed, Scopus, and Google Scholar, queried on 19 April 2022. The search string was "artificial intelligence" AND (dental OR dentistry OR tooth OR teeth OR dentofacial OR maxillofacial OR orofacial OR orthodontics OR endodontics OR periodontics OR prosthodontics). Following the removal of duplicates, all remaining publications were returned by searches and were screened by three independent operators to minimize the risk of bias. The analysis of 2011-2021 publications identified 4413 records, from which 1497 were finally selected and calculated according to the year of publication. The results confirmed a historically unprecedented boom in AI dental publications, with an average increase of 21.6% per year over the last decade and a 34.9% increase per year over the last 5 years. In the achievement of the second objective, qualitative assessment of dental AI publications since 2021 identified 1717 records, with 497 papers finally selected. The results of this assessment indicated the relative proportions of focal topics, as follows: radiology 26.36%, orthodontics 18.31%, general scope 17.10%, restorative 12.09%, surgery 11.87% and education 5.63%. The review confirms that the current use of artificial intelligence in dentistry is concentrated mainly around the evaluation of digital diagnostic methods, especially radiology; however, its implementation is expected to gradually penetrate all parts of the profession.

Department of Genetics Cancer Research Institute Biomedical Research Center Slovak Academy of Sciences Dubravska Cesta 9 84505 Bratislava Slovakia

Department of Histology and Embryology Faculty of Medicine Comenius University in Bratislava 81372 Bratislava Slovakia

Department of Oral and Maxillofacial Surgery Faculty of Medicine Comenius University in Bratislava and University Hospital 81372 Bratislava Slovakia

Department of Orthodontics and Cleft Anomalies Faculty Hospital Kralovske Vinohrady Dental Clinic 3rd Medical Faculty Charles University 10034 Prague Czech Republic

Department of Simulation and Virtual Medical Education Faculty of Medicine Comenius University in Bratislava Sasinkova 4 81272 Bratislava Slovakia

Department of Stomatology and Maxillofacial Surgery Faculty of Medicine Comenius University in Bratislava 81250 Bratislava Slovakia

Department of Stomatology and Maxillofacial Surgery Jessenius Faculty of Medicine in Martin Comenius University Bratislava Kollárova 2 03659 Martin Slovakia

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