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Proteomics-on-a-Chip - Microfluidics meets proteomics
H. Zhang, L. Zhao, J. Brodský, L. Migliaccio, I. Gablech, P. Neužil, M. You
Biosensors & bioelectronics.
2025 ;
273 (-) :
117122.
[pub] 20250109
Language English Country England, Great Britain
Document type Journal Article, Review
Persistent link
https://www.medvik.cz/link/bmc25009371
- MeSH
- Biosensing Techniques instrumentation methods MeSH
- Equipment Design MeSH
- Lab-On-A-Chip Devices * MeSH
- Humans MeSH
- Microfluidics methods MeSH
- Microfluidic Analytical Techniques instrumentation MeSH
- Proteins analysis isolation & purification MeSH
- Proteome analysis isolation & purification chemistry MeSH
- Proteomics * methods MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Proteomics provides an understanding of biological systems by enabling the detailed study of protein expression profiles, which is crucial for early disease diagnosis. Microfluidic-based proteomics enhances this field by integrating complex proteome analysis into compact and efficient systems. This review focuses on developing microfluidic chip structures for proteomics, covering on-chip sample pretreatment, protein extraction, purification, and identification in recent years. Furthermore, our work aims to inspire researchers to select proper methodologies in designing novel, efficient assays for proteomics applications by analyzing trends and innovations in this field.
Bioinspired Engineering and Biomechanics Center Xi'an Jiaotong University Xi'an 710049 PR China
TFX Group Xi'an Jiaotong University Institute of Life Health Xi'an 710049 PR China
References provided by Crossref.org
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