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Allergies and COVID-19 vaccines: An ENDA/EAACI Position paper
A. Barbaud, LH. Garvey, A. Arcolaci, K. Brockow, F. Mori, C. Mayorga, P. Bonadonna, M. Atanaskovic-Markovic, L. Moral, G. Zanoni, M. Pagani, A. Soria, M. Jošt, JC. Caubet, A. Carmo, AA. Mona, A. Alvarez-Perea, S. Bavbek, B. Benedetta, MB. Bilo,...
Jazyk angličtina Země Dánsko
Typ dokumentu časopisecké články
PubMed
35112371
DOI
10.1111/all.15241
Knihovny.cz E-zdroje
- MeSH
- anafylaxe * diagnóza MeSH
- COVID-19 * prevence a kontrola MeSH
- léková alergie * diagnóza etiologie terapie MeSH
- lidé MeSH
- mRNA vakcíny MeSH
- syntetické vakcíny MeSH
- vakcíny proti COVID-19 * škodlivé účinky MeSH
- vakcíny * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management is not standardized. METHOD: Members of the European Network for Drug Allergy and the European Academy of Allergy and Clinical Immunology interested in drug allergy participated in an online questionnaire on pre-vaccination screening and management of allergic reactions to COVID-19 vaccines, and literature was analysed. RESULTS: No death due to anaphylaxis to COVID-19 vaccines has been confirmed in scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate and tromethamine are excipients. The authors propose allergy evaluation of persons with the following histories: 1-anaphylaxis to injectable drug or vaccine containing PEG or derivatives; 2-anaphylaxis to oral/topical PEG containing products; 3-recurrent anaphylaxis of unknown cause; 4-suspected or confirmed allergy to any mRNA vaccine; and 5-confirmed allergy to PEG or derivatives. We recommend a prick-to-prick skin test with the left-over solution in the suspected vaccine vial to avoid waste. Prick test panel should include PEG 4000 or 3500, PEG 2000 and polysorbate 80. The value of in vitro test is arguable. CONCLUSIONS: These recommendations will lead to a better knowledge of the management and mechanisms involved in anaphylaxis to COVID-19 vaccines and enable more people with history of allergy to be vaccinated.
Allergology and Clinical Immunology Department Centre Hospitalier Lyon Sud Pierre Bénite France
Allergy and Clinical Immunology Unit Centro Hospitalar E Universitário de Coimbra Coimbra Portugal
Allergy Clinic Copenhagen University Hospital at Gentofte Copenhagen Denmark
Allergy Department Centro Hospitalar Universitário do Porto Porto Portugal
Allergy Department Hospital General Universitario Gregorio Marañón Madrid Spain
Allergy Unit Angers University Hospital Angers France
Allergy Unit Department of Internal Medicine University Hospital Ospedali Riuniti di Ancona Italy
Allergy Unit Department of Pediatrics Meyer Children's University Hospital
Allergy Unit Fondazione Policlinico Gemelli IRCCS Largo Gemelli Rome Italy
Allergy Unit Regional University Hospital of Malaga IBIMA UMA ARADyAL Malaga Spain
Allergy Unit S S Filippo and Nicola Avezzano Italy
Allergy Unit Verona University Hospital Verona Italy
Barts Health NHS Trust St Bartholomew's Hospital London UK
Center for Rhinology and Allergology Wiesbaden Germany
Charité Universitätsmedizin Berlin Klinik für Dermatologie Berlin Germany
Department of Adult Allergy Memorial Ankara Hospital Ankara Turkey
Department of Clinical and Molecular Sciences Università Politecnica delle Marche Ancona Italy
Department of Clinical Immunology King's College Hospital London UK
Department of Clinical Medicine University of Copenhagen Denmark
Department of Dermatology and Allergy Cantonal Hospital Aarau Aarau Switzerland
Department of Dermatology Universitair Ziekenhuis Vrije Universiteit Brussel Brussel Belgium
Department of Dermatology Venerology and Allergology Universitätsmedizin Leipzig Leipzig Germany
Department of ENT AUMC Amsterdam The Netherlands
Department of Immunology and Allergy Medical University of Lodz Poland
Department of Medical Sciences Uppsala university Sweden
Department of Women Children Teenagers University Hospital of Geneva Geneva Switzerland
Faculty of Medicine Dpt of Pediatric Allergy and Immunology Mersin University Mersin Turkey
Faculty of Medicine Transylvania University Brasov Romania
Faculty of Medicine University of Belgrade University Children's Hospital Belgrade Serbia
Floridsdorf Allergy Center Vienna Austria
Gennet s r o Allergy and Clinical Immunology Czech Republic
Hospital Quironsalud Cordoba Cordoba Spain
Hospital Vito Fazzi Lecce Italy
Immunology Department Manchester University NHS Foundation Trust Manchester UK
Immunology Unit University Hospital of Verona Policlinico G B Rossi Verona Italy
Infanta Leonor University Hospital Madrid Spain
Institute of Immunology Faculty of Medicine University of Coimbra Coimbra Portugal
Medicine Department Medicine Ward Mantova Hospital ASST di Mantova Italy
Microbiology Department Faculty of Medicine Kuwait University Kuwait
National Heart and Lung Institute Imperial College London London UK
Oasi Research Institute IRCCS Troina Italy
Service transversal d'allergologie et immunologie clinique CHR de Tours Tours France
SOS Allergologia e Immunologia Azienda USL Toscana Centro Ospedale S Stefano Prato Italy
University Clinic Golnik Slovenia
University Clinic of Respiratory and Allergic Diseases Golnik Golnik Slovenia
Citace poskytuje Crossref.org
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