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The ERA Registry Annual Report 2022: Epidemiology of Kidney Replacement Therapy in Europe, with a focus on sex comparisons

R. Boenink, M. Bonthuis, BA. Boerstra, ME. Astley, IR. Montez de Sousa, J. Helve, KS. Komissarov, J. Comas, D. Radunovic, L. Buchwinkler, K. Hommel, N. Gjorgjievski, AA. Galvão, N. Mitsides, MM. Vidas, AM. Dębska-Ślizień, C. Ambrus, MF....

. 2025 ; 18 (2) : sfae405. [pub] 20241212

Status not-indexed Language English Country England, Great Britain

Document type Journal Article, Review

The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with end-stage kidney disease (ESKD). This paper summarizes the ERA Registry Annual Report 2022, with a special focus on comparisons by sex. The supplement of this paper contains the complete ERA Registry Annual Report 2022. Data was collected from 53 national and regional KRT registries from 35 countries. Using this data, incidence, and prevalence of KRT, kidney transplantation rates, survival probabilities, and expected remaining lifetimes were calculated. In 2022, 530 million people of the European general population were covered by the ERA Registry. The incidence of KRT was 152 per million population (pmp). In incident patients, 54% were 65 years or older, 64% were male, and the most common primary renal disease (PRD) was diabetes mellitus (22%). At KRT initiation, 83% of patients received haemodialysis, 12% received peritoneal dialysis, and 5% underwent pre-emptive kidney transplantation. On 31 December 2022, the prevalence of KRT was 1074 pmp. In prevalent patients, 48% were 65 years or older, 62% were male, the most common PRD was of miscellaneous origin (18%), 56% of patients received haemodialysis, 5% received peritoneal dialysis, and 39% were living with a functioning graft. In 2022, the kidney transplantation rate was 40 pmp, with most kidneys coming from deceased donors (66%). For patients starting KRT between 2013 to 2017, 5-year survival probability was 52%. Compared with the general population, the expected remaining lifetime was 66% and 68% shorter for males and females, respectively, receiving dialysis, and 46% and 49% shorter for males and females, respectively, living with a functioning graft.

Abdominal Center Nephrology University of Helsinki and Helsinki University Hospital Helsinki Finland

Amsterdam Public Health Quality of Care and Ageing and Later Life Amsterdam The Netherlands

Amsterdam Public Health Quality of Care and Methodology Amsterdam The Netherlands

Austrian Dialysis and Transplantation Registry Department of Internal Medicine 4 Medical University Innsbruck Innsbruck Austria

B Braun Avitum Hungary Zrt Dialysis Center Budapest Budapest Hungary

Catalan Renal Registry Catalan Transplant Organization Health Department Generalitat of Catalonia Barcelona Spain

Clinic for Nephrology Clinical Center of Montenegro Podgorica Montenegro

Clinic of Nephrology Clinical Center of Serbia Belgrade Serbia

Clinical Nephrology Puerta de Hierro University Hospital Majadahonda Spain

Cyprus Renal Registry Health Monitoring Unit Ministry of Health Nicosia Cyprus

Department of Internal Diseases Riga Stradins University Riga Latvia

Department of Medicine 3rd Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady Prague Czechia

Department of Medicine Jönköping Regional Hospital Jönköping Sweden

Department of Nephrology and Hypertension IIS Fundacion Jimenez Diaz UAM Madrid Spain

Department of Nephrology Holbaek Hospital Holbaek Denmark

Department of Nephrology Pauls Stradins Clinical University Hospital Riga Latvia

Department of Transplantation Medicine Oslo University Hospital and Department of Pharmacy University of Oslo Oslo Norway

Division of Nephrology Internal Medicine Services Landspitali University Hospital Reykjavik Iceland

ERA Registry Amsterdam UMC location University of Amsterdam Department of Medical Informatics Meibergdreef 9 Amsterdam The Netherlands

