• Je něco špatně v tomto záznamu ?

Photobiomodulation Therapy After Mesiodens Surgery: Evaluation of Immunological Markers and Three-Dimensional X-Ray Analysis-Placebo-Controlled Study

E. Sediva, T. Dostalova, P. Urbanova, H. Eliasova, S. Podzimek, E. Misova

. 2022 ; 40 (7) : 472-479. [pub] 20220704

Jazyk angličtina Země Spojené státy americké

Typ dokumentu klinické zkoušky kontrolované, časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc22025362

Objective: Photobiomodulation therapy (PBMT) applies therapeutic lasers or light-emitting diodes radiation to the surface of the body. From the medical point of view, PBMT systems have been employed for reducing pain, inflammation, and edema, promoting healing of wounds, deeper tissues and nerves, preventing tissue damage, etc. Background data: PBMT or biostimulation has a wide range of applications in maxillofacial surgery. It is known that the therapy effect using three-dimensional (3D) image was not really clear during the healing process. Materials and methods: The treatment group comprised 38 patients, 18 of them were treated with laser radiation (diode laser 808 nm) and 20 patients presented the control group. The surgery plan was monitored using cone beam computed tomography, in particular the number, shape, and size of mesiodens were registered. The effectivity of laser therapy was assessed based on immunological tests-secretory immunoglobulin A (sIgA) and lysozyme levels measured in nonstimulated saliva before and after treatment. Results: For sIgA (both in millimeters and milligrams per liter), the measurements displayed differences between pre- and postsurgery values, the postsurgery values being significantly lower than the presurgery values. In addition, interaction with the laser treatment plan was found, meaning that the laser treatment affected the sIgA levels. The decrease in sIgA levels in the control group was statistically significant. However, there was no significant change in sIgA levels in the laser group. The lysozyme trends appeared to be identical to the sIgA levels, that is, rising in the laser group and decreasing in the control group. The initial values for each group, however, go in the opposite direction. Conclusions: The study has shown that the 3D techniques and technologies in combination with therapeutic laser systems could support not only a treatment plan, but they also directly influence the process of healing and reduce inflammation. The study was carried out under clinical project No. 00064203 (FN MOTOL).

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc22025362
003      
CZ-PrNML
005      
20221031100751.0
007      
ta
008      
221017s2022 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1089/photob.2022.0021 $2 doi
035    __
$a (PubMed)35788146
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Sediva, Eliska $u Department of Stomatology, 2nd Medical Faculty, Motol University Hospital, Charles University, Prague, Czech Republic
245    10
$a Photobiomodulation Therapy After Mesiodens Surgery: Evaluation of Immunological Markers and Three-Dimensional X-Ray Analysis-Placebo-Controlled Study / $c E. Sediva, T. Dostalova, P. Urbanova, H. Eliasova, S. Podzimek, E. Misova
520    9_
$a Objective: Photobiomodulation therapy (PBMT) applies therapeutic lasers or light-emitting diodes radiation to the surface of the body. From the medical point of view, PBMT systems have been employed for reducing pain, inflammation, and edema, promoting healing of wounds, deeper tissues and nerves, preventing tissue damage, etc. Background data: PBMT or biostimulation has a wide range of applications in maxillofacial surgery. It is known that the therapy effect using three-dimensional (3D) image was not really clear during the healing process. Materials and methods: The treatment group comprised 38 patients, 18 of them were treated with laser radiation (diode laser 808 nm) and 20 patients presented the control group. The surgery plan was monitored using cone beam computed tomography, in particular the number, shape, and size of mesiodens were registered. The effectivity of laser therapy was assessed based on immunological tests-secretory immunoglobulin A (sIgA) and lysozyme levels measured in nonstimulated saliva before and after treatment. Results: For sIgA (both in millimeters and milligrams per liter), the measurements displayed differences between pre- and postsurgery values, the postsurgery values being significantly lower than the presurgery values. In addition, interaction with the laser treatment plan was found, meaning that the laser treatment affected the sIgA levels. The decrease in sIgA levels in the control group was statistically significant. However, there was no significant change in sIgA levels in the laser group. The lysozyme trends appeared to be identical to the sIgA levels, that is, rising in the laser group and decreasing in the control group. The initial values for each group, however, go in the opposite direction. Conclusions: The study has shown that the 3D techniques and technologies in combination with therapeutic laser systems could support not only a treatment plan, but they also directly influence the process of healing and reduce inflammation. The study was carried out under clinical project No. 00064203 (FN MOTOL).
650    _2
$a biologické markery $7 D015415
650    _2
$a lidé $7 D006801
650    _2
$a imunoglobulin A sekreční $7 D007071
650    _2
$a zánět $7 D007249
650    _2
$a lasery polovodičové $7 D054023
650    12
$a laserová terapie s nízkou intenzitou světla $x metody $7 D028022
650    _2
$a muramidasa $7 D009113
650    _2
$a rentgenové záření $7 D014965
655    _2
$a klinické zkoušky kontrolované $7 D018848
655    _2
$a časopisecké články $7 D016428
700    1_
$a Dostalova, Tatjana $u Department of Stomatology, 2nd Medical Faculty, Motol University Hospital, Charles University, Prague, Czech Republic $1 https://orcid.org/0000000193213360
700    1_
$a Urbanova, Petra $u Department of Anthropology, Faculty of Science, Masaryk University, Brno, Czech Republic
700    1_
$a Eliasova, Hana $u Police of the Czech Republic, Institute of Criminalistics, Prague, Czech Republic
700    1_
$a Podzimek, Stepan $u Institute of Dental Medicine, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czech Republic
700    1_
$a Misova, Eva $u Institute of Dentistry and Oral Sciences, Palacky University, Olomouc, Czech Republic
773    0_
$w MED00208711 $t Photobiomodulation, photomedicine, and laser surgery $x 2578-5478 $g Roč. 40, č. 7 (2022), s. 472-479
856    41
$u https://pubmed.ncbi.nlm.nih.gov/35788146 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20221017 $b ABA008
991    __
$a 20221031100749 $b ABA008
999    __
$a ok $b bmc $g 1854866 $s 1176652
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2022 $b 40 $c 7 $d 472-479 $e 20220704 $i 2578-5478 $m Photobiomodulation, photomedicine, and laser surgery $n Photobiomodul Photomed Laser Surg $x MED00208711
LZP    __
$a Pubmed-20221017
Zpět

Najít záznam

Citační ukazatele

Možnosti archivace