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Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK-air Study
B. Sousa-Pinto, EM. Costa, RJ. Vieira, L. Klimek, W. Czarlewski, O. Pfaar, A. Bedbrook, R. Amaral, L. Brussino, V. Kvedariene, DE. Larenas-Linnemann, T. Iinuma, N. Pham-Thi, FS. Regateiro, L. Taborda-Barata, MT. Ventura, IJ. Ansotegui, KC....
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články
PubMed
39956639
DOI
10.1111/cea.70004
Knihovny.cz E-zdroje
- MeSH
- adherence k farmakoterapii * MeSH
- antialergika terapeutické užití MeSH
- antihistaminika terapeutické užití MeSH
- dospělí MeSH
- flutikason terapeutické užití aplikace a dávkování MeSH
- ftalaziny terapeutické užití MeSH
- hormony kůry nadledvin terapeutické užití aplikace a dávkování MeSH
- lidé středního věku MeSH
- lidé MeSH
- průzkumy a dotazníky MeSH
- pyl imunologie MeSH
- roční období * MeSH
- sezónní alergická rýma * farmakoterapie epidemiologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Evropa MeSH
BACKGROUND: Adherence to rhinitis treatment has been insufficiently assessed. We aimed to use data from the MASK-air mHealth app to assess adherence to oral antihistamines (OAH), intra-nasal corticosteroids (INCS) or azelastine-fluticasone in patients with allergic rhinitis. METHODS: We included regular European MASK-air users with self-reported allergic rhinitis and reporting at least 1 day of OAH, INCS or azelastine-fluticasone. We assessed weeks during which patients answered the MASK-air questionnaire on all days. We restricted our analyses to data provided between January and June, to encompass the pollen seasons across the different assessed countries. We analysed symptoms using visual analogue scales (VASs) and the combined symptom-medication score (CSMS), performing stratified analyses by weekly adherence levels. Medication adherence was computed as the proportion of days in which patients reported rhinitis medication use. Sensitivity analyses were performed considering all weeks with at most 1 day of missing data and all months with at most 4 days of missing data. RESULTS: We assessed 8212 complete weeks (1361 users). Adherence (use of medication > 80% days) to specific drug classes ranged from 31.7% weeks for azelastine-fluticasone to 38.5% weeks for OAH. Similar adherence to rhinitis medication was found in users with or without self-reported asthma, except for INCS (better adherence in asthma patients). VAS and CSMS levels increased from no adherence to full adherence, except for INCS. A higher proportion of days with uncontrolled symptoms was observed in weeks with higher adherence. In full adherence weeks, 41.2% days reported rhinitis co-medication. The sensitivity analyses displayed similar results. CONCLUSIONS: A high adherence was found in patients reporting regular use of MASK-air. Different adherence patterns were found for INCS compared to OAH or azelastine-fluticasone that are likely to impact guidelines.
Agency of Health ASL Salerno Italy
Allergy and Clinical Immunology Unit Mauriziano Hospital Torino Italy
Allergy Center CUF Descobertas Hospital Lisbon Portugal
Allergy Department 2nd Pediatric Clinic University of Athens Athens Greece
Allergy Section Department of Internal Medicine Hospital Vall d'Hebron Barcelona Spain
Allergy Service Fundacion Jimenez Diaz Universidad Autonoma de Madrid CIBERES ISCIII Madrid Spain
ARADyAL Research Network Barcelona Spain
Asthma and Allergy Unit IRCCS Humanitas Research Hospital Rozzano Milan Italy
Center for Rhinology and Allergology Wiesbaden Germany
ClinCompetence Cologne GmbH Cologne Germany
Clinic of Asthma Allergy and Chronic Lung Diseases Vilnius Lithuania
Department of Allergology Medical University of Gdańsk Gdansk Poland
Department of Allergy and Immunology Hospital Quironsalud Bizkaia Bilbao Spain
Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy
Department of Immunoallergology Cova da Beira University Hospital Centre Covilhã Portugal
Department of Medical Sciences University of Torino Torino Italy
Department of Otolaryngology Head and Neck Surgery Eye and Ear University Hospital Beirut Lebanon
Department of Otolaryngology Head and Neck Surgery Universitätsmedizin Mainz Mainz Germany
Department of Otorhinolaryngology Amsterdam University Medical Centres AMC Amsterdam the Netherlands
Department of Otorhinolaryngology Chiba University Hospital Chiba Japan
Department of Otorhinolaryngology Head and Neck Surgery Dar Al Shifa Hospital Salmiya Kuwait
Department of Otorhinolaryngology Head and Neck Surgery Semmelweis University Budapest Hungary
Department of Pulmonary Diseases Celal Bayar University Faculty of Medicine Manisa Turkey
Department of Pulmonary Medicine CHU Liège Liège Belgium
Department of Respiratory Medicine and Tuberculosis University Hospital Brno Czech Republic
Department of Women's and Children's Health Paediatric Research Uppsala University Uppsala Sweden
Ecole Polytechnique de Palaiseau Palaiseau France
Faculty of Medicine University of Ljubljana Ljubljana Slovenia
Fundaçao ProAR Federal University of Bahia and GARD WHO Planning Group Salvador Bahia Brazil
GIGA I3 Research Group University of Liège Liège Belgium
Institute of Immunology Faculty of Medicine University of Coimbra Coimbra Portugal
Institute of Medical Statistics and Computational Biology University of Cologne Cologne Germany
Institute of Pulmonology and Tuberculosis Istanbul University Cerrahpaşa Istanbul Turkey
Institute of Sciences of Food Production National Research Council Bari Italy
KYomed INNOV Montpellier France
MASK Air SAS Montpellier France
Medical Consulting Czarlewski Levallois France
Medical Faculty ENT Department Eskisehir Osmangazi University Eskisehir Turkey
Postgraduate Program in Allergy and Clinical Immunology University of Naples Federico 2 Naples Italy
Respiralab Research Group Guayaquil Guayas Ecuador
Servicio de Alergia e Immunologia Clinica Santa Isabel Buenos Aires Argentina
Skin and Allergy Hospital Helsinki University Hospital and University of Helsinki Helsinki Finland
SOS Allergology and Clinical Immunology USL Toscana Centro Prato Italy
Universidad Espíritu Santo Samborondón Ecuador
Université Paris Cité Paris France
University Clinic of Respiratory and Allergic Diseases Golnik Slovenia
Citace poskytuje Crossref.org
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