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The relationship between atherosclerosis and dementia
J. Janoutová, O. Machaczka, M. Kovalová, A. Zatloukalová, P. Ambroz, V. Koutná, E. Mrázková, M. Bar, M. Roubec, P. Bártová, R. Novobilský, M. Sabela, P. Kušnierová, D. Stejskal, L. Faldynová, S. Walczysková, M. Vališ, L. Školoudík, P. Šolínová,...
Language English Country Czech Republic
Document type Journal Article
Digital library NLK
Source
NLK
Free Medical Journals
from 2004
ProQuest Central
from 2009-03-01 to 6 months ago
Medline Complete (EBSCOhost)
from 2006-03-01 to 6 months ago
Nursing & Allied Health Database (ProQuest)
from 2009-03-01 to 6 months ago
Health & Medicine (ProQuest)
from 2009-03-01 to 6 months ago
Public Health Database (ProQuest)
from 2009-03-01 to 6 months ago
ROAD: Directory of Open Access Scholarly Resources
from 1993
PubMed
38669152
DOI
10.21101/cejph.a7848
Knihovny.cz E-resources
- MeSH
- Atherosclerosis * epidemiology MeSH
- Dementia * epidemiology MeSH
- Middle Aged MeSH
- Humans MeSH
- Surveys and Questionnaires MeSH
- Risk Factors MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Case-Control Studies MeSH
- Life Style MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
OBJECTIVE: The main objective is to confirm a hypothesis that atherosclerosis, through various mechanisms, considerably influences cognitive impairment and significantly increases the risk for developing dementia. Complete sample should be 920 individuals. The present study aimed to analyse epidemiological data from a questionnaire survey. METHODS: The work was carried out in the form of an epidemiological case control study. Subjects are enrolled in the study based on results of the following examinations carried out in neurology departments and outpatient centres during the project NU20-09-00119 from 2020 to 2023. Respondents were divided into four research groups according to the results of clinical examination for the presence of atherosclerosis and dementia. The survey was mainly concerned with risk factors for both atherosclerosis and dementia. It contained questions on lifestyle factors, cardiovascular risk factors, leisure activities, and hobbies. RESULTS: Analysis of the as yet incomplete sample of 877 subjects has yielded the following selected results: on average, 16% of subjects without dementia had primary education while the proportion was 45.2% in the group with both dementia and atherosclerosis. Subjects with dementia did mainly physical work. Low physical activity was more frequently noted in dementia groups (Group 2 - 54.4% and Group 3 - 47.2%) than in subjects without dementia (Group 1 - 19.6% and Group 4 - 25.8%). Coronary heart disease was more frequently reported by dementia patients (33.95%) than those without dementia (16.05%). CONCLUSION: Cognitively impaired individuals, in particular those with vascular cognitive impairment, have poorer quality of life and shorter survival. Risk factors contributing to such impairment are similar to those for ischaemic or haemorrhagic stroke. It may be concluded that most of the analysed risk factors play a role in the development of both atherosclerosis and dementia.
Centre for Health Research Faculty of Medicine University of Ostrava Ostrava Czech Republic
Department of Laboratory Medicine University Hospital Ostrava Ostrava Czech Republic
Department of Neurology University Hospital Ostrava Ostrava Czech Republic
Faculty of Medicine in Hradec Kralove Charles University Hradec Kralove Czech Republic
Institute of Laboratory Medicine Faculty of Medicine University of Ostrava Ostrava Czech Republic
University Hospital Hradec Kralove Hradec Kralove Czech Republic
References provided by Crossref.org
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