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Ramsay Hunt syndrome in atopic dermatitis patient treated with dupilumab
J. Čelakovská, P. Boudková, V. Wertzova, L. Čáková
Language English Country Netherlands
Document type Case Reports, Journal Article, Letter
- MeSH
- Acyclovir therapeutic use MeSH
- Antiviral Agents therapeutic use adverse effects MeSH
- Dermatitis, Atopic * drug therapy MeSH
- Asthma drug therapy MeSH
- Herpes Zoster Oticus * drug therapy diagnosis MeSH
- Antibodies, Monoclonal, Humanized * therapeutic use adverse effects MeSH
- Middle Aged MeSH
- Humans MeSH
- Herpesvirus 3, Human MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Letter MeSH
- Case Reports MeSH
The Ramsay-Hunt syndrome results from reactivation of the varicella-zoster virus at the geniculate ganglion level. The syndrome is characterized by a combination of symptoms such as ipsilateral facial paralysis, otalgia, and vesicles near the ear and auditory canal. The gold standard in the treatment of Ramsay-Hunt syndrome remains the combination of antiviral therapy with corticosteroids and adequate analgesic therapy. We present a case of a 45-year-old patient with severe form of atopic dermatitis, who developed this syndrome during treatment with dupilumab. The risks and benefits of dupilumab treatment in this patient were considered. Because both bronchial asthma and atopic dermatitis worsened when dupilumab was discontinued, it was indicated to continue this therapy with low-dose of acyclovir.
References provided by Crossref.org
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- $a Čelakovská, Jarmila $u Department of Dermatology and Venereology, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové 50002, Czech Republic. Electronic address: jarmila.celakovska@seznam.cz
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- $a The Ramsay-Hunt syndrome results from reactivation of the varicella-zoster virus at the geniculate ganglion level. The syndrome is characterized by a combination of symptoms such as ipsilateral facial paralysis, otalgia, and vesicles near the ear and auditory canal. The gold standard in the treatment of Ramsay-Hunt syndrome remains the combination of antiviral therapy with corticosteroids and adequate analgesic therapy. We present a case of a 45-year-old patient with severe form of atopic dermatitis, who developed this syndrome during treatment with dupilumab. The risks and benefits of dupilumab treatment in this patient were considered. Because both bronchial asthma and atopic dermatitis worsened when dupilumab was discontinued, it was indicated to continue this therapy with low-dose of acyclovir.
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