• Je něco špatně v tomto záznamu ?

Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies

E. Selinger, M. Neuenschwander, A. Koller, J. Gojda, T. Kühn, L. Schwingshackl, J. Barbaresko, S. Schlesinger

. 2023 ; 63 (29) : 9926-9936. [pub] 20220516

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24001307

To summarize and evaluate the evidence on the health impact of a vegan diet, we conducted an umbrella review of systematic reviews and meta-analyses. PubMed, Cochrane Library, Web of Science and Epistemonikos were searched up to September 2021. Meta-analyses were recalculated by using a random effects model. The certainty of evidence (CoE) was evaluated by the GRADE approach. For the general healthy population, a vegan diet was effective for reducing body weight [MD (95% CI): -2.52 kg (-3.06, -1.98), n = 8 RCTs; moderate CoE] and was associated with further health benefits (with low CoE), including a lower risk of cancer incidence [SRR (95% CI): 0.84 (0.75, 0.95), n = 2] and a trend for lower risk of all-cause mortality [SRR (95% CI): 0.87 (0.75, 1.01), n = 2], as well as lower ApoB levels [MD (95% CI): -0.19 μmol/L (-0.23, -0.15), n = 7 RCTs). The findings suggested adverse associations for a vegan diet with risk of fractures [SRR (95% CI): 1.46 (1.03, 2.07), n = 3; low CoE]. For persons with diabetes or at high CVD risk, a vegan diet reduced measures of adiposity, total cholesterol, LDL and improved glycemic control (CoE moderate to low). A vegan diet may have the potential for the prevention of cardiometabolic health, but it may also impair bone health. More well-conducted primary studies are warranted.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24001307
003      
CZ-PrNML
005      
20240213094533.0
007      
ta
008      
240109s2023 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1080/10408398.2022.2075311 $2 doi
035    __
$a (PubMed)37962057
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Selinger, Eliška $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $u Centre for Public Health Promotion, National Institute of Public Health, Prague, Czech Republic $u Department of Internal Medicine, Královské Vinohrady University Hospital, Prague, Czech Republic $1 https://orcid.org/0000000212298575
245    10
$a Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies / $c E. Selinger, M. Neuenschwander, A. Koller, J. Gojda, T. Kühn, L. Schwingshackl, J. Barbaresko, S. Schlesinger
520    9_
$a To summarize and evaluate the evidence on the health impact of a vegan diet, we conducted an umbrella review of systematic reviews and meta-analyses. PubMed, Cochrane Library, Web of Science and Epistemonikos were searched up to September 2021. Meta-analyses were recalculated by using a random effects model. The certainty of evidence (CoE) was evaluated by the GRADE approach. For the general healthy population, a vegan diet was effective for reducing body weight [MD (95% CI): -2.52 kg (-3.06, -1.98), n = 8 RCTs; moderate CoE] and was associated with further health benefits (with low CoE), including a lower risk of cancer incidence [SRR (95% CI): 0.84 (0.75, 0.95), n = 2] and a trend for lower risk of all-cause mortality [SRR (95% CI): 0.87 (0.75, 1.01), n = 2], as well as lower ApoB levels [MD (95% CI): -0.19 μmol/L (-0.23, -0.15), n = 7 RCTs). The findings suggested adverse associations for a vegan diet with risk of fractures [SRR (95% CI): 1.46 (1.03, 2.07), n = 3; low CoE]. For persons with diabetes or at high CVD risk, a vegan diet reduced measures of adiposity, total cholesterol, LDL and improved glycemic control (CoE moderate to low). A vegan diet may have the potential for the prevention of cardiometabolic health, but it may also impair bone health. More well-conducted primary studies are warranted.
650    _2
$a lidé $7 D006801
650    12
$a dieta veganská $7 D000067269
650    _2
$a systematický přehled jako téma $7 D000078202
650    _2
$a tělesná hmotnost $7 D001835
650    12
$a nádory $x prevence a kontrola $7 D009369
650    _2
$a hodnocení rizik $7 D018570
655    _2
$a časopisecké články $7 D016428
700    1_
$a Neuenschwander, Manuela $u Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany $u German Center for Diabetes Research (DZD), Partner, Düsseldorf, Germany $1 https://orcid.org/0000000157612225
700    1_
$a Koller, Alina $u Faculty of Medicine, University of Zurich, Zurich, Switzerland $u Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
700    1_
$a Gojda, Jan $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $u Department of Internal Medicine, Královské Vinohrady University Hospital, Prague, Czech Republic $1 https://orcid.org/0000000279955947
700    1_
$a Kühn, Tilman $u Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany $u Faculty of Medicine and University Hospital, Heidelberg Institute of Global Health (HIGH), Heidelberg, Germany $u Institute for Global Food Security (IGFS), Queen's University, Belfast, UK $1 https://orcid.org/000000017702317X
700    1_
$a Schwingshackl, Lukas $u Institute for Evidence in Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany $1 https://orcid.org/0000000334077594
700    1_
$a Barbaresko, Janett $u Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany $1 https://orcid.org/0000000308552769
700    1_
$a Schlesinger, Sabrina $u Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany $u German Center for Diabetes Research (DZD), Partner, Düsseldorf, Germany $1 https://orcid.org/0000000342440832
773    0_
$w MED00001241 $t Critical reviews in food science and nutriton $x 1549-7852 $g Roč. 63, č. 29 (2023), s. 9926-9936
856    41
$u https://pubmed.ncbi.nlm.nih.gov/37962057 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20240109 $b ABA008
991    __
$a 20240213094530 $b ABA008
999    __
$a ok $b bmc $g 2049750 $s 1211001
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2023 $b 63 $c 29 $d 9926-9936 $e 20220516 $i 1549-7852 $m Critical reviews in food science and nutriton $n Crit Rev Food Sci Nutr $x MED00001241
LZP    __
$a Pubmed-20240109

Najít záznam

Citační ukazatele

Možnosti archivace