• Something wrong with this record ?

Schwannian and Perineuriomatous Differentiation in a Series of Giant Congenital Melanocytic Nevi

I. Kletskaya, I. Belousova, O. Makarova, A. Narbutov, R. Oganesyan, M. Donati, J. Říčař, CM. Salgado, M. Reyes-Múgica, DV. Kazakov

. 2024 ; 46 (8) : 483-491. [pub] 20240606

Language English Country United States

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc24019551

Close relationship between melanocytes and neural cells is accepted to reflect their common derivation from the neural crest and tumors combining both elements. We present a series of 10 patients with giant congenital melanocytic nevi (CMN) in which a secondary proliferation (11 lesions) with schwannian and/or perineuriomatous differentiation developed in the course of the disease. The age of the patients (4 male and 6 female) at the time of surgery and histological assessment varied from 3 months to 57 years. Histopathologically, the following subgroups were delineated: (1) nodular/tumoriform "neurotization" in CMN, (2) diffuse neurofibroma-like proliferation within CMN, (3) plexiform neurofibroma-like proliferation within CMN, and (4) diffuse perineuriomatous (hybrid schwannomatous-perineuriomatous) differentiation in CMN. We review the pertinent literature, including the role of recently identified Schwann cell precursors which are believed to represent the nerve-associated state of neural crest-like cells that persists into later developmental stages.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24019551
003      
CZ-PrNML
005      
20241024110803.0
007      
ta
008      
241015s2024 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1097/DAD.0000000000002754 $2 doi
035    __
$a (PubMed)38842402
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Kletskaya, Irina $u Russian Children's Clinical Hospital of Pirogov's Russian National Research Medical University of the Ministry of Healthcare, Russian Federation, Moscow, Russia $u Dmitry Rogachev's National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia
245    10
$a Schwannian and Perineuriomatous Differentiation in a Series of Giant Congenital Melanocytic Nevi / $c I. Kletskaya, I. Belousova, O. Makarova, A. Narbutov, R. Oganesyan, M. Donati, J. Říčař, CM. Salgado, M. Reyes-Múgica, DV. Kazakov
520    9_
$a Close relationship between melanocytes and neural cells is accepted to reflect their common derivation from the neural crest and tumors combining both elements. We present a series of 10 patients with giant congenital melanocytic nevi (CMN) in which a secondary proliferation (11 lesions) with schwannian and/or perineuriomatous differentiation developed in the course of the disease. The age of the patients (4 male and 6 female) at the time of surgery and histological assessment varied from 3 months to 57 years. Histopathologically, the following subgroups were delineated: (1) nodular/tumoriform "neurotization" in CMN, (2) diffuse neurofibroma-like proliferation within CMN, (3) plexiform neurofibroma-like proliferation within CMN, and (4) diffuse perineuriomatous (hybrid schwannomatous-perineuriomatous) differentiation in CMN. We review the pertinent literature, including the role of recently identified Schwann cell precursors which are believed to represent the nerve-associated state of neural crest-like cells that persists into later developmental stages.
650    _2
$a lidé $7 D006801
650    12
$a pigmentový névus $x patologie $x vrozené $7 D009508
650    12
$a nádory kůže $x patologie $x vrozené $7 D012878
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a ženské pohlaví $7 D005260
650    12
$a buněčná diferenciace $7 D002454
650    _2
$a kojenec $7 D007223
650    12
$a Schwannovy buňky $x patologie $7 D012583
650    _2
$a dítě $7 D002648
650    _2
$a mladiství $7 D000293
650    _2
$a dospělí $7 D000328
650    _2
$a předškolní dítě $7 D002675
650    _2
$a lidé středního věku $7 D008875
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
700    1_
$a Belousova, Irena $u Department of Dermatology, Medical Military Academy, Saint Petersburg, Russia
700    1_
$a Makarova, Olga $u Russian Children's Clinical Hospital of Pirogov's Russian National Research Medical University of the Ministry of Healthcare, Russian Federation, Moscow, Russia
700    1_
$a Narbutov, Anton $u Russian Children's Clinical Hospital of Pirogov's Russian National Research Medical University of the Ministry of Healthcare, Russian Federation, Moscow, Russia
700    1_
$a Oganesyan, Raisa $u Dmitry Rogachev's National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia
700    1_
$a Donati, Michele $u Department of Pathology, University Hospital Campus Bio-Medico, Rome, Italy
700    1_
$a Říčař, Jan $u Department of Dermatology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
700    1_
$a Salgado, Claudia M $u Division of Pathology, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh; and
700    1_
$a Reyes-Múgica, Miguel $u Division of Pathology, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh; and
700    1_
$a Kazakov, Dmitry V $u IDP Institut für Dermatohistopathologie, Pathologie Institut Enge, Zürich, Switzerland
773    0_
$w MED00000240 $t The American Journal of dermatopathology $x 1533-0311 $g Roč. 46, č. 8 (2024), s. 483-491
856    41
$u https://pubmed.ncbi.nlm.nih.gov/38842402 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20241015 $b ABA008
991    __
$a 20241024110757 $b ABA008
999    __
$a ok $b bmc $g 2202026 $s 1231524
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 46 $c 8 $d 483-491 $e 20240606 $i 1533-0311 $m The American Journal of dermatopathology $n Am J Dermatopathol $x MED00000240
LZP    __
$a Pubmed-20241015

Find record

Citation metrics

Archiving options