-
Je něco špatně v tomto záznamu ?
Stereotactic Body Radiotherapy (SBRT) of Pancreatic Cancer-A Critical Review and Practical Consideration
P. Burkoň, J. Trna, M. Slávik, R. Němeček, T. Kazda, P. Pospíšil, M. Dastych, M. Eid, I. Novotný, T. Procházka, M. Vrzal
Status neindexováno Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, přehledy
NLK
Directory of Open Access Journals
od 2013
PubMed Central
od 2013
Europe PubMed Central
od 2013
ProQuest Central
od 2013-01-01
Open Access Digital Library
od 2013-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2013
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Pancreatic cancer is the third leading cause of cancer death in the developed world and is predicted to become the second by 2030. A cure may be achieved only with surgical resection of an early diagnosed disease. Surgery for more advanced disease is challenging and can be contraindicated for many reasons. Neoadjuvant therapy may improve the probability of achieving R0 resection. It consists of systemic treatment followed by radiation therapy applied concurrently or sequentially with cytostatics. A novel approach to irradiation, stereotactic body radiotherapy (SBRT), has the potential to improve treatment results. SBRT can deliver higher doses of radiation to the tumor in only a few treatment fractions. It has attracted significant interest for pancreatic cancer patients, as it is completed quickly, requires less time away from full-dose chemotherapy, and is well-tolerated than conventional radiotherapy. In this review, we aim to provide the reader with a basic overview of current evidence for SBRT indications in the treatment of pancreatic tumors. In the second part of the review, we focus on practical information with respect to SBRT treatment plan preparation the performance of such therapy. Finally, we discuss future directions related to the use of magnetic resonance linear accelerators.
Department of Gastroenterology University Hospital Brno Jihlavska 340 20 625 00 Brno Czech Republic
Faculty of Medicine Masaryk University Kamenice 753 5 625 00 Brno Czech Republic
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22031614
- 003
- CZ-PrNML
- 005
- 20230127131235.0
- 007
- ta
- 008
- 230119s2022 sz f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3390/biomedicines10102480 $2 doi
- 035 __
- $a (PubMed)36289742
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Burkoň, Petr $u Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 57 Brno, Czech Republic $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $1 https://orcid.org/0000000298639376
- 245 10
- $a Stereotactic Body Radiotherapy (SBRT) of Pancreatic Cancer-A Critical Review and Practical Consideration / $c P. Burkoň, J. Trna, M. Slávik, R. Němeček, T. Kazda, P. Pospíšil, M. Dastych, M. Eid, I. Novotný, T. Procházka, M. Vrzal
- 520 9_
- $a Pancreatic cancer is the third leading cause of cancer death in the developed world and is predicted to become the second by 2030. A cure may be achieved only with surgical resection of an early diagnosed disease. Surgery for more advanced disease is challenging and can be contraindicated for many reasons. Neoadjuvant therapy may improve the probability of achieving R0 resection. It consists of systemic treatment followed by radiation therapy applied concurrently or sequentially with cytostatics. A novel approach to irradiation, stereotactic body radiotherapy (SBRT), has the potential to improve treatment results. SBRT can deliver higher doses of radiation to the tumor in only a few treatment fractions. It has attracted significant interest for pancreatic cancer patients, as it is completed quickly, requires less time away from full-dose chemotherapy, and is well-tolerated than conventional radiotherapy. In this review, we aim to provide the reader with a basic overview of current evidence for SBRT indications in the treatment of pancreatic tumors. In the second part of the review, we focus on practical information with respect to SBRT treatment plan preparation the performance of such therapy. Finally, we discuss future directions related to the use of magnetic resonance linear accelerators.
- 590 __
- $a NEINDEXOVÁNO
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Trna, Jan $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $u Department of Gastroenterology and Digestive Endoscopy, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 53 Brno, Czech Republic $u Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 53 Brno, Czech Republic $1 https://orcid.org/0000000331389736
- 700 1_
- $a Slávik, Marek $u Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 57 Brno, Czech Republic $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $1 https://orcid.org/0000000285915941
- 700 1_
- $a Němeček, Radim $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $u Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 53 Brno, Czech Republic
- 700 1_
- $a Kazda, Tomáš $u Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 57 Brno, Czech Republic $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $1 https://orcid.org/0000000172888975
- 700 1_
- $a Pospíšil, Petr $u Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 57 Brno, Czech Republic $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic
- 700 1_
- $a Dastych, Milan $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $u Department of Gastroenterology, University Hospital Brno, Jihlavska 340/20, 625 00 Brno, Czech Republic
- 700 1_
- $a Eid, Michal $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic $u Department of Hematology, Oncology and Internal Medicine, University Hospital Brno, Jihlavska 340/20, 625 00 Brno, Czech Republic $1 https://orcid.org/0000000244335326
- 700 1_
- $a Novotný, Ivo $u Department of Gastroenterology and Digestive Endoscopy, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 53 Brno, Czech Republic
- 700 1_
- $a Procházka, Tomáš $u Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 57 Brno, Czech Republic $u Faculty of Medicine, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic
- 700 1_
- $a Vrzal, Miroslav $u Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Zluty Kopec 7, 656 57 Brno, Czech Republic
- 773 0_
- $w MED00205373 $t Biomedicines $x 2227-9059 $g Roč. 10, č. 10 (2022)
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36289742 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20230119 $b ABA008
- 991 __
- $a 20230127131227 $b ABA008
- 999 __
- $a ok $b bmc $g 1889572 $s 1182947
- BAS __
- $a 3
- BAS __
- $a PreBMC-PubMed-not-MEDLINE
- BMC __
- $a 2022 $b 10 $c 10 $e 20221004 $i 2227-9059 $m Biomedicines $n Biomedicines $x MED00205373
- LZP __
- $a Pubmed-20230119