Faculty of Medicine Autonoma University of Madrid Madrid Spain

Faculty of Medicine Ss Cyril and Methodius Skopje North Macedonia

Faculty of Medicine Tel Aviv University Tel Aviv Israel

Faculty of Medicine University of Belgrade Belgrade Serbia

Finnish Registry for Kidney Diseases Finnish Institute for Health and Welfare Helsinki Finland

Health Quality Assessment and Information System Service Dirección General de Programas Asistenciales Servicio Canario de la Salud Canary Islands Spain

Hospital Universitario de Navarra Pamplona Navarra Spain

Institute of Nephrology and Hypertension Sheba Medical Center Ramat Gan Israel

Institute of Nephrology Stadtspital Zürich Zürich Switzerland

Istanbul Üniversity Cerrahpasa Cerrahpasa Medical Faculty Istanbul Turkey

Lithuanian Nephrology Dialysis and Transplantation Association Lithuania

Medical University of Gdańsk Department of Nephrology Transplantology and Internal Diseases Gdańsk Poland

Murcia Renal Registry Department of Epidemiology Murcia Regional Health Council Murcia Spain

Nefrodata Dutch Renal Registry Utrecht the Netherlands

Nephrology Clinic University Clinical Centre of Kosovo Prishtina Kosovo

Nephrology Department Medical Academy Lithuanian University of Health Sciences Kaunas Lithuania

Nephrology department Nicosia General Hospital State Healthcare Services Organisation Nicosia Cyprus

Nephrology Department Valdecilla Hospital University of Cantabria IDIVAL Santander Spain

Portuguese Society of Nephrology Nephrology Service at the University Hospitals of Coimbra Coimbra Portugal

Registry of La Rioja Department Nephrology Hospital San Pedro Logroño La Rioja Spain

Registry of Renal Patients of the Valencian Community Dirección General de Salud Pública Valencia Spain

REIN registry Agence de la Biomédecine Saint Denis La Plaine Saint Denis France

RICORS2040 Madrid Spain

Scottish Renal Registry Public Health Scotland Glasgow UK

Slovak Medical University Faculty of Medicine Bratislava Slovakia

St Imre Teaching Hospital Div Nephrology Hypertension Budapest Hungary

State Institution Minsk Scientific and Practical Center for Surgery Transplantology and Hematology Minsk Belarus

Tartu University Faculty of Medicine Department of Internal Medicine Tartu Estonia

Tartu University Hospital Department of Internal Medicine Tartu Estonia

Transplant Autonomic Coordination Department Health Service of Castilla y León Castilla y León Spain

UK Renal Registry Bristol UK

University Clinic of Nephrology Skopje North Macedonia

University of Cyprus Shacolas Education Centre for Clinical Medicine Nicosia Cyprus

References provided by Crossref.org

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$a The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with end-stage kidney disease (ESKD). This paper summarizes the ERA Registry Annual Report 2022, with a special focus on comparisons by sex. The supplement of this paper contains the complete ERA Registry Annual Report 2022. Data was collected from 53 national and regional KRT registries from 35 countries. Using this data, incidence, and prevalence of KRT, kidney transplantation rates, survival probabilities, and expected remaining lifetimes were calculated. In 2022, 530 million people of the European general population were covered by the ERA Registry. The incidence of KRT was 152 per million population (pmp). In incident patients, 54% were 65 years or older, 64% were male, and the most common primary renal disease (PRD) was diabetes mellitus (22%). At KRT initiation, 83% of patients received haemodialysis, 12% received peritoneal dialysis, and 5% underwent pre-emptive kidney transplantation. On 31 December 2022, the prevalence of KRT was 1074 pmp. In prevalent patients, 48% were 65 years or older, 62% were male, the most common PRD was of miscellaneous origin (18%), 56% of patients received haemodialysis, 5% received peritoneal dialysis, and 39% were living with a functioning graft. In 2022, the kidney transplantation rate was 40 pmp, with most kidneys coming from deceased donors (66%). For patients starting KRT between 2013 to 2017, 5-year survival probability was 52%. Compared with the general population, the expected remaining lifetime was 66% and 68% shorter for males and females, respectively, receiving dialysis, and 46% and 49% shorter for males and females, respectively, living with a functioning graft.
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