• Je něco špatně v tomto záznamu ?

The Choroid after Half-Dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy

EE. Christou, A. Katsanos, I. Georgalas, V. Kozobolis, C. Kalogeropoulos, M. Stefaniotou

. 2022 ; 65 (3) : 89-98. [pub] 20230202

Jazyk angličtina Země Česko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc23000890

PURPOSE: To characterize choroidal structure and vasculature after half-dose verteporfin photodynamic therapy (hd-vPDT) in eyes with chronic central serous chorioretinopathy using Enhanced Depth Imaging Optical Coherence Tomography (EDI OCT) and Optical Coherence Tomography Angiography (OCT-A). METHODS: This prospective case-control study included 10 eyes. Choroid was examined before and at 1 month following hd-vPDT. We measured choroidal thickness (CT) at subfoveal area and at 750 μm nasal and temporal of fovea and thickness of Haller and choriocapillaris/Sattler layers. Whole (WA), luminal (LA) and interstitial area (IA) at EDI-OCT, and perfusion density at OCT-A were analyzed. The unaffected fellow eyes were used for comparisons. RESULTS: Mean CT at subfoveal area and at 750 μm nasal and temporal of fovea, values of Haller and choriocapillaris/Sattler layers and those of WA, LA and IA were reduced, while PD increased at 1 month after hd-vPDT (all p < 0.001). There was a significant (p < 0.05) negative correlation (ρ = -0.658) between PD and post-treatment logMARVA. None of analyzed parameters reached values of unaffected fellow eye. CONCLUSION: Following hd-vPDT, choroidal thickness with both luminal and interstitial components markedly decreased, while perfusion of choriocapillaris improved.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc23000890
003      
CZ-PrNML
005      
20230505093208.0
007      
ta
008      
230307s2022 xr da f 000 0|eng||
009      
AR
024    7_
$a 10.14712/18059694.2022.24 $2 doi
035    __
$a (PubMed)36735886
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Christou, Evita Evangelia $u Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
245    14
$a The Choroid after Half-Dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy / $c EE. Christou, A. Katsanos, I. Georgalas, V. Kozobolis, C. Kalogeropoulos, M. Stefaniotou
520    9_
$a PURPOSE: To characterize choroidal structure and vasculature after half-dose verteporfin photodynamic therapy (hd-vPDT) in eyes with chronic central serous chorioretinopathy using Enhanced Depth Imaging Optical Coherence Tomography (EDI OCT) and Optical Coherence Tomography Angiography (OCT-A). METHODS: This prospective case-control study included 10 eyes. Choroid was examined before and at 1 month following hd-vPDT. We measured choroidal thickness (CT) at subfoveal area and at 750 μm nasal and temporal of fovea and thickness of Haller and choriocapillaris/Sattler layers. Whole (WA), luminal (LA) and interstitial area (IA) at EDI-OCT, and perfusion density at OCT-A were analyzed. The unaffected fellow eyes were used for comparisons. RESULTS: Mean CT at subfoveal area and at 750 μm nasal and temporal of fovea, values of Haller and choriocapillaris/Sattler layers and those of WA, LA and IA were reduced, while PD increased at 1 month after hd-vPDT (all p < 0.001). There was a significant (p < 0.05) negative correlation (ρ = -0.658) between PD and post-treatment logMARVA. None of analyzed parameters reached values of unaffected fellow eye. CONCLUSION: Following hd-vPDT, choroidal thickness with both luminal and interstitial components markedly decreased, while perfusion of choriocapillaris improved.
650    _2
$a lidé $7 D006801
650    12
$a centrální serózní chorioretinopatie $x farmakoterapie $7 D056833
650    _2
$a fotosenzibilizující látky $x terapeutické užití $7 D017319
650    _2
$a studie případů a kontrol $7 D016022
650    _2
$a fluoresceinová angiografie $x metody $7 D005451
650    _2
$a zraková ostrost $7 D014792
650    12
$a fotochemoterapie $x metody $7 D010778
650    _2
$a verteporfin $x terapeutické užití $7 D000077362
650    _2
$a choroidea $x diagnostické zobrazování $x krevní zásobení $7 D002829
650    _2
$a optická koherentní tomografie $x metody $7 D041623
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a chronická nemoc $7 D002908
655    _2
$a časopisecké články $7 D016428
700    1_
$a Katsanos, Andreas $u Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
700    1_
$a Georgalas, Ilias $u First Department of Ophthalmology, General Hospital of Athens G. Gennimatas, Medical School, National and Kapodistrian University of Athens, Greece
700    1_
$a Kozobolis, Vassilios $u Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece
700    1_
$a Kalogeropoulos, Christos $u Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
700    1_
$a Stefaniotou, Maria $u Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
773    0_
$w MED00010947 $t Acta Medica (Hradec Kralove) $x 1805-9694 $g Roč. 65, č. 3 (2022), s. 89-98
856    41
$u https://pubmed.ncbi.nlm.nih.gov/36735886 $y Pubmed
910    __
$a ABA008 $b A 3077 $c 1072 $y p $z 0
990    __
$a 20230307 $b ABA008
991    __
$a 20230505093203 $b ABA008
999    __
$a ok $b bmc $g 1928834 $s 1187085
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2022 $b 65 $c 3 $d 89-98 $e 20230202 $i 1805-9694 $m Acta Medica $n Acta Med. (Hradec Král.) $x MED00010947
LZP    __
$b NLK198 $a Pubmed-20230307

Najít záznam

Citační ukazatele

Možnosti archivace