Three-dimensional printing (3DP) has gained popularity among scientists and researchers in every field due to its potential to drastically reduce energy costs for the production of customized products by utilizing less energy-intensive machines as well as minimizing material waste. The 3D printing technology is an additive manufacturing approach that uses material layer-by-layer fabrication to produce the digitally specified 3D model. The use of 3D printing technology in the pharmaceutical sector has the potential to revolutionize research and development by providing a quick and easy means to manufacture personalized one-off batches, each with unique dosages, distinct substances, shapes, and sizes, as well as variable release rates. This overview addresses the concept of 3D printing, its evolution, and its operation, as well as the most popular types of 3D printing processes utilized in the health care industry. It also discusses the application of these cutting-edge technologies to the pharmaceutical industry, advancements in various medical fields and medical equipment, 3D bioprinting, the most recent initiatives to combat COVID-19, regulatory frameworks, and the major challenges that this technology currently faces. In addition, we attempt to provide some futuristic approaches to 3DP applications.

Biomedical Research Center University Hospital Hradec Kralove Sokolska 581 Hradec Kralove 50005 Czech Republic

Department of Biomedical Engineering and Measurement Faculty of Mechanical Engineering Technical University of Kosice Letna 1 9 Kosice Slovakia

Department of Chemistry Centre for Basic Sciences Pandit Ravishankar Shukla University Raipur 492010 Chhattisgarh India

Department of Chemistry Faculty of Science Center for Applied Technologies University of Hradec Kralove Rokitanskeho 62 Hradec Kralove Czech Republic

Department of Engineering Sciences Ramrao Adik Institute of Technology DY Patil University Nerul Navi Mumbai Maharashtra 400706 India

